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NCT06974773 · ClinicalTrials.gov registry record · NA

Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

A NA study of Endometriosis, sponsored by Samphire Group.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT06974773 is a NA study of Endometriosis that is actively recruiting participants, run by Samphire Group. The registered enrollment target is 120 participants, below the 262-participant average among 48 other Endometriosis trials with a reported enrollment target (54% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06974773, a NA study of Endometriosis, is actively recruiting participants, sponsored by Samphire Group.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis. The study also aims to assess the safety and usability of the device when used at home over several months. The main questions it aims to answer are: 1. Does at-home transcranial direct current stimulation (tDCS) reduce daily pain intensity in women with endometriosis? 2. Does the device also improve mood and sleep quality? Researchers will compare two groups-one receiving active brain stimulation and one receiving a sham (placebo) stimulation-to see if the active device provides greater improvements in symptoms. Participants will: 1. Use the NettleEndo device at home for 20 minutes per session, five times per week for 12 weeks 2. Be randomly assigned to receive either real or sham stimulation through the device 3. Complete daily and weekly symptom ratings through a mobile app 4. Be followed for 90 days after completing the intervention to monitor longer-term effects All activities are completed remotely using a smartphone app. Participants can contact the study team with questions at any time. The study is double-blind, meaning neither participants nor the researchers assessing outcomes will know who received active or sham treatment until the end of the trial.

Conditions Studied

Endometriosis

Interventions

  • DEVICE NettleEndo
  • DEVICE Sham NettleEndo Device

Study Locations (1)

California

  • Alethios, Inc. - San Francisco

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-12-04
Est. Completion 2026-08-01
Phase NA

Sponsor

Samphire Group

2 total trials

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What the Registry Record Tells You About NCT06974773

The ClinicalTrials.gov registry entry for NCT06974773 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 262-participant average among 48 other Endometriosis trials with a reported enrollment target (54% lower). The listed sponsor is Samphire Group, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Endometriosis appearing as the primary indexed condition, and to 2 interventions - of which NettleEndo is the first listed.

NCT06974773 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06974773 about?

NCT06974773 is a clinical study titled "Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups". The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis. The study also aims to assess the safety and usability of the device when used at home over several months. The main...

What is the current status of trial NCT06974773?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-12-04. Estimated completion is 2026-08-01.

What conditions does trial NCT06974773 study?

This clinical trial studies the following conditions: Endometriosis.

What interventions are being tested in trial NCT06974773?

The interventions under investigation include: NettleEndo (DEVICE), Sham NettleEndo Device (DEVICE).

Who is sponsoring clinical trial NCT06974773?

This trial is sponsored by Samphire Group, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06974773 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.