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ClinicalTrials.gov 22 recruiting now early-phase tilt

Duchenne Muscular Dystrophy: early-phase trial registry

22 of 49 indexed Duchenne Muscular Dystrophy trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #281 of 28,707 conditions by registered trial count.

49 US clinical trials · 22 currently recruiting · #281 of 28,707 conditions by registered trial count

Duchenne Muscular Dystrophy: 49 US clinical trials tracked, 22 recruiting.

Duchenne Muscular Dystrophy is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 22 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most active sponsor is NS Pharma, running 4 of these trials.

Enrollment posture brief

Registry condition duchenne-muscular-dystrophy

OPEN 22 | RECR 45% | LATE 6 | EARLY 24 | RANK #281 | SPON 4

Nearest open-share peer: Psoriatic Arthritis (45% recruiting · 49 trials)

Endometriosis53.1%Diet, Healthy49%Duchenne Muscular Dystro (th…45%Chronic Disease36.7%Arthritis30.6%
Open-enrollment share among volume-matched conditions near Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy lists 22 open slots (45% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Duchenne Muscular Dystrophy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Duchenne Muscular Dystrophy is recruiting above its size-band peers.

    22 of 49 indexed trials (44.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Duchenne Muscular Dystrophy trials is spread across many organizations.

    NS Pharma accounts for 4 of 49 trials (8.2%). 33 distinct sponsors appear on at least one study for this condition label.

  3. Most Duchenne Muscular Dystrophy trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 49 trials that report a genuine target (sentinel values excluded). 35 of those (71.4%) plan for fewer than 100 participants.

  4. Duchenne Muscular Dystrophy splits between interventional and observational designs.

    32 interventional and 17 observational studies make up this index (65.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 19Phase 215Phase 34Phase 42

Open and recent trials

49 total, page 1 of 1

RECRUITING 10,000 participants

The Duchenne Registry

The Duchenne Registry

NCT02069756

RECRUITING 5,000 participants

CureDuchenne Link®: A Resource for Research

CureDuchenne

NCT04972604

RECRUITING 1,000 participants

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

xCures

NCT06539169

RECRUITING 550 participants

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

University of Florida

NCT01484678

RECRUITING 465 participants

Biomarker Development for Muscular Dystrophies

Massachusetts General Hospital

NCT05019625

RECRUITING 250 participants

Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

Catalyst Pharmaceuticals

NCT06564974

RECRUITING Phase 2 206 participants

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

Italfarma

NCT03373968

RECRUITING 200 participants

AFFINITY BEYOND: Anti-AAV8 Antibody Assessment Study of Males With DMD

REGENXBIO

NCT05683379

RECRUITING 100 participants

Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy

Massachusetts General Hospital

NCT05016908

RECRUITING 80 participants

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD

Vanderbilt University Medical Center

NCT06124196

RECRUITING Phase 2 65 participants

AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

REGENXBIO

NCT05693142

RECRUITING Phase 1 60 participants

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

Solid Biosciences

NCT06138639

RECRUITING Phase 2 51 participants

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Satellos Bioscience

NCT07287189

RECRUITING Phase 2 50 participants

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

Hoffmann-La Roche

NCT06450639

RECRUITING Phase 2 50 participants

Vasodilator and Exercise Study for DMD (VASO-REx)

University of Florida

NCT06290713

RECRUITING Phase 1 26 participants

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Wave Life Sciences

NCT04906460

RECRUITING Phase 4 26 participants

Once Weekly Infant Corticosteroid Trial for DMD

Anne M. Connolly

NCT05412394

RECRUITING Phase 1 20 participants

NS-050/NCNP-03 in Boys With DMD (Meteor50)

NS Pharma

NCT06053814

RECRUITING Phase 2 20 participants

NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

NS Pharma

NCT05996003

RECRUITING Phase 1 12 participants

A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

Insmed Gene Therapy

NCT06817382

RECRUITING 10 participants

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim

Vanderbilt University Medical Center

NCT06093100

RECRUITING Phase 1 8 participants

Trial of Cell Based Therapy for DMD

Masonic Cancer Center, University of Minnesota

NCT06692426

ACTIVE NOT RECRUITING 250 participants

Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD

Nationwide Children's Hospital

NCT02972580

ACTIVE NOT RECRUITING Phase 3 148 participants

A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)

Sarepta Therapeutics

NCT05881408

ACTIVE NOT RECRUITING Phase 3 114 participants

Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy

Pfizer

NCT04281485

ACTIVE NOT RECRUITING Phase 2 76 participants

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)

Edgewise Therapeutics

NCT05540860

ACTIVE NOT RECRUITING 75 participants

Pediatric Radio Frequency Coils Generic

Children's Hospital Medical Center, Cincinnati

NCT01633866

ACTIVE NOT RECRUITING Phase 2 43 participants

Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy

Edgewise Therapeutics

NCT06100887

ACTIVE NOT RECRUITING Phase 2 39 participants

Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping

Avidity Biosciences

NCT06244082

ACTIVE NOT RECRUITING Phase 2 25 participants

Tadalafil as Adjuvant Therapy for DMD

University of Florida

NCT05195775

ACTIVE NOT RECRUITING Phase 2 13 participants

Open-label Extension of the HOPE-2 Trial

Capricor

NCT04428476

ACTIVE NOT RECRUITING Phase 1 12 participants

Microdystrophin Gene Transfer Study in Adolescents and Children With DMD

Solid Biosciences

NCT03368742

ACTIVE NOT RECRUITING Phase 4 9 participants

Long-term Use of Viltolarsen in Boys With Duchenne Muscular Dystrophy in Clinical Practice (VILT-502)

NS Pharma

NCT04687020

COMPLETED 150 participants

Duchenne Muscular Dystrophy Video Assessment Registry

The Emmes Company

NCT05712447

COMPLETED Phase 3 126 participants

A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

Sarepta Therapeutics

NCT05096221

COMPLETED 73 participants

Electrical Impedance Myography and Ultrasound as Biomarkers of Duchenne Muscular Dystrophy

Boston Children's Hospital

NCT01491555

COMPLETED Phase 1 70 participants

Study of AOC 1044 in Healthy Adult Volunteers and Participants With Duchenne Muscular Dystrophy (DMD) Mutations Amenable to Exon 44 Skipping

Avidity Biosciences

NCT05670730

COMPLETED NA 53 participants

Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy

Nationwide Children's Hospital

NCT01645098

COMPLETED Phase 3 52 participants

Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy

Ohio State University

NCT02354352

COMPLETED 50 participants

This is a Study to Get More Information About Non Ambulatory Boys & Men With Duchenne Muscular Dystrophy

Washington University School of Medicine

NCT01098708

COMPLETED NA 42 participants

Eplerenone for Subclinical Cardiomyopathy in Duchenne Muscular Dystrophy

Subha Raman

NCT01521546

COMPLETED 39 participants

Wearable Technology to Assess Gait Function in SMA and DMD

Columbia University

NCT04193085

COMPLETED 31 participants

NSAA NON-Interventional Study Protocol

Red Nucleus Enterprise Solutions

NCT06054971

COMPLETED Phase 2 16 participants

Extension Study of NS-065/NCNP-01 in Boys With Duchenne Muscular Dystrophy (DMD)

NS Pharma

NCT03167255

COMPLETED Phase 2 14 participants

Study of Ataluren in ≥2 to <5 Year-Old Male Participants With Duchenne Muscular Dystrophy

PTC Therapeutics

NCT02819557

COMPLETED Phase 2 8 participants

Halt cardiomyOPathy progrEssion in Duchenne (HOPE-OLE)

Capricor

NCT06304064

COMPLETED Phase 2 6 participants

A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren

PTC Therapeutics

NCT03796637

COMPLETED Phase 1 4 participants

A Gene Transfer Therapy Study to Evaluate the Safety of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

Sarepta Therapeutics

NCT03375164

COMPLETED Phase 1 4 participants

Gentamicin Treatment of Muscular Dystrophy

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00005574

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 15
Phase 3 4
Phase 4 2

Top Sponsors

Named interventions

Most-linked intervention names on Duchenne Muscular Dystrophy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
delandistrogene moxeparvovec Genetic
3 trials
Ataluren Drug
2 trials
AOC 1044 Drug
2 trials
placebo Genetic
2 trials
Sevasemten Dose 3 Drug
2 trials
Sevasemten Dose 2 Drug
2 trials
Sevasemten Dose 1 Drug
2 trials

US sites by state

Facility locations filed on Duchenne Muscular Dystrophy trials. A trial with sites in several states counts in each.

California 24 trials
Ohio 22 trials
Florida 15 trials
Massachusetts 14 trials
Arkansas 13 trials
Texas 12 trials
Pennsylvania 12 trials
Illinois 12 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Duchenne Muscular Dystrophy page

49 registered trials, 22 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 22 Duchenne Muscular Dystrophy trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • NS Pharma sponsors the most Duchenne Muscular Dystrophy trials on record, review their full trial history before evaluating a specific study. See NS Pharma's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Duchenne Muscular Dystrophy condition card totals 49 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.