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Diabetes Mellitus, Type 2: full-pipeline trial registry
63 of 351 indexed Diabetes Mellitus, Type 2 trials are currently recruiting.
Corpus placement: #18 of 28,707 conditions by registered trial count.
351 US clinical trials · 63 currently recruiting · #18 of 28,707 conditions by registered trial count
Diabetes Mellitus, Type 2: 351 US clinical trials tracked, 63 recruiting.
Diabetes Mellitus, Type 2 is the subject of 351 registered US clinical trials on ClinicalTrials.gov, 63 of them currently open to new participants. 100 are in Phase 3-4 (later-stage) and 80 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 48 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus-type-2
OPEN 63 | RECR 18% | LATE 100 | EARLY 80 | RANK #18 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Acute Myelogenous Leukemia (18% recruiting · 39 trials)
Diabetes Mellitus, Type 2 lists 63 open slots (18% of 351 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus, Type 2 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetes Mellitus, Type 2 is recruiting below its size-band peers.
63 of 351 indexed trials (17.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetes Mellitus, Type 2 trials is spread across many organizations.
Novo Nordisk A/S accounts for 48 of 351 trials (13.7%). 143 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetes Mellitus, Type 2 enrolment sits around 150 participants.
Median target enrolment is 150 among the 349 trials that report a genuine target (sentinel values excluded). 142 of those (40.7%) plan for fewer than 100 participants.
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Diabetes Mellitus, Type 2 research is mostly interventional.
321 interventional and 30 observational studies make up this index (91.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
351 total, page 2 of 8
Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes
University of Washington
NCT05780905
Project Dulce for Arab Americans With Type 2 Diabetes
Scripps Whittier Diabetes Institute
NCT05580536
Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes
Pennington Biomedical Research Center
NCT05958368
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
San Diego State University
NCT05279729
Trial to Assess Continuous Glucose Monitoring in Asian Americans With Type 2 Diabetes
Joslin Diabetes Center
NCT05826678
Efficacy of Using Mobile Health Applications for Health
San Diego State University
NCT05589155
Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes
University of Pittsburgh
NCT07270016
Exercise and Time of Day in Type 2 Diabetes
Rutgers, The State University of New Jersey
NCT05108987
Improvement of Hyperglycemia/Diabetes in Patients to Improve Safety
Northwestern University
NCT06096311
OASIS: Peer Support for T2DM in Appalachia (Peer Coaches)
Brittany L Smalls
NCT06003634
Reversibility of Brain Glucose Transport in Type 2 Diabetes Mellitus (T2DM)
Yale University
NCT05776563
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
University of Nebraska
NCT06480786
Comparative Effectiveness of Empagliflozin in the US
Boehringer Ingelheim
NCT03363464
Signos DM2 Empowerment Study (SIGNOS-CGM-EMPOWER-201-2022)
Signos
NCT05874635
Weight Loss Clinical Decision Support
HealthPartners Institute
NCT05198765
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Novo Nordisk A/S
NCT03811561
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Eli Lilly and Company
NCT06260722
Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
Massachusetts General Hospital
NCT01762046
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Novo Nordisk A/S
NCT06534411
Kaiser Permanente Evaluating Nutritional Interventions in Food-Insecure High-Risk Adults Study
Kaiser Permanente
NCT06061861
A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight
Boehringer Ingelheim
NCT06066528
Integrating Abbott Point-of-Care Technologies and the Community Scientist Model to Support HbA1c Testing Per ADA
Sansum Diabetes Research Institute
NCT05000840
Empowering Veterans to Actively Communicate and Engage in Shared Decision Making in Medical Visits, A Randomized Controlled Trial
VA Office of Research and Development
NCT05169359
Biological Sample Repository for Gastrointestinal Disorders
Pichamol Jirapinyo, MD, MPH
NCT05874726
Addressing Basic Needs to Improve Diabetes Outcomes in Medicaid Beneficiaries
Washington University School of Medicine
NCT03940209
Decreasing Cardiovascular Risk for Patients With Diabetes
Michigan State University
NCT04874116
Glucose Monitoring Comparison in Primary Care
HealthPartners Institute
NCT05222815
Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology
Pennington Biomedical Research Center
NCT05523375
Using Early Time Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults With Type 2 Diabetes
University of Alabama at Birmingham
NCT04155619
Evaluating Telementoring for CHW-centered Diabetes Initiatives
The University of Texas Medical Branch, Galveston
NCT04835493
A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
University of California, Los Angeles
NCT04897945
Food Delivery, Remote Monitoring, and Coaching-Enhanced Education for Optimized Diabetes Management (FREEDOM)
University of Alabama at Birmingham
NCT05288452
Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes
VA Office of Research and Development
NCT03508934
A Family Dyad-focused Diabetes Self-Management Intervention for African American Adults
Ohio State University
NCT05905575
Food As MedicinE for Diabetes
University of North Carolina, Chapel Hill
NCT04828785
The Dietary Guidelines 3 Diet Patterns Study (DG3D): Phase 2
University of South Carolina
NCT05254496
The HIV, Adipose Tissue Immunology, and Metabolism Study
Vanderbilt University Medical Center
NCT04451980
Lowering Food Insecurity and Improving Diabetes With Financial Incentives
State University of New York at Buffalo
NCT05352022
A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy
Novo Nordisk A/S
NCT06797869
Diabetes Discharge Transitional CGM Study (DDT-CGM)
Intermountain Health Care
NCT04729985
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
University of Alabama at Birmingham
NCT04542148
Precision Diets for Diabetes Prevention
Stanford University
NCT03919877
Mastering Diabetes Study
Ohio University
NCT04454957
Surgical or Medical Treatment
Children's Hospital Medical Center, Cincinnati
NCT04128995
Electronic Diabetes Tune-Up Group (eDTU) for African Americans
Indiana University
NCT06321029
Study of Subcutaneously Administered ENT-03 for the Treatment of Obesity and Diabetes
Metabolics Pharma
NCT05925920
Michigan Men's Diabetes Project 2
University of Michigan
NCT05370781
Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans
University of Pittsburgh
NCT02710370
Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics
Washington University School of Medicine
NCT03348280
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 42 |
| Phase 2 | 38 |
| Phase 3 | 74 |
| Phase 4 | 26 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus, Type 2 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus, Type 2 trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus, Type 2 page
351 registered trials, 63 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 63 Diabetes Mellitus, Type 2 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Novo Nordisk A/S sponsors the most Diabetes Mellitus, Type 2 trials on record, review their full trial history before evaluating a specific study. See Novo Nordisk A/S's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus, Type 2 condition card totals 351 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.