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NCT07089784 · ClinicalTrials.gov registry record · Phase 1
Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)
A Phase 1 study of Diabetes Mellitus, Type 2, sponsored by Merck Sharp & Dohme.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 64
- Enrollment target
- 11
- Study locations
NCT07089784: Recruiting Phase 1 study of Diabetes Mellitus, Type 2, sponsored by Merck Sharp & Dohme.
NCT07089784 is a Phase 1 study of Diabetes Mellitus, Type 2 that is actively recruiting participants, run by Merck Sharp & Dohme. The registered enrollment target is 64 participants, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (99% lower). The trial reports 11 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07089784, a Phase 1 study of Diabetes Mellitus, Type 2, is actively recruiting participants, sponsored by Merck Sharp & Dohme.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 64 participants
- Enrollment target
- 11
- Study locations
Study Summary
The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensitivity C-reactive protein (hsCRP) in a person's blood.
Primary Outcome
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG MK-2828
Study Locations (11)
Florida
- Velocity Clinical Research, Hallandale Beach ( Site 0010) - Hallandale
- Jacksonville Center for Clinical Research ( Site 0002) - Jacksonville
- Advanced Pharma CR, LLC ( Site 0001) - Miami
- QPS Miami Research Associates ( Site 0005) - South Miami
California
- ProSciento Inc. ( Site 0004) - Chula Vista
- California Clinical Trials Medical Group managed by PAREXEL ( Site 0008) - Glendale
Missouri
- Alliance for Multispecialty Research, LLC ( Site 0013) - Kansas City
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0009) - Springfield
Kentucky
- AMR Lexington ( Site 0012) - Lexington
Tennessee
- AMR Clinical ( Site 0003) - Knoxville
Texas
- ICON Early Phase Services ( Site 0006) - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2025-09-22 |
| Est. Completion | 2026-06-29 |
| Phase | Phase 1 |
What NCT07089784 shows while recruiting
NCT07089784 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07089784 lists 11 locations in 6 states (Florida, California, Missouri).
Frequently Asked Questions
What is clinical trial NCT07089784 about?
NCT07089784 is a clinical study titled "Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)". The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensiti...
What is the current status of trial NCT07089784?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2025-09-22. Estimated completion is 2026-06-29.
What conditions does trial NCT07089784 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.
What interventions are being tested in trial NCT07089784?
The interventions under investigation include: Placebo (DRUG), MK-2828 (DRUG).
Who is sponsoring clinical trial NCT07089784?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07089784 being conducted?
This trial has 11 study locations across California, Florida, Kentucky, Missouri, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetes Mellitus, Type 2
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07089784's enrollment target sits among peer trials
64 236th of 348 higher than 113 of 348 other Diabetes Mellitus, Type 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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