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RECRUITING Phase 1

Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)

NCT07089784 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensitivity C-reactive protein (hsCRP) in a person's blood.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG MK-2828

Study Locations (11)

Florida

  • Velocity Clinical Research, Hallandale Beach ( Site 0010) — Hallandale
  • Jacksonville Center for Clinical Research ( Site 0002) — Jacksonville
  • Advanced Pharma CR, LLC ( Site 0001) — Miami
  • QPS Miami Research Associates ( Site 0005) — South Miami

California

  • ProSciento Inc. ( Site 0004) — Chula Vista
  • California Clinical Trials Medical Group managed by PAREXEL ( Site 0008) — Glendale

Missouri

  • Alliance for Multispecialty Research, LLC ( Site 0013) — Kansas City
  • Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0009) — Springfield

Kentucky

  • AMR Lexington ( Site 0012) — Lexington

Tennessee

  • AMR Clinical ( Site 0003) — Knoxville

Texas

  • ICON Early Phase Services ( Site 0006) — San Antonio

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2025-09-22
Est. Completion 2026-06-29
Phase Phase 1

Sponsor

Merck Sharp & Dohme

741 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07089784

The ClinicalTrials.gov registry entry for NCT07089784 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 64 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 741 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07089784 reports 11 study locations spanning 6 distinct geographic areas — top geographies include Florida, California, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07089784 about?

NCT07089784 is a clinical study titled "Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)". The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensiti...

What is the current status of trial NCT07089784?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 64 participants. The study started on 2025-09-22. Estimated completion is 2026-06-29.

What conditions does trial NCT07089784 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07089784?

The interventions under investigation include: Placebo (DRUG), MK-2828 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07089784?

This trial is sponsored by Merck Sharp & Dohme, which has 741 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07089784 being conducted?

This trial has 11 study locations across California, Florida, Kentucky, Missouri, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial