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Anxiety
Open-data reference.
367 US clinical trials · 148 currently recruiting
Active & Recent Trials
My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life
Northwestern University
NCT05369429
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
Duke University
NCT06595251
Evaluation of the PACE/PACENET BHL Clinical Program
University of Pennsylvania
NCT02463266
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
Massachusetts General Hospital
NCT06557005
REstoring Mental Health Through COmmUnity-based Psychological Services in New York City
George Washington University
NCT04913766
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
Duke University
NCT06596265
S.T.A.N.D. Alacrity Center Signature Project
University of California, Los Angeles
NCT05591937
RCT for Latina Mental Health Using Web-Based Apps
University of California, Los Angeles
NCT06874790
Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies
Jonsson Comprehensive Cancer Center
NCT07310004
External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy
Cefaly Technology
NCT06788977
Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings
Bradley Hospital
NCT06934525
Filipino Family Health Initiative 1.0
Kaiser Permanente
NCT06569303
The Nuestros Días ("Our Days") Study
University of Alabama at Birmingham
NCT06475534
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Duke University
NCT06538246
SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
Duke University
NCT06627764
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
Florida State University
NCT05748613
Cannabidiol and Older Adult Cannabis Users
University of Colorado, Boulder
NCT06290063
Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program
Penn State University
NCT05789446
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
Dana-Farber Cancer Institute
NCT06038318
Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
University of North Carolina, Chapel Hill
NCT06587230
P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety
Otsuka Pharmaceutical Development & Commercialization
NCT06973577
Change in Social Media Use and Well-being Among College Students Receiving a Two-week Exercise or Mindfulness Intervention
Johns Hopkins Bloomberg School of Public Health
NCT07097545
Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults
University of North Carolina, Chapel Hill
NCT06060860
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
VA Office of Research and Development
NCT06162741
Role of Parent Interpretation Bias in the Transmission of Anxiety to Children
Mclean Hospital
NCT05665491
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
Personalized Feedback Intervention for Latinx Drinkers With Anxiety
University of Houston
NCT05246202
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
VA Salt Lake City Health Care System
NCT06300255
M-O-M-S on the Bayou: Implementation of an Intervention for Mental Health in Pregnancy
Tulane University
NCT05838404
Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy
University of California, Los Angeles
NCT05908565
Digital Single Session Intervention for Youth Mental Health
Harvard University
NCT05449002
Animal Assisted Therapy in Pediatric Dentistry
University of North Carolina, Chapel Hill
NCT05464888
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Laureate Institute for Brain Research
NCT04426461
Testing FIRST in Youth Outpatient Psychotherapy
Harvard University
NCT04725721
Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women
University of California, Los Angeles
NCT06646692
Neonatal Neurodevelopmental Outcomes
Baylor College of Medicine
NCT07101757
Collaborative Care for Treatment of Depression and Anxiety
Kaiser Permanente
NCT06556589
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
University of Southern California
NCT04469790
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
M.D. Anderson Cancer Center
NCT05474846
Cannabis for Palliative Care in Cancer
University of Colorado, Boulder
NCT06266611
Brief Interventions for Coping with Distress
Teachers College, Columbia University
NCT05779761
Family Acceptance Project Online (Pilot RCT)
University of Michigan
NCT06839859
Adverse Adolescent Pathways to Substance Use
University of North Carolina, Chapel Hill
NCT06977178
Music Interventions During Wide-Awake Hand Surgery
University of Wisconsin, Madison
NCT05472909
Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department
Stony Brook University
NCT05540106
mHealth Mindfulness With Patients With Serious Illness and Their Caregivers
Rutgers, The State University of New Jersey
NCT05040711
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
Wake Forest University Health Sciences
NCT05625360
Novel Mental Health Therapies to Improve Military Readiness
David Moss
NCT05887713
The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program
Nova Southeastern University
NCT06652503
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Cedars-Sinai Medical Center
NCT05552053
Radiotherapy Patient Education With Virtual Reality
University of Miami
NCT06506435
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
Medical University of South Carolina
NCT07390786
RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty
University of Pittsburgh
NCT05658796
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders
Viome
NCT06502717
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Medical University of South Carolina
NCT07372586
Behavioral Exposure for Introceptive Tolerance RCT
Rutgers, The State University of New Jersey
NCT05398276
Test of Target Engagement of Ambiguity Aversion
Northwestern University
NCT06962527
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Baylor College of Medicine
NCT06537128
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
University of Cincinnati
NCT04623099
SilverCloud as a School-Based Intervention for Vulnerable Youth
NYU Langone Health
NCT06004414
Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life
Yale University
NCT05810259
Just-in-Time Training for Youth Mentors
University of Minnesota
NCT07129070
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
University of Michigan
NCT06563310
Developing Resilience and Anxiety Management Through the Arts
Case Western Reserve University
NCT07033052
Pramipexole to Enhance Social Connections
University of California, San Diego
NCT06269146
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
Portland State University
NCT06019377
Music Use in Parturients Admitted to Labor & Delivery
Tufts Medical Center
NCT06969105
Social Support and Reduced Fear Acquisition
University of California, Los Angeles
NCT04564976
Psilocybin-Assisted Therapy for Intergenerational Trauma
Rachel Yehuda
NCT06899165
Randomized Controlled Trial of a Behavioral Training App
New York University
NCT06447909
Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)
Northwestern University
NCT05942469
Social Support and Enhanced Fear Extinction
University of California, Los Angeles
NCT04565041
Pilot Study of Virtual Reality Therapy for Students With Anxiety
The University of Texas Health Science Center, Houston
NCT05319509
Amplification of Positivity for Alcohol Use
Laureate Institute for Brain Research
NCT06030154
Uncertainty and Firearms: Obtaining Secure Storage
Ohio State University
NCT05818696
Virtual Patient Groups for Sarcoidosis Associated Fatigue
The Cleveland Clinic
NCT07073963
Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons
University of Wisconsin, Madison
NCT06162624
Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population
Boston University Charles River Campus
NCT04895995
Mobile Mental Health Stigma Reduction Intervention Among Black Adults
Massachusetts General Hospital
NCT06316804
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
University of Oklahoma
NCT05934669
Expressive Writing on Minority Stressors Among Sexual Minority Veterans
VA Office of Research and Development
NCT05897021
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Georgia Institute of Technology
NCT03896529
Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest
Massachusetts General Hospital
NCT07143357
Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries
Boston Medical Center
NCT06812247
Stress Management Program
Stanford University
NCT06526585
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
University of Michigan
NCT06324383
Potential Benefits of Parent Child Interaction Therapy (PCIT)
University of Florida
NCT06827951
The Role of Virtual Reality During Regional Anesthesia
Cedars-Sinai Medical Center
NCT04163809
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
University of California, Los Angeles
NCT06073886
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
Reset Medical and Wellness Center
NCT07473505
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
University of Illinois at Chicago
NCT06261463
Sleep, Dreaming, and Virtual Reality for Mental Health
Northwestern University
NCT07408206
Music-Based Interventions, Aging, Alzheimer's Disease
University of Southern California
NCT06152211
Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures
Northwestern University
NCT05744336
Improving Minority Health Through Biofeedback and Stress Reduction
Amelia Saul, PhD, CTRS, BCB
NCT07172152
Effects of Virtual Reality Relaxation on the Anxiety Levels
Indiana University
NCT06804967
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)
University of Cincinnati
NCT04245436
Managing Anxiety in Pediatric Primary Care (MAPP)
UConn Health
NCT06104904
A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression
University of Florida
NCT07112001
Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities
Montclair State University
NCT06904508
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 13 |
| Phase 2 | 25 |
| Phase 3 | 6 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Trial Landscape
ClinicalTrials.gov lists 367 US studies indexed under Anxiety, and 148 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Anxiety shows 15 late-stage studies (Phase 3 and Phase 4 combined) alongside 38 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Anxiety is led by University of California, Los Angeles with 11 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety?
PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.