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ClinicalTrials.gov 7 recruiting now official registry

Acute Myelogenous Leukemia clinical trials

Every US clinical trial registered for Acute Myelogenous Leukemia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

39 US clinical trials · 7 currently recruiting

The research picture

Acute Myelogenous Leukemia has 39 registered US clinical trials, 7 of them open to new participants right now — about 18% of the total.

7
recruiting participants now
18%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
4
top sponsor: M.D. Anderson Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 1 266 participants

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

Beijing InnoCare Pharma Tech Co.

NCT06656494

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING Phase 2 36 participants

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Case Comprehensive Cancer Center

NCT06904482

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING 25 participants

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

Carevive Systems

NCT05974150

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING Phase 3 153 participants

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia

Actinium Pharmaceuticals

NCT02665065

ACTIVE NOT RECRUITING Phase 2 82 participants

DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission

Beth Israel Deaconess Medical Center

NCT03059485

ACTIVE NOT RECRUITING Phase 1 52 participants

Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia

Center for International Blood and Marrow Transplant Research

NCT03971799

ACTIVE NOT RECRUITING Phase 1 36 participants

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Bellicum Pharmaceuticals

NCT01744223

ACTIVE NOT RECRUITING Phase 1 28 participants

Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients

Beth Israel Deaconess Medical Center

NCT03679650

COMPLETED NA 506 participants

Selecting a Favorable KIR Donor in Unrelated HCT for AML

Masonic Cancer Center, University of Minnesota

NCT01288222

COMPLETED Phase 3 326 participants

A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)

Genzyme, a Sanofi Company

NCT00317642

COMPLETED Phase 2 202 participants

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00003838

COMPLETED Phase 2 153 participants

Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)

M.D. Anderson Cancer Center

NCT00414310

COMPLETED 119 participants

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

Notable Labs

NCT04014764

COMPLETED Phase 2 116 participants

A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II)

Genzyme, a Sanofi Company

NCT00373529

COMPLETED Phase 1 96 participants

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Bristol-Myers Squibb

NCT01120457

COMPLETED Phase 2 71 participants

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT00968071

COMPLETED Phase 1 66 participants

A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia

Mirati Therapeutics

NCT00324220

COMPLETED Phase 1 55 participants

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Washington University School of Medicine

NCT03755414

COMPLETED Phase 1 52 participants

ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies

AbbVie (prior sponsor, Abbott)

NCT01110473

COMPLETED Phase 1 47 participants

A Novel Sequential Treatment of Salvage and Reduced Intensity Conditioning (RIC) Chemotherapy for Allogeneic Stem-Cell Transplantation (SCT) for Primary Refractory and Relapsed Acute Myelogenous Leukemia (AML)

Weill Medical College of Cornell University

NCT00875693

COMPLETED Phase 1 37 participants

Epigenetic Reprogramming in Relapse/Refractory AML

Therapeutic Advances in Childhood Leukemia Consortium

NCT03263936

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francis

NCT00516152

COMPLETED Phase 1 36 participants

Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT00569010

COMPLETED Phase 1 36 participants

Lenalidomide Plus Chemotherapy for AML

Massachusetts General Hospital

NCT01681537

COMPLETED Phase 2 34 participants

Phase II 5-Azacytidine Plus VPA Plus ATRA

M.D. Anderson Cancer Center

NCT00326170

COMPLETED Phase 2 33 participants

Reduced Intensity Double Umbilical Cord Blood Transplantation

Massachusetts General Hospital

NCT01408563

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

COMPLETED Phase 1 30 participants

Dose Escalation, Safety and Pharmacokinetic Study of SAR103168 in Patients Refractory/ Relapsed Acute Leukemias or High-risk Myelodysplastic Syndromes

Sanofi

NCT00981240

COMPLETED Phase 1 30 participants

Study of Vaccination With Autologous Acute Myeloblastic Leukemia Cells in Patients With Advanced Myelodysplasia or Acute Myelogenous Leukemia

Dana-Farber Cancer Institute

NCT00136422

COMPLETED NA 26 participants

Low Dose Melphalan and Bortezomib for AML and High-Risk MDS

Dartmouth-Hitchcock Medical Center

NCT00789256

COMPLETED Phase 2 26 participants

SCT Plus Immune Therapy in Average Risk AML/MDS

New York Medical College

NCT02117297

COMPLETED Phase 2 25 participants

Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS

New York Medical College

NCT02221310

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 2 21 participants

A Study of Active Immunotherapy With GRNVAC1 in Patients With Acute Myelogenous Leukemia (AML)

Asterias Biotherapeutics

NCT00510133

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 17
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Myelogenous Leukemia Trial Landscape

ClinicalTrials.gov lists 39 US studies indexed under Acute Myelogenous Leukemia, and 7 of those are currently open to recruitment — roughly 18% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Acute Myelogenous Leukemia shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 31 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Acute Myelogenous Leukemia is led by M.D. Anderson Cancer Center with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 39 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Myelogenous Leukemia?

PlainTrial tracks 39 US clinical trials for Acute Myelogenous Leukemia, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Myelogenous Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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