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ClinicalTrials.gov 7 recruiting now early-phase tilt

Acute Myelogenous Leukemia: early-phase trial registry

7 of 39 indexed Acute Myelogenous Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #382 of 28,707 conditions by registered trial count.

39 US clinical trials · 7 currently recruiting · #382 of 28,707 conditions by registered trial count

Acute Myelogenous Leukemia: 39 US clinical trials tracked, 7 recruiting.

Acute Myelogenous Leukemia is the subject of 39 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 31 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

Enrollment posture brief

Registry condition acute-myelogenous-leukemia

OPEN 7 | RECR 18% | LATE 2 | EARLY 31 | RANK #382 | SPON 4

Nearest open-share peer: Diabetes Mellitus, Type 2 (18% recruiting · 351 trials)

Lung Carcinoma53.8%B-cell Lymphoma46.2%Binge-Eating Disorder43.6%Kidney Diseases38.5%Acute Myelogenous Leukem (th…18%
Open-enrollment share among volume-matched conditions near Acute Myelogenous Leukemia

Acute Myelogenous Leukemia lists 7 open slots (18% of 39 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Myelogenous Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Myelogenous Leukemia is recruiting below its size-band peers.

    7 of 39 indexed trials (17.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Acute Myelogenous Leukemia trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 4 of 39 trials (10.3%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Most Acute Myelogenous Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 37 among the 39 trials that report a genuine target (sentinel values excluded). 29 of those (74.4%) plan for fewer than 100 participants.

  4. Acute Myelogenous Leukemia research is mostly interventional.

    35 interventional and 4 observational studies make up this index (89.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 114Phase 217Phase 32

Open and recent trials

39 total, page 1 of 1

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 1 266 participants

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

Beijing InnoCare Pharma Tech Co.

NCT06656494

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING Phase 2 36 participants

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Case Comprehensive Cancer Center

NCT06904482

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING 25 participants

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

Carevive Systems

NCT05974150

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING Phase 3 153 participants

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia

Actinium Pharmaceuticals

NCT02665065

ACTIVE NOT RECRUITING Phase 2 82 participants

DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission

Beth Israel Deaconess Medical Center

NCT03059485

ACTIVE NOT RECRUITING Phase 1 52 participants

Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia

Center for International Blood and Marrow Transplant Research

NCT03971799

ACTIVE NOT RECRUITING Phase 1 36 participants

Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant

Bellicum Pharmaceuticals

NCT01744223

ACTIVE NOT RECRUITING Phase 1 28 participants

Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients

Beth Israel Deaconess Medical Center

NCT03679650

COMPLETED NA 506 participants

Selecting a Favorable KIR Donor in Unrelated HCT for AML

Masonic Cancer Center, University of Minnesota

NCT01288222

COMPLETED Phase 3 326 participants

A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)

Genzyme, a Sanofi Company

NCT00317642

COMPLETED Phase 2 202 participants

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00003838

COMPLETED Phase 2 153 participants

Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)

M.D. Anderson Cancer Center

NCT00414310

COMPLETED 119 participants

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

Notable Labs

NCT04014764

COMPLETED Phase 2 116 participants

A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II)

Genzyme, a Sanofi Company

NCT00373529

COMPLETED Phase 1 96 participants

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Bristol-Myers Squibb

NCT01120457

COMPLETED Phase 2 71 participants

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

M.D. Anderson Cancer Center

NCT00968071

COMPLETED Phase 1 66 participants

A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia

Mirati Therapeutics

NCT00324220

COMPLETED Phase 1 55 participants

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Washington University School of Medicine

NCT03755414

COMPLETED Phase 1 52 participants

ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies

AbbVie (prior sponsor, Abbott)

NCT01110473

COMPLETED Phase 1 47 participants

A Novel Sequential Treatment of Salvage and Reduced Intensity Conditioning (RIC) Chemotherapy for Allogeneic Stem-Cell Transplantation (SCT) for Primary Refractory and Relapsed Acute Myelogenous Leukemia (AML)

Weill Medical College of Cornell University

NCT00875693

COMPLETED Phase 1 37 participants

Epigenetic Reprogramming in Relapse/Refractory AML

Therapeutic Advances in Childhood Leukemia Consortium

NCT03263936

COMPLETED Phase 2 36 participants

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

University of California, San Francisco

NCT00516152

COMPLETED Phase 1 36 participants

Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

M.D. Anderson Cancer Center

NCT00569010

COMPLETED Phase 1 36 participants

Lenalidomide Plus Chemotherapy for AML

Massachusetts General Hospital

NCT01681537

COMPLETED Phase 2 34 participants

Phase II 5-Azacytidine Plus VPA Plus ATRA

M.D. Anderson Cancer Center

NCT00326170

COMPLETED Phase 2 33 participants

Reduced Intensity Double Umbilical Cord Blood Transplantation

Massachusetts General Hospital

NCT01408563

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

COMPLETED Phase 1 30 participants

Dose Escalation, Safety and Pharmacokinetic Study of SAR103168 in Patients Refractory/ Relapsed Acute Leukemias or High-risk Myelodysplastic Syndromes

Sanofi

NCT00981240

COMPLETED Phase 1 30 participants

Study of Vaccination With Autologous Acute Myeloblastic Leukemia Cells in Patients With Advanced Myelodysplasia or Acute Myelogenous Leukemia

Dana-Farber Cancer Institute

NCT00136422

COMPLETED NA 26 participants

Low Dose Melphalan and Bortezomib for AML and High-Risk MDS

Dartmouth-Hitchcock Medical Center

NCT00789256

COMPLETED Phase 2 26 participants

SCT Plus Immune Therapy in Average Risk AML/MDS

New York Medical College

NCT02117297

COMPLETED Phase 2 25 participants

Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS

New York Medical College

NCT02221310

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 2 21 participants

A Study of Active Immunotherapy With GRNVAC1 in Patients With Acute Myelogenous Leukemia (AML)

Asterias Biotherapeutics

NCT00510133

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 17
Phase 3 2

Named interventions

Most-linked intervention names on Acute Myelogenous Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
6 trials
Cyclophosphamide Drug
4 trials
Gemtuzumab Ozogamicin Drug
3 trials
Decitabine Drug
3 trials
Melphalan Drug
3 trials
Valproic Acid Drug
2 trials
Cytarabine Drug
2 trials
Azacitidine Drug
2 trials

US sites by state

Facility locations filed on Acute Myelogenous Leukemia trials. A trial with sites in several states counts in each.

Texas 14 trials
New York 13 trials
Massachusetts 12 trials
Ohio 10 trials
Illinois 9 trials
Georgia 9 trials
California 9 trials
Colorado 8 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Myelogenous Leukemia page

39 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Myelogenous Leukemia condition card totals 39 registered trials; most-linked intervention Fludarabine; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.