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NCT02969798 · ClinicalTrials.gov registry record · NA

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

A NA study of Diabetes Mellitus, Type 2 and Impaired Glucose Tolerance (IGT), sponsored by The University of Texas Health Science Center at San Antonio.

Recruiting
Registry status
NA
Development phase
700
Enrollment target
1
Study location

NCT02969798: Recruiting NA study of Diabetes Mellitus, Type 2 and Impaired Glucose Tolerance (IGT), sponsored by The University of Texas Health Science Center at San Antonio.

NCT02969798 is a NA study of Diabetes Mellitus, Type 2 and Impaired Glucose Tolerance (IGT) that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 700 participants, below the 4,483-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02969798, a NA study of Diabetes Mellitus, Type 2 and Impaired Glucose Tolerance (IGT), is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.

RECRUITING
Registry status
NA
Development phase
700 participants
Enrollment target
1
Study location

Study Summary

HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities in IGT and IFG will be required to optimally prevent the progressive beta cell failure and development of overt type 2 diabetes.

Primary Outcome

Beta cell function will be measured as insulin secretion during the hyperglycemic clamp (mean plasma insulin concentration in uU/ml) multiplied by insulin sensitivity measured with the euglycemic insulin clamp (mg/kg.min).

Interventions

  • DRUG Metformin
  • DRUG Pioglitazone
  • DRUG Dapagliflozin
  • DRUG Saxagliptin

Study Locations (1)

Texas

  • The University of Texas Health Science Center at San Antonio - San Antonio

Trial Details

FieldValue
Enrollment Target 700 participants
Start Date 2014-01-01
Est. Completion 2027-07
Phase NA

What NCT02969798 shows while recruiting

NCT02969798 is an interventional study that assigns participants to a tested intervention. The registered 700 participants enrollment target is mid-sized for trials with a published cap, below the 4,483-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (84% lower).

The record links to 3 conditions, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 4 interventions - of which Metformin is the first listed.

NCT02969798 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT02969798 about?

NCT02969798 is a clinical study titled "Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)". HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities in IGT and IFG will be required to optimally prevent the progressive be...

What is the current status of trial NCT02969798?

This trial is currently recruiting. It is a NA study. The enrollment target is 700 participants. The study started on 2014-01-01. Estimated completion is 2027-07.

What conditions does trial NCT02969798 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2, Impaired Glucose Tolerance (IGT), Impaired Fasting Glucose (IFG).

What interventions are being tested in trial NCT02969798?

The interventions under investigation include: Metformin (DRUG), Pioglitazone (DRUG), Dapagliflozin (DRUG), Saxagliptin (DRUG).

Who is sponsoring clinical trial NCT02969798?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02969798 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus, Type 2

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02969798's enrollment target sits among peer trials

700 55th of 348 higher than 294 of 348 other Diabetes Mellitus, Type 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02969798, the US trial registry maintained by the National Library of Medicine. NCT02969798 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.