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NCT06936670 · ClinicalTrials.gov registry record · NA

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

A NA study of Diabetes Mellitus, Type 2, sponsored by Seattle Children's Hospital.

Recruiting
Registry status
NA
Development phase
90
Enrollment target
2
Study locations

NCT06936670 is a NA study of Diabetes Mellitus, Type 2 that is actively recruiting participants, run by Seattle Children's Hospital. The registered enrollment target is 90 participants, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT06936670, a NA study of Diabetes Mellitus, Type 2, is actively recruiting participants, sponsored by Seattle Children's Hospital.

RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target
2
Study locations

Study Summary

High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only \~5 min/day and is thus ideal for youth with T2D (Y-T2D). Investigators seek to 1: assess changes in casual and 24-hr SBP, endothelial function, and arterial stiffness after 3 months of IMST vs. sham training in Y-T2D, 2: Define changes in eGFR andalbuminuria after 3 months of IMST vs. sham in Y-T2D, 3: Interrogate mechanisms of IMST by translational assessments of NO bioavailability, endothelial NO synthase (eNOS) activation, and ROS/oxidative stress, and determine the role of circulating factors.

Conditions Studied

Interventions

  • DEVICE Sham Training
  • DEVICE Inspiratory Muscle Strength Training (IMST)

Study Locations (2)

Washington

  • Seattle Children's Hospital - Seattle
  • University of Washington Medicine Diabetes Institute - Seattle

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2025-04-30
Est. Completion 2026-02-28
Phase NA

Sponsor

Seattle Children's Hospital

168 total trials

What the Registry Record Tells You About NCT06936670

The ClinicalTrials.gov registry entry for NCT06936670 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (98% lower). The listed sponsor is Seattle Children's Hospital, which has 168 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which Sham Training is the first listed.

NCT06936670 reports 2 study locations spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT06936670 about?

NCT06936670 is a clinical study titled "Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes". High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only \~5 min/day and is thus ideal for youth with T2D (Y-T2D). Investigators seek to 1: assess changes in casual and 24-hr SB...

What is the current status of trial NCT06936670?

This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2025-04-30. Estimated completion is 2026-02-28.

What conditions does trial NCT06936670 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT06936670?

The interventions under investigation include: Sham Training (DEVICE), Inspiratory Muscle Strength Training (IMST) (DEVICE).

Who is sponsoring clinical trial NCT06936670?

This trial is sponsored by Seattle Children's Hospital, which has 168 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06936670 being conducted?

This trial has 2 study locations across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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