Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06936670 · ClinicalTrials.gov registry record · NA

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

A NA study of Diabetes Mellitus, Type 2, sponsored by Seattle Children's Hospital.

Recruiting
Registry status
NA
Development phase
90
Enrollment target
2
Study locations

NCT06936670: Recruiting NA study of Diabetes Mellitus, Type 2, sponsored by Seattle Children's Hospital.

NCT06936670 is a NA study of Diabetes Mellitus, Type 2 that is actively recruiting participants, run by Seattle Children's Hospital. The registered enrollment target is 90 participants, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06936670, a NA study of Diabetes Mellitus, Type 2, is actively recruiting participants, sponsored by Seattle Children's Hospital.

RECRUITING
Registry status
NA
Development phase
90 participants
Enrollment target
2
Study locations

Study Summary

High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only \~5 min/day and is thus ideal for youth with T2D (Y-T2D). Investigators seek to 1: assess changes in casual and 24-hr SBP, endothelial function, and arterial stiffness after 3 months of IMST vs. sham training in Y-T2D, 2: Define changes in eGFR andalbuminuria after 3 months of IMST vs. sham in Y-T2D, 3: Interrogate mechanisms of IMST by translational assessments of NO bioavailability, endothelial NO synthase (eNOS) activation, and ROS/oxidative stress, and determine the role of circulating factors.

Primary Outcome

Measures of casual clinic and 24-hour ambulatory blood pressure monitoring

Conditions Studied

Interventions

  • DEVICE Sham Training
  • DEVICE Inspiratory Muscle Strength Training (IMST)

Study Locations (2)

Washington

  • Seattle Children's Hospital - Seattle
  • University of Washington Medicine Diabetes Institute - Seattle

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2025-04-30
Est. Completion 2026-02-28
Phase NA
Seattle Children's Hospital

168 total trials

What NCT06936670 shows while recruiting

NCT06936670 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which Sham Training is the first listed.

NCT06936670 reports a single indexed study location in Washington.

Frequently Asked Questions

What is clinical trial NCT06936670 about?

NCT06936670 is a clinical study titled "Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes". High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only \~5 min/day and is thus ideal for youth with T2D (Y-T2D). Investigators seek to 1: assess changes in casual and 24-hr SB...

What is the current status of trial NCT06936670?

This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2025-04-30. Estimated completion is 2026-02-28.

What conditions does trial NCT06936670 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT06936670?

The interventions under investigation include: Sham Training (DEVICE), Inspiratory Muscle Strength Training (IMST) (DEVICE).

Who is sponsoring clinical trial NCT06936670?

This trial is sponsored by Seattle Children's Hospital, which has 168 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06936670 being conducted?

This trial has 2 study locations across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes Mellitus, Type 2

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06936670's enrollment target sits among peer trials

90 212th of 348 higher than 137 of 348 other Diabetes Mellitus, Type 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus, Type 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02521311 · 90 participants · Phase 2

    Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

  • NCT02939573 · 90 participants · Phase 2

    A Randomized Multicenter Study for Isolated Skin Vasculitis

  • NCT03128879 · 90 participants · Phase 2

    Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL

  • NCT03184038 · 90 participants · NA

    Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06936670, the US trial registry maintained by the National Library of Medicine. NCT06936670 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.