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Coronary Artery Disease: later-stage trial registry
57 of 220 indexed Coronary Artery Disease trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #42 of 28,707 conditions by registered trial count.
220 US clinical trials · 57 currently recruiting · #42 of 28,707 conditions by registered trial count
Coronary Artery Disease: 220 US clinical trials tracked, 57 recruiting.
Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.
Enrollment posture brief
Registry condition coronary-artery-disease
OPEN 57 | RECR 26% | LATE 42 | EARLY 15 | RANK #42 | SPON 17
Volume-matched condition peers
Nearest open-share peer: Adenocarcinoma (26% recruiting · 27 trials)
Coronary Artery Disease lists 57 open slots (26% of 220 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Coronary Artery Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Coronary Artery Disease is recruiting below its size-band peers.
57 of 220 indexed trials (25.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Coronary Artery Disease trials is spread across many organizations.
University of Florida accounts for 17 of 220 trials (7.7%). 134 distinct sponsors appear on at least one study for this condition label.
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Typical Coronary Artery Disease enrolment sits around 266 participants.
Median target enrolment is 266 among the 220 trials that report a genuine target (sentinel values excluded). 70 of those (31.8%) plan for fewer than 100 participants.
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Coronary Artery Disease splits between interventional and observational designs.
153 interventional and 67 observational studies make up this index (69.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
220 total, page 1 of 5
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
Population Health Research Institute
NCT05701358
Factors Affect Outcomes in Cardiovascular Surgery
University of California, Davis
NCT01932411
Progress Bifurcation Global Registry
Minneapolis Heart Institute Foundation
NCT05100992
Progress Complication
Minneapolis Heart Institute Foundation
NCT05100940
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
University of British Columbia
NCT04634240
Assessment of Patients With suspeCted Coronary Artery Disease by Coronary calciUm fiRst strATegy vErsus Usual Care Approach.
Intermountain Health Care
NCT03972774
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
Weill Medical College of Cornell University
NCT04124120
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
Concept Medical
NCT06271590
AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention
Brigham and Women's Hospital
NCT06235112
Prevail Global Study
Medtronic Vascular
NCT06535854
Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
Cardiovascular Innovation and Research Institute
NCT03428048
Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
Semmelweis University
NCT07016477
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD
Cleerly
NCT06713239
SELUTION 4 De Novo Small Vessel IDE Trial
M.A. Med Alliance S.A.
NCT05946629
CTSN Embolic Protection Trial
Icahn School of Medicine at Mount Sinai
NCT06027788
RADIQAL Study (Radiation Dose and Image Quality Trial)
Philips Clinical & Medical Affairs Global
NCT06944509
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Sunnybrook Health Sciences Centre
NCT05427370
Virtue® SAB in the Treatment of Coronary ISR Trial
Orchestra BioMed
NCT07045194
The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial
VA Office of Research and Development
NCT05618353
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
Fundación EPIC
NCT07286578
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
Weill Medical College of Cornell University
NCT06399692
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities
Weill Medical College of Cornell University
NCT06399705
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
University of California, San Francisco
NCT05933083
Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health
Massachusetts General Hospital
NCT07087431
A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction
University of Florida
NCT05332262
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Concept Medical
NCT05908331
Clinical Impact of Cardiac Photon Counting CT
Mayo Clinic
NCT05240807
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
TECTONIC CAD IVL IDE Study
Abbott Medical Devices
NCT06885177
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
Kardion
NCT06445608
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
NewAmsterdam Pharma
NCT06305559
South Asians and Coronary Plaque Registry
University of Texas Southwestern Medical Center
NCT05367297
Etomidate Versus Propofol in CABG Surgery
Hartford Hospital
NCT06068764
Prevent Cardiac Surgery Associated AKI Trial
George Washington University
NCT06620523
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
MedTrace Pharma A/S
NCT05134012
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Change in Cardiovascular Health
Massachusetts General Hospital
NCT05819814
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine
Massachusetts General Hospital
NCT05850091
Digital Monitoring for Patients Post Coronary Interventions to Reduce Risk for Recurrent Adverse Cardiovascular Events
University of California, Davis
NCT06114615
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Aventusoft
NCT06567795
The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial
Ottawa Heart Institute Research Corporation
NCT03447938
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
NCT06779630
Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment
Annapoorna Kini
NCT07000045
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
Mayo Clinic
NCT05111288
Physiological Assessment of Severe Coronary Stenosis for Informing Planned PCI
Beth Israel Deaconess Medical Center
NCT05491668
Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.
XyloCor Therapeutics
NCT07048808
Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI
University of Florida
NCT05681702
Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study
University of Florida
NCT06821191
Study of Hepatitis Eradication Receiving Protease Inhibitor Administration
Sentara Norfolk General Hospital
NCT03886077
Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention
University of Florida
NCT06228456
Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors
University of Florida
NCT06691191
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 17 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Coronary Artery Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Coronary Artery Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Coronary Artery Disease page
220 registered trials, 57 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 57 Coronary Artery Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Coronary Artery Disease trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Coronary Artery Disease condition card totals 220 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.