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NCT06068764 · ClinicalTrials.gov registry record · Phase 4

Etomidate Versus Propofol in CABG Surgery

A Phase 4 study of Coronary Artery Disease, sponsored by Hartford Hospital.

Recruiting
Registry status
Phase 4
Development phase
300
Enrollment target
1
Study location

NCT06068764: Recruiting Phase 4 study of Coronary Artery Disease, sponsored by Hartford Hospital.

NCT06068764 is a Phase 4 study of Coronary Artery Disease that is actively recruiting participants, run by Hartford Hospital. The registered enrollment target is 300 participants, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06068764, a Phase 4 study of Coronary Artery Disease, is actively recruiting participants, sponsored by Hartford Hospital.

RECRUITING
Registry status
Phase 4
Development phase
300 participants
Enrollment target
1
Study location

Study Summary

The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods. To achieve this goal, participants who are scheduled for CABG surgery will be randomly assigned to receive either etomidate or propofol as the principal hypnotic agent. The researchers will then compare the effects of these two anesthesia induction agents on various factors, including the need for hemodynamic support, hemodynamic stability, duration of mechanical ventilation, length of stay in the intensive care unit (ICU), and overall hospital length of stay. Additionally, they will assess whether there are disparities in mortality rates and readmission rates within a 6-month timeframe after the surgery. By comparing the outcomes between the two groups, the study aims to provide valuable insights into the potential differences in vasopressor or ionotropic agent requirements between etomidate and propofol. This information can help inform clinical decision-making and potentially optimize anesthesia management strategies for patients undergoing CABG surgery.

Conditions Studied

Interventions

  • DRUG Propofol
  • DRUG Etomidate

Study Locations (1)

Connecticut

  • Hartford Hospital - Hartford

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-12-05
Est. Completion 2026-08
Phase Phase 4
Hartford Hospital

75 total trials

What NCT06068764 shows while recruiting

NCT06068764 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (77% lower).

The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which Propofol is the first listed.

NCT06068764 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT06068764 about?

NCT06068764 is a clinical study titled "Etomidate Versus Propofol in CABG Surgery". The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this ...

What is the current status of trial NCT06068764?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 300 participants. The study started on 2023-12-05. Estimated completion is 2026-08.

What conditions does trial NCT06068764 study?

This clinical trial studies the following conditions: Coronary Artery Disease.

What interventions are being tested in trial NCT06068764?

The interventions under investigation include: Propofol (DRUG), Etomidate (DRUG).

Who is sponsoring clinical trial NCT06068764?

This trial is sponsored by Hartford Hospital, which has 75 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06068764 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Artery Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06068764's enrollment target sits among peer trials

300 102nd of 219 higher than 116 of 219 other Coronary Artery Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06068764, the US trial registry maintained by the National Library of Medicine. NCT06068764 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.