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NCT07087431 · ClinicalTrials.gov registry record · NA

Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

A NA study of Coronary Artery Disease, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
500
Enrollment target
1
Study location

NCT07087431 is a NA study of Coronary Artery Disease that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 500 participants, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07087431, a NA study of Coronary Artery Disease, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
500 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not currently taking LDL cholesterol-lowering medications.

Conditions Studied

Interventions

  • BEHAVIORAL Immediate disclosure of CAD PRS results
  • BEHAVIORAL Deferred Disclosure of CAD PRS results

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2025-10-15
Est. Completion 2027-08-15
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT07087431

The ClinicalTrials.gov registry entry for NCT07087431 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (61% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which Immediate disclosure of CAD PRS results is the first listed.

NCT07087431 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07087431 about?

NCT07087431 is a clinical study titled "Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health". The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not cur...

What is the current status of trial NCT07087431?

This trial is currently recruiting. It is a NA study. The enrollment target is 500 participants. The study started on 2025-10-15. Estimated completion is 2027-08-15.

What conditions does trial NCT07087431 study?

This clinical trial studies the following conditions: Coronary Artery Disease.

What interventions are being tested in trial NCT07087431?

The interventions under investigation include: Immediate disclosure of CAD PRS results (BEHAVIORAL), Deferred Disclosure of CAD PRS results (BEHAVIORAL).

Who is sponsoring clinical trial NCT07087431?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07087431 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.