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NCT03447938 · ClinicalTrials.gov registry record · NA

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

A NA study of Coronary Artery Disease, sponsored by Ottawa Heart Institute Research Corporation.

Recruiting
Registry status
NA
Development phase
176
Enrollment target
13
Study locations

NCT03447938 is a NA study of Coronary Artery Disease that is actively recruiting participants, run by Ottawa Heart Institute Research Corporation. The registered enrollment target is 176 participants, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (86% lower). The trial reports 13 study locations across 9 states.

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The verdict

NCT03447938, a NA study of Coronary Artery Disease, is actively recruiting participants, sponsored by Ottawa Heart Institute Research Corporation.

RECRUITING
Registry status
NA
Development phase
176 participants
Enrollment target
13
Study locations

Study Summary

MICS CABG (Minimally invasive coronary surgery), where coronary artery bypass grafting (CABG) is completed through a small incision over the left chest, has evolved to become a safe and less invasive alternative to conventional sternotomy CABG. Several observational studies have suggested significantly shorter time to return to physical activity for MICS CABG patients compared to sternotomy CABG patients. A randomized study is warranted to validate these findings, provide higher level of evidence, and potentially lead to changes in practice. The MIST Trial is a multi-centre, prospective, open label, randomized control trial comparing quality of life and recovery in the early post-operative period, between patients undergoing MICS CABG versus patients undergoing sternotomy CABG. Patients referred for isolated CABG for multi-vessel coronary artery disease and deemed technically suitable for sternotomy CABG as well as for MICS CABG are considered for enrollment into the trial. Quality of life questionnaires (The SF-36, Seattle Angina Questionnaire and EQ-5D-5L) will be used to assess the quality of life and recovery in patients undergoing sternotomy CABG or MICS CABG at 1 month, 3 months, 6 months and 12 months follow up.

Conditions Studied

Coronary Artery Disease

Interventions

  • PROCEDURE MICS CABG
  • PROCEDURE Conventional CABG

Study Locations (13)

Other

  • Universitaire Ziekenhuizen Leuven - Leuven
  • Robert-Bosch-Hospital - Stuttgart
  • National University Hospital (NUH) - Singapore - Singapore
  • Far-Eastern Memorial Hospital - Taipei

Ontario

  • Division of Cardiac Surgery, University of Ottawa Heart Institute - Ottawa
  • University Health Network - Toronto

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Wisconsin

  • Gundersen Lutheran Medical Center - La Crosse

Jilin

  • Jilin Heart Hospital - Jilin

Saxony

  • Leipzig Heart Institute GmbH - Leipzig

Karnataka

  • Apollo Hospital, Bangalore - Bangalore

National Capital Territory of Delhi

  • Manipal Hospitals - New Delhi

Trial Details

FieldValue
Enrollment Target 176 participants
Start Date 2018-09-01
Est. Completion 2028-03-01
Phase NA

Sponsor

Ottawa Heart Institute Research Corporation

10 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03447938

The ClinicalTrials.gov registry entry for NCT03447938 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 176 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (86% lower). The listed sponsor is Ottawa Heart Institute Research Corporation, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which MICS CABG is the first listed.

NCT03447938 reports 13 study locations spanning 9 distinct geographic areas - top geographies include Other, Ontario, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03447938 about?

NCT03447938 is a clinical study titled "The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial". MICS CABG (Minimally invasive coronary surgery), where coronary artery bypass grafting (CABG) is completed through a small incision over the left chest, has evolved to become a safe and less invasive alternative to conventional sternotomy CABG. Several observational studies have suggested significan...

What is the current status of trial NCT03447938?

This trial is currently recruiting. It is a NA study. The enrollment target is 176 participants. The study started on 2018-09-01. Estimated completion is 2028-03-01.

What conditions does trial NCT03447938 study?

This clinical trial studies the following conditions: Coronary Artery Disease.

What interventions are being tested in trial NCT03447938?

The interventions under investigation include: MICS CABG (PROCEDURE), Conventional CABG (PROCEDURE).

Who is sponsoring clinical trial NCT03447938?

This trial is sponsored by Ottawa Heart Institute Research Corporation, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03447938 being conducted?

This trial has 13 study locations across Pennsylvania, Wisconsin, Ontario, Jilin, Saxony. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.