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Coronary Artery Disease: later-stage trial registry
57 of 220 indexed Coronary Artery Disease trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #42 of 28,707 conditions by registered trial count.
220 US clinical trials · 57 currently recruiting · #42 of 28,707 conditions by registered trial count
Coronary Artery Disease: 220 US clinical trials tracked, 57 recruiting.
Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.
Enrollment posture brief
Registry condition coronary-artery-disease
OPEN 57 | RECR 26% | LATE 42 | EARLY 15 | RANK #42 | SPON 17
Volume-matched condition peers
Nearest open-share peer: Adenocarcinoma (26% recruiting · 27 trials)
Coronary Artery Disease lists 57 open slots (26% of 220 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Coronary Artery Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Coronary Artery Disease is recruiting below its size-band peers.
57 of 220 indexed trials (25.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Coronary Artery Disease trials is spread across many organizations.
University of Florida accounts for 17 of 220 trials (7.7%). 134 distinct sponsors appear on at least one study for this condition label.
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Typical Coronary Artery Disease enrolment sits around 266 participants.
Median target enrolment is 266 among the 220 trials that report a genuine target (sentinel values excluded). 70 of those (31.8%) plan for fewer than 100 participants.
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Coronary Artery Disease splits between interventional and observational designs.
153 interventional and 67 observational studies make up this index (69.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
220 total, page 2 of 5
PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Johns Hopkins University
NCT05994014
Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability
University of Texas Southwestern Medical Center
NCT06047028
Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease
Georgia State University
NCT06994624
Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery
University of Iowa
NCT06207318
Evaluating Infrasonic Hemodynography
Scripps Health
NCT04636892
Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function
University of Florida
NCT04920799
Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy
University of Texas Southwestern Medical Center
NCT06814587
Database Registry of the Intermountain Heart Collaborative Study
Intermountain Health Care
NCT00406185
AI DErived Plaque Quantification: CCTA and AI-QCPA for Determining Effective CAD Management
HeartFlow
NCT06376851
Genomic Investigation of Cardiovascular Diseases
Scripps Translational Science Institute
NCT00722748
PRE-DETERMINE Cohort Study
Brigham and Women's Hospital
NCT01114269
Randomization of Single vs Multiple Arterial Grafts
Weill Medical College of Cornell University
NCT03217006
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD
University of Florida
NCT03417388
Mediators of Atherosclerosis in South Asians Living in America
University of California, San Francisco
NCT01207167
Firehawk Rapamycin Target Eluting Coronary Stent North American Trial
Shanghai MicroPort Medical (Group) Co.
NCT04562532
Precision PCI Registry
University of Florida
NCT06143709
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Stanford University
NCT07308860
Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
Abiomed
NCT04763200
Precise Procedural and PCI Plan (P4)
CoreAalst
NCT05253677
Century Trial, a Randomized Lifestyle Modification Study for Management of Stable Coronary Artery Disease
The University of Texas Health Science Center, Houston
NCT00756379
PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Beth Israel Deaconess Medical Center
NCT04093219
Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health
American College of Radiology
NCT06055972
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events
Novartis Pharmaceuticals
NCT05360446
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients
University of Sao Paulo General Hospital
NCT02338947
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
Bolt Medical
NCT06181240
Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease
Shockwave Medical
NCT05755711
Long Term Follow Up for CTSN Mitral Valve Repair Studies
Icahn School of Medicine at Mount Sinai
NCT03066050
The Precision CAD Trial
Emory University
NCT04755413
Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
Dana-Farber Cancer Institute
NCT04717050
XIENCE Skypoint Large Vessel Post Approval Study
Abbott Medical Devices
NCT05423379
Vis-Rx Prime Micro-Imaging Catheter Study
Gentuity
NCT06685783
Improvement Assessment of Coronary Flow Dysfunction Using Fundamental Fluid Dynamics
University of Cincinnati
NCT01719016
The Young Heart Study
Northwell Health
NCT04462159
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
Roswell Park Cancer Institute
NCT06029517
Intraoperative Echocardiography in Low-Risk CABG Surgery
University of Pennsylvania
NCT06154265
Short Interval Resveratrol Trial in Cardiovascular Surgery
MaineHealth
NCT03762096
Impact of Time Restricted Eating on Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation
University of California, San Diego
NCT05014880
The xDAPT External Validation Study
Icahn School of Medicine at Mount Sinai
NCT06736626
Patient Centered Machine Learning Model for Bleeding and Ischemic Risk
Abbott Medical Devices
NCT06089304
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
University of Colorado, Denver
NCT03973931
Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents
Cardiovascular Research Foundation, New York
NCT00638794
Physicians International Coronary Computed Tomography Angiography (CCTA) Utilization Registry
MDDX
NCT00932958
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
NYU Langone Health
NCT01471522
XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort)
Abbott Medical Devices
NCT01120379
Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
CardioDx
NCT00500617
Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)
Alexion Pharmaceuticals
NCT00088179
SPIRIT IV Clinical Trial: Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System
Abbott Medical Devices
NCT00307047
Improving Quality With Outpatient Decision Support
Agency for Healthcare Research and Quality (AHRQ)
NCT00225628
TC-WYRE: TAXUS Express Stent vs. Cypher Stent - What's Your Real Life Experience?
Boston Scientific Corporation
NCT00344630
Inclusive Invasive Physiological Assessment in Angina Syndromes Registry
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
NCT04485234
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 17 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Coronary Artery Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Coronary Artery Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Coronary Artery Disease page
220 registered trials, 57 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 57 Coronary Artery Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Coronary Artery Disease trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Coronary Artery Disease condition card totals 220 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.