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NCT05701358 · ClinicalTrials.gov registry record · NA

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

A NA study of Coronary Artery Disease and Acute Myocardial Infarction, sponsored by Population Health Research Institute.

Recruiting
Registry status
NA
Development phase
5,100
Enrollment target
20
Study locations

NCT05701358 is a NA study of Coronary Artery Disease and Acute Myocardial Infarction that is actively recruiting participants, run by Population Health Research Institute. The registered enrollment target is 5,100 participants, above the 1,264-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (303% higher). The trial reports 20 study locations across 12 states.

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The verdict

NCT05701358, a NA study of Coronary Artery Disease and Acute Myocardial Infarction, is actively recruiting participants, sponsored by Population Health Research Institute.

RECRUITING
Registry status
NA
Development phase
5,100 participants
Enrollment target
20
Study locations

Study Summary

COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI). COMPLETE-2 OCT is a large scale, prospective, multi-centre, observational, imaging study of patients with STEMI or NSTEMI and multivessel CAD in a subset of eligible COMPLETE-2 patients.

Conditions Studied

Coronary Artery Disease Acute Myocardial Infarction

Interventions

  • PROCEDURE Physiology-guided NCL PCI
  • PROCEDURE Angiography-guided NCL PCI

Study Locations (20)

Other

  • Klinik Floridsdorf - Vienna
  • William Osler Health System - Brampton
  • University of Alberta Hospital, Mazankowski Heart - Edmonton
  • Hamilton Health Sciences - Hamilton
  • Kingston Health Sciences Centre - Kingston

New York

  • Bassett Medical Center - Cooperstown
  • VA New York Harbor HealthCare System - New York
  • NYU Grossman School of Medicine - New York
  • Montefiore Medical Center - The Bronx

California

  • UCLA - Los Angeles
  • University of California, San Francisco - San Francisco

Kansas

  • Cardiovascular Research Institute of Kansas - Wichita

Maryland

  • The Johns Hopkins University School of Medicine - Baltimore

Michigan

  • University of Michigan - Ann Arbor

Minnesota

  • Metropolitan Cardiology Consultants / Metropolitan Heart and Vascular Institute (MCC/MHVI) - Coon Rapids

New Jersey

  • RWJ Barnabas Health - Jersey City

Trial Details

FieldValue
Enrollment Target 5,100 participants
Start Date 2023-06-22
Est. Completion 2028-06
Phase NA

Sponsor

Population Health Research Institute

21 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05701358

The ClinicalTrials.gov registry entry for NCT05701358 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 5,100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,264-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (303% higher). The listed sponsor is Population Health Research Institute, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which Physiology-guided NCL PCI is the first listed.

NCT05701358 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Other, New York, California.

Frequently Asked Questions

What is clinical trial NCT05701358 about?

NCT05701358 is a clinical study titled "Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease". COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardia...

What is the current status of trial NCT05701358?

This trial is currently recruiting. It is a NA study. The enrollment target is 5,100 participants. The study started on 2023-06-22. Estimated completion is 2028-06.

What conditions does trial NCT05701358 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Acute Myocardial Infarction.

What interventions are being tested in trial NCT05701358?

The interventions under investigation include: Physiology-guided NCL PCI (PROCEDURE), Angiography-guided NCL PCI (PROCEDURE).

Who is sponsoring clinical trial NCT05701358?

This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05701358 being conducted?

This trial has 20 study locations across California, Kansas, Maryland, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.