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NCT06713239 · ClinicalTrials.gov registry record · NA
A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD
A NA study of Coronary Artery Disease, sponsored by Cleerly.
- Recruiting
- Registry status
- NA
- Development phase
- 1,000
- Enrollment target
- 20
- Study locations
NCT06713239: Recruiting NA study of Coronary Artery Disease, sponsored by Cleerly.
NCT06713239 is a NA study of Coronary Artery Disease that is actively recruiting participants, run by Cleerly. The registered enrollment target is 1,000 participants, below the 1,282-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (22% lower). The trial reports 20 study locations across 16 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06713239, a NA study of Coronary Artery Disease, is actively recruiting participants, sponsored by Cleerly.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
PARAMOUNT is a prospective randomized open-label trial testing the hypothesis that a personalized management strategy in symptomatic patients with suspicion of coronary artery disease (CAD), using a CT-based coronary atherosclerotic plaque assessment by AI-enabled quantitative software improves: certainty for diagnosis of CAD, control of CAD risk factors and efficiency of ICA referral with appropriate PCI compared to the usual care strategy based on current AHA/ACC guidelines for care of symptomatic patients with suspicion of CAD.
Primary Outcome
The primary endpoint is composed of multuple elements, which are to be compared between Coronary Plaque-Based care and the usual care arm, in a hierarchical fashion, using the win ratio approach: 1\. Improved diagnostic certainty of CAD
Conditions Studied
Interventions
- DEVICE Cleerly Labs and Cleerly ISCHEMIA
Study Locations (20)
California
- Valiance Clinical Research- Huntington Park - Huntington Park
- Cardiovascular Institute of San Diego - San Diego
- Valiance Clinical Research- Tarzana - Tarzana
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center - Torrance
Florida
- Tampa Cardiovascular Interventions and Research - Tampa
- Flourish Research - Winter Park
Alabama
- Cardiology Associates of Mobile - Mobile
Colorado
- Intermountain Health Saint Joseph Hospital - Broomfield
Illinois
- Endeavor Health Clinical Operations - Evanston
Iowa
- MercyOne Des Moines Medical Center - West Des Moines
Kentucky
- Saint Elizabeth Medical Center - Edgewood
Louisiana
- Tulane University - New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2024-12-18 |
| Est. Completion | 2026-10 |
| Phase | NA |
What NCT06713239 shows while recruiting
NCT06713239 is an interventional study that assigns participants to a tested intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, below the 1,282-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (22% lower).
The record links to 1 condition, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which Cleerly Labs and Cleerly ISCHEMIA is the first listed.
NCT06713239 names 20 study sites across 16 states, led by California, Florida, Alabama.
Frequently Asked Questions
What is clinical trial NCT06713239 about?
NCT06713239 is a clinical study titled "A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD". PARAMOUNT is a prospective randomized open-label trial testing the hypothesis that a personalized management strategy in symptomatic patients with suspicion of coronary artery disease (CAD), using a CT-based coronary atherosclerotic plaque assessment by AI-enabled quantitative software improves: cer...
What is the current status of trial NCT06713239?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,000 participants. The study started on 2024-12-18. Estimated completion is 2026-10.
What conditions does trial NCT06713239 study?
This clinical trial studies the following conditions: Coronary Artery Disease.
What interventions are being tested in trial NCT06713239?
The interventions under investigation include: Cleerly Labs and Cleerly ISCHEMIA (DEVICE).
Who is sponsoring clinical trial NCT06713239?
This trial is sponsored by Cleerly, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06713239 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06713239's enrollment target sits among peer trials
1,000 46th of 219 higher than 171 of 219 other Coronary Artery Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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