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NCT07000045 · ClinicalTrials.gov registry record · NA

Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment

A NA study of Coronary Artery Disease and Coronary Calcification, sponsored by Annapoorna Kini.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT07000045 is a NA study of Coronary Artery Disease and Coronary Calcification that is actively recruiting participants, run by Annapoorna Kini. The registered enrollment target is 120 participants, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07000045, a NA study of Coronary Artery Disease and Coronary Calcification, is actively recruiting participants, sponsored by Annapoorna Kini.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The NODULE-SHOCK trial is a prospective, investigator-initiated, single-center, randomized controlled trial designed to compare the efficacy of intravascular lithotripsy (IVL) with or without rotational atherectomy (RA) in patients with coronary calcified nodules (Cohort A), and operator-determined vs maximum IVL pulses in patients with non-nodular severe coronary calcium (Cohort B).

Interventions

  • DEVICE Intravascular lithotripsy
  • DEVICE Rotational atherectomy

Study Locations (1)

New York

  • Mount Sinai Hospital - New York

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-10-06
Est. Completion 2027-12-31
Phase NA

Sponsor

Annapoorna Kini

3 total trials

What the Registry Record Tells You About NCT07000045

The ClinicalTrials.gov registry entry for NCT07000045 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (91% lower). The listed sponsor is Annapoorna Kini, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 2 interventions - of which Intravascular lithotripsy is the first listed.

NCT07000045 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT07000045 about?

NCT07000045 is a clinical study titled "Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment". The NODULE-SHOCK trial is a prospective, investigator-initiated, single-center, randomized controlled trial designed to compare the efficacy of intravascular lithotripsy (IVL) with or without rotational atherectomy (RA) in patients with coronary calcified nodules (Cohort A), and operator-determined ...

What is the current status of trial NCT07000045?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-10-06. Estimated completion is 2027-12-31.

What conditions does trial NCT07000045 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Coronary Calcification.

What interventions are being tested in trial NCT07000045?

The interventions under investigation include: Intravascular lithotripsy (DEVICE), Rotational atherectomy (DEVICE).

Who is sponsoring clinical trial NCT07000045?

This trial is sponsored by Annapoorna Kini, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07000045 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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