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NCT03886077 · ClinicalTrials.gov registry record
Study of Hepatitis Eradication Receiving Protease Inhibitor Administration
A clinical trial of Coronary Artery Disease and Morality, sponsored by Sentara Norfolk General Hospital.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT03886077: Recruiting study of Coronary Artery Disease and Morality, sponsored by Sentara Norfolk General Hospital.
NCT03886077 is a study of Coronary Artery Disease and Morality that is actively recruiting participants, run by Sentara Norfolk General Hospital. The registered enrollment target is 50 participants, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03886077, a study of Coronary Artery Disease and Morality, is actively recruiting participants, sponsored by Sentara Norfolk General Hospital.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective, non-blinded cohort study that will assess the safety, tolerability, and antiviral efficacy of glecaprevir/pibrentasivir therapy given post-discharge to HCV-negative recipients of HCV infected donors. Patients who meet entry criteria will be enrolled while on the transplant waitlist. At the time of transplant, some donors will be HCV positive / NAT positive and some will not be infected. Enrolled patients who receive an HCV negative donor will serve as contemporaneous controls. All study subjects who receive an HCV positive organ will be confirmed to have acquired HCV infection and genotype will be assessed prior to treatment with therapy.
Primary Outcome
12 weeks after the completion of drug that the patient no longer has Hepatitis C.
Conditions Studied
Interventions
- DRUG glecaprevir/pibrentasivir
Study Locations (1)
Virginia
- Sentara Norfolk General Hospital - Norfolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2019-03-20 |
| Est. Completion | 2024-12-31 |
What NCT03886077 shows while recruiting
NCT03886077 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,287-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which glecaprevir/pibrentasivir is the first listed.
NCT03886077 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT03886077 about?
NCT03886077 is a clinical study titled "Study of Hepatitis Eradication Receiving Protease Inhibitor Administration". This is a prospective, non-blinded cohort study that will assess the safety, tolerability, and antiviral efficacy of glecaprevir/pibrentasivir therapy given post-discharge to HCV-negative recipients of HCV infected donors. Patients who meet entry criteria will be enrolled while on the transplant wai...
What is the current status of trial NCT03886077?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2019-03-20. Estimated completion is 2024-12-31.
What conditions does trial NCT03886077 study?
This clinical trial studies the following conditions: Coronary Artery Disease, Morality.
What interventions are being tested in trial NCT03886077?
The interventions under investigation include: glecaprevir/pibrentasivir (DRUG).
Who is sponsoring clinical trial NCT03886077?
This trial is sponsored by Sentara Norfolk General Hospital, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03886077 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03886077's enrollment target sits among peer trials
50 179th of 219 higher than 39 of 219 other Coronary Artery Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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