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Cardiovascular Disease clinical trials
20 of 137 indexed Cardiovascular Disease trials are currently recruiting.
137 US clinical trials · 20 currently recruiting
Cardiovascular Disease is the subject of 137 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 10 of these trials.
The research picture
Cardiovascular Disease has 137 registered US clinical trials, 20 of them open to new participants right now, about 15% of the total.
- 20
- recruiting participants now
- 15%
- of trials open to enrollment
- 22
- in Phase 3–4 (later-stage)
- 10
- top sponsor: VA Office of Research and Development
Active & Recent Trials
137 total, page 3 of 3
Mindfulness, Yoga, and Cardiovascular Disease
The Cleveland Clinic
NCT00696852
Effects of Almonds on Cardiovascular Risk Factors
Penn State University
NCT01101230
Soybean Oil Trial of cArdiovascular Risk
USDA Beltsville Human Nutrition Research Center
NCT02404207
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
The Cleveland Clinic
NCT01817491
The Role of Nitric Oxide Synthase in Circulating Progenitor Cell Function
University of California, San Francisco
NCT00627068
Biomarker Guided Therapies in Stage A/B Heart Failure
VA Office of Research and Development
NCT02230891
Star-Close Early Ambulation Trial
Ernest Mazzaferri
NCT00590798
PCI Alternative Using Sustained Exercise
VA Office of Research and Development
NCT03520400
The Perceived Impact of Children s Risk Status for Hypertrophic Cardiomyopathy on Families: an Exploratory Study
National Human Genome Research Institute (NHGRI)
NCT01160536
Individual Variability to Aerobic Exercise Training
Western Colorado University
NCT02868710
Effects of Walnuts on Central Blood Pressure, Arterial Stiffness Indices, Lipoproteins, and Other CVD Risk Factors
Penn State University
NCT02210767
Exercise and Pioglitazone for HIV-Metabolic Syndromes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00639457
Quality Improvement and Personalization for Statins
VA Office of Research and Development
NCT02820870
Canola Oil Multicentre Intervention Trial (COMIT)
Penn State University
NCT01233778
Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)
University of Pennsylvania
NCT02187172
Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk
Penn State University
NCT02557334
The Fibrin Pad Cardiovascular Study
Ethicon
NCT01681030
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
The University of Texas Medical Branch, Galveston
NCT01869348
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Christos Mantzoros
NCT00525629
STEP AND GO: A Study of Technology-based Exercise Promotion
The University of Texas Medical Branch, Galveston
NCT01953224
Change of Fructose to Fat in South Asians
The Rogosin Institute
NCT01562782
Direct Measurements of Cardiometabolic Risk in Treated Schizophrenia Patients
Washington University School of Medicine
NCT00501163
MIcrovascular dysfuNction In Moderate-severe Psoriasis
Marcelo F. Di Carli, MD, FACC
NCT04271540
The Effect of Processed Tomato Products on CVD Risks
Penn State University
NCT00937742
Expression of Longevity Genes in Response to Extended Fasting
Intermountain Health Care
NCT01059760
Periodontal and Periapical Inflammation and Pregnancy
Roger Johnson
NCT00490165
Translating the Diabetes Prevention Program Into a Virtual Lifestyle Management Program
University of Pittsburgh
NCT00867425
Role of Vitamin D in Secondary Prevention of Cardiovascular Events
Creighton University
NCT01018849
Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome
University of Connecticut
NCT01411293
Healthy Fatty Acids in Transition
Penn State University
NCT00937963
The Effects Grapes on Health Indices
University of California, Davis
NCT01674231
A Study of Evacetrapib (LY2484595) in Participants With Severe Renal Impairment and in Healthy Participants
Eli Lilly and Company
NCT01825889
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Ohio State University
NCT02364570
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
University of Colorado, Denver
NCT02122198
Fructose-Induced Palmitate Synthesis in Overweight Subjects
Rockefeller University
NCT00535535
Fat Biology, Sleep Disorders, and Cardiovascular Disease
Mayo Clinic
NCT01229501
Trial of Oral Glutamine on Mitochondrial Function in CKD
University of Washington
NCT02838979
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 14 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiovascular Disease Trial Landscape
137 indexed Cardiovascular Disease studies · 20 recruiting (15%).
Phase mix: 22 late (III/IV) vs 15 early (I/II).
Top sponsor: VA Office of Research and Development (10 trials), 9 others listed. 37 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiovascular Disease?
PlainTrial tracks 137 US clinical trials for Cardiovascular Disease, of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiovascular Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.