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Cardiovascular Disease: full-pipeline trial registry
20 of 138 indexed Cardiovascular Disease trials are currently recruiting.
Corpus placement: #83 of 28,707 conditions by registered trial count.
138 US clinical trials · 20 currently recruiting · #83 of 28,707 conditions by registered trial count
Cardiovascular Disease: 138 US clinical trials tracked, 20 recruiting.
Cardiovascular Disease is the subject of 138 registered US clinical trials on ClinicalTrials.gov, 20 of them currently open to new participants. 22 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 10 of these trials.
Enrollment posture brief
Registry condition cardiovascular-disease
OPEN 20 | RECR 14% | LATE 22 | EARLY 15 | RANK #83 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Acute Coronary Syndrome (15% recruiting · 41 trials)
Cardiovascular Disease lists 20 open slots (14% of 138 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cardiovascular Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cardiovascular Disease is recruiting below its size-band peers.
20 of 138 indexed trials (14.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cardiovascular Disease trials is spread across many organizations.
VA Office of Research and Development accounts for 10 of 138 trials (7.2%). 84 distinct sponsors appear on at least one study for this condition label.
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Typical Cardiovascular Disease enrolment sits around 120 participants.
Median target enrolment is 120 among the 138 trials that report a genuine target (sentinel values excluded). 59 of those (42.8%) plan for fewer than 100 participants.
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Cardiovascular Disease splits between interventional and observational designs.
93 interventional and 45 observational studies make up this index (67.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
138 total, page 3 of 3
PREVENT Tool Study: Late Effects Clinic
Washington University School of Medicine
NCT04530825
Mindfulness, Yoga, and Cardiovascular Disease
The Cleveland Clinic
NCT00696852
Effects of Almonds on Cardiovascular Risk Factors
Penn State University
NCT01101230
Soybean Oil Trial of cArdiovascular Risk
USDA Beltsville Human Nutrition Research Center
NCT02404207
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
The Cleveland Clinic
NCT01817491
The Role of Nitric Oxide Synthase in Circulating Progenitor Cell Function
University of California, San Francisco
NCT00627068
Biomarker Guided Therapies in Stage A/B Heart Failure
VA Office of Research and Development
NCT02230891
Star-Close Early Ambulation Trial
Ernest Mazzaferri
NCT00590798
PCI Alternative Using Sustained Exercise
VA Office of Research and Development
NCT03520400
The Perceived Impact of Children s Risk Status for Hypertrophic Cardiomyopathy on Families: an Exploratory Study
National Human Genome Research Institute (NHGRI)
NCT01160536
Individual Variability to Aerobic Exercise Training
Western Colorado University
NCT02868710
Effects of Walnuts on Central Blood Pressure, Arterial Stiffness Indices, Lipoproteins, and Other CVD Risk Factors
Penn State University
NCT02210767
Exercise and Pioglitazone for HIV-Metabolic Syndromes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00639457
Quality Improvement and Personalization for Statins
VA Office of Research and Development
NCT02820870
Canola Oil Multicentre Intervention Trial (COMIT)
Penn State University
NCT01233778
Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)
University of Pennsylvania
NCT02187172
Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk
Penn State University
NCT02557334
The Fibrin Pad Cardiovascular Study
Ethicon
NCT01681030
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
The University of Texas Medical Branch, Galveston
NCT01869348
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Christos Mantzoros
NCT00525629
STEP AND GO: A Study of Technology-based Exercise Promotion
The University of Texas Medical Branch, Galveston
NCT01953224
Change of Fructose to Fat in South Asians
The Rogosin Institute
NCT01562782
Direct Measurements of Cardiometabolic Risk in Treated Schizophrenia Patients
Washington University School of Medicine
NCT00501163
MIcrovascular dysfuNction In Moderate-severe Psoriasis
Marcelo F. Di Carli, MD, FACC
NCT04271540
The Effect of Processed Tomato Products on CVD Risks
Penn State University
NCT00937742
Expression of Longevity Genes in Response to Extended Fasting
Intermountain Health Care
NCT01059760
Periodontal and Periapical Inflammation and Pregnancy
Roger Johnson
NCT00490165
Translating the Diabetes Prevention Program Into a Virtual Lifestyle Management Program
University of Pittsburgh
NCT00867425
Role of Vitamin D in Secondary Prevention of Cardiovascular Events
Creighton University
NCT01018849
Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome
University of Connecticut
NCT01411293
Healthy Fatty Acids in Transition
Penn State University
NCT00937963
The Effects Grapes on Health Indices
University of California, Davis
NCT01674231
A Study of Evacetrapib (LY2484595) in Participants With Severe Renal Impairment and in Healthy Participants
Eli Lilly and Company
NCT01825889
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Ohio State University
NCT02364570
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
University of Colorado, Denver
NCT02122198
Fructose-Induced Palmitate Synthesis in Overweight Subjects
Rockefeller University
NCT00535535
Fat Biology, Sleep Disorders, and Cardiovascular Disease
Mayo Clinic
NCT01229501
Trial of Oral Glutamine on Mitochondrial Function in CKD
University of Washington
NCT02838979
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 14 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Cardiovascular Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cardiovascular Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cardiovascular Disease page
138 registered trials, 20 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 20 Cardiovascular Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Cardiovascular Disease trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Disease condition card totals 138 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.