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NCT00525629 · ClinicalTrials.gov registry record · NA
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
A NA study of Type 2 Diabetes and Cardiovascular Disease, sponsored by Christos Mantzoros.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT00525629: Completed NA study of Type 2 Diabetes and Cardiovascular Disease, sponsored by Christos Mantzoros.
NCT00525629 is a NA study of Type 2 Diabetes and Cardiovascular Disease that has completed, run by Christos Mantzoros. The registered enrollment target is 40 participants, below the 3,924-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00525629, a NA study of Type 2 Diabetes and Cardiovascular Disease, has completed, sponsored by Christos Mantzoros.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Walnuts include many potentially beneficial micronutrients and phytochemicals, in this study we propose to examine the effects of walnuts independent of macronutrient content. The purpose of this proposal is to study in depth the short-term effects of walnut consumption in men and women with the metabolic syndrome. Study Aim 1: To investigate the effects of walnuts (48gms per day over 3 days) on insulin resistance in subjects with the metabolic syndrome. Study Aim 2: To investigate the effects of 48gms per day of walnuts over 3 days on lipids and inflammatory markers. Study Aim 3: To assess the possible mechanisms of the biological effects of short-term walnut consumption through assessment of adipokines, resting metabolic rate, gene expression in white blood cells and the effect of walnuts when consumed as part of a mixed meal, on glucose excursions, insulin secretion and the excretion of gut peptides and free fatty acids.
Primary Outcome
HOMA-IR (homeostatic model assessment of insulin resistance) given in units as it is a ratio equation.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Walnuts
- DIETARY_SUPPLEMENT Control
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2007-02 |
| Est. Completion | 2008-12 |
| Phase | NA |
What the finished NCT00525629 record still lists
NCT00525629 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 3,924-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Type 2 Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Walnuts is the first listed.
NCT00525629 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00525629 about?
NCT00525629 is a clinical study titled "The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome". Walnuts include many potentially beneficial micronutrients and phytochemicals, in this study we propose to examine the effects of walnuts independent of macronutrient content. The purpose of this proposal is to study in depth the short-term effects of walnut consumption in men and women with the met...
What is the current status of trial NCT00525629?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2007-02. Estimated completion is 2008-12.
What conditions does trial NCT00525629 study?
This clinical trial studies the following conditions: Type 2 Diabetes, Cardiovascular Disease, Metabolic Syndrome.
What interventions are being tested in trial NCT00525629?
The interventions under investigation include: Walnuts (DIETARY_SUPPLEMENT), Control (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00525629?
This trial is sponsored by Christos Mantzoros, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00525629 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00525629's enrollment target sits among peer trials
40 231st of 327 higher than 88 of 327 other Type 2 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 2 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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