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NCT00490165 · ClinicalTrials.gov registry record

Periodontal and Periapical Inflammation and Pregnancy

A clinical trial of Diabetes and Pregnancy, sponsored by Roger Johnson.

Completed
Registry status
30
Enrollment target
1
Study location

NCT00490165: Completed study of Diabetes and Pregnancy, sponsored by Roger Johnson.

NCT00490165 is a study of Diabetes and Pregnancy that has completed, run by Roger Johnson. The registered enrollment target is 30 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00490165, a study of Diabetes and Pregnancy, has completed, sponsored by Roger Johnson.

COMPLETED
Registry status
30 participants
Enrollment target
1
Study location

Study Summary

This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study. Recent animal studies we conducted showed that periapical abscesses during pregnancy cause a systemic inflammatory response in the mother. Also due to the increase in TNF-alpha (an inflammatory cytokine) the mother also become insulin resistant and thus developed gestational diabetes. Periodontal inflammation has been shown in the research to lead to low-birth weight and pre-term birth. We are looking retrospectively to see if an association exists in charted data between periapical and periodontal inflammation and adverse pregnancy outcomes.

Study Locations (1)

Mississippi

  • University of Mississippi Medical Center - Jackson

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2007-03
Est. Completion 2011-12
Roger Johnson

1 total trials

What the finished NCT00490165 record still lists

NCT00490165 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (99% lower).

The record links to 6 conditions, with Diabetes appearing as the primary indexed condition, and to 0 interventions.

NCT00490165 reports a single indexed study location in Mississippi.

Frequently Asked Questions

What is clinical trial NCT00490165 about?

NCT00490165 is a clinical study titled "Periodontal and Periapical Inflammation and Pregnancy". This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study. Recent animal studies we conducted showed that periapical abscesses during pregnancy cause a systemic inflammatory response in the mother. ...

What is the current status of trial NCT00490165?

This trial is currently completed. The enrollment target is 30 participants. The study started on 2007-03. Estimated completion is 2011-12.

What conditions does trial NCT00490165 study?

This clinical trial studies the following conditions: Diabetes, Pregnancy, Cardiovascular Disease, Dental Caries, Periodontal Disease.

Who is sponsoring clinical trial NCT00490165?

This trial is sponsored by Roger Johnson, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00490165 being conducted?

This trial has 1 study location across Mississippi. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Diabetes

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00490165's enrollment target sits among peer trials

30 281st of 338 higher than 51 of 338 other Diabetes trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00490165, the US trial registry maintained by the National Library of Medicine. NCT00490165 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.