Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Acute Coronary Syndrome: full-pipeline trial registry
6 of 41 indexed Acute Coronary Syndrome trials are currently recruiting.
Corpus placement: #357 of 28,707 conditions by registered trial count.
41 US clinical trials · 6 currently recruiting · #357 of 28,707 conditions by registered trial count
Acute Coronary Syndrome: 41 US clinical trials tracked, 6 recruiting.
Acute Coronary Syndrome is the subject of 41 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Hennepin Healthcare Research Institute, running 4 of these trials.
Enrollment posture brief
Registry condition acute-coronary-syndrome
OPEN 6 | RECR 15% | LATE 7 | EARLY 8 | RANK #357 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Dry Eye Disease (15% recruiting · 34 trials)
Acute Coronary Syndrome lists 6 open slots (15% of 41 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Acute Coronary Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Acute Coronary Syndrome is recruiting below its size-band peers.
6 of 41 indexed trials (14.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Acute Coronary Syndrome trials is spread across many organizations.
Hennepin Healthcare Research Institute accounts for 4 of 41 trials (9.8%). 30 distinct sponsors appear on at least one study for this condition label.
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Typical Acute Coronary Syndrome enrolment sits around 500 participants.
Median target enrolment is 500 among the 41 trials that report a genuine target (sentinel values excluded). 9 of those (22%) plan for fewer than 100 participants.
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Acute Coronary Syndrome splits between interventional and observational designs.
27 interventional and 14 observational studies make up this index (65.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
41 total, page 1 of 1
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals
NCT05918861
A Polypill for Acute Coronary Syndrome
University of Texas Southwestern Medical Center
NCT07032389
AngelMed Guardian® System PMA Post Approval Study
Angel Medical Systems
NCT05412927
Positive Emotions Following Acute Cardiac Events
Massachusetts General Hospital
NCT05412862
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
University of Minnesota
NCT05426083
A Prospective Research Investigation of Ischemia Using MCG
SB Technology
NCT06481943
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Janssen Research & Development
NCT05754957
COmparisoN of High-sensitivity Cardiac TRoponin I and T ASsays Trial
Hennepin Healthcare Research Institute
NCT03214029
MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.
Hennepin Healthcare Research Institute
NCT05853042
LEADERS FREE II: BioFreedom™ Pivotal Study
Biosensors Europe
NCT02843633
Post Acute Cardiac Event Smoking (PACES) Study
Hennepin Healthcare Research Institute
NCT03413423
Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)
Wake Forest University Health Sciences
NCT04617834
Online Tai Chi Plus Fitbit After ACS
Beth Israel Deaconess Medical Center
NCT05699642
Healthy Heart Habits-2
The Miriam Hospital
NCT06440278
OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
Svelte Medical Systems
NCT03716102
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
AstraZeneca
NCT00391872
An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00809965
HEART Pathway Implementation
Wake Forest University Health Sciences
NCT02056964
Treatment With Adenosine Diphosphate (ADP) Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome
Eli Lilly and Company
NCT01088503
Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide)
Sanofi
NCT01147250
ECG Methods for the Prompt Identification of Coronary Events
University of Pittsburgh
NCT04237688
GRAVITAS: Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety
Accumetrics
NCT00645918
Safety and Efficacy of TAK-442 in Subjects With Acute Coronary Syndromes
Takeda
NCT00677053
5th Generation cTnT in ED ACS
Columbia University
NCT03590535
Pharmacist Intervention to Decrease Medication Errors in Heart Disease Patients (The PILL-CVD Study)
Vanderbilt University Medical Center
NCT00632021
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
GlaxoSmithKline
NCT00910962
PARA-HEART Pilot Implementation
Wake Forest University Health Sciences
NCT02709135
Safety and Efficacy Iodofiltic Acid I 123 in the Treatment of Acute Coronary Syndrome
Molecular Insight Pharmaceuticals
NCT00514501
Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention
University of Pennsylvania
NCT02508116
Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome
Novartis Pharmaceuticals
NCT04873934
Rule Out Myocardial Infarction by Computer Assisted Tomography
Massachusetts General Hospital
NCT00990262
Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety
Massachusetts General Hospital
NCT03118752
Comparison of Depression Interventions After Acute Coronary Syndrome
Columbia University
NCT01032018
Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain
Wake Forest University Health Sciences
NCT00678639
Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients
Genetesis
NCT03255772
The Effect of Reloading Prasugrel in a Patient Who Has Already Received a Loading Dose (LD) of Clopidogrel
Medstar Health Research Institute
NCT01365221
Mind-body Interventions in Cardiac Patients
Massachusetts General Hospital
NCT01270568
A Study to Evaluate the Effect of Losmapimod on Cardiac Conduction as Compared to Placebo and Moxifloxacin
GlaxoSmithKline
NCT01756495
Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation
CirQuest Labs
NCT03746782
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
University of North Carolina, Chapel Hill
NCT04131816
Healthy Heart Habits
Hennepin Healthcare Research Institute
NCT04158219
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 6 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Acute Coronary Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Acute Coronary Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Acute Coronary Syndrome page
41 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Acute Coronary Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Hennepin Healthcare Research Institute sponsors the most Acute Coronary Syndrome trials on record, review their full trial history before evaluating a specific study. See Hennepin Healthcare Research Institute's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Coronary Syndrome condition card totals 41 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.