Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Acute Coronary Syndrome
Open-data reference.
41 US clinical trials · 6 currently recruiting
Active & Recent Trials
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals
NCT05918861
A Polypill for Acute Coronary Syndrome
University of Texas Southwestern Medical Center
NCT07032389
AngelMed Guardian® System PMA Post Approval Study
Angel Medical Systems
NCT05412927
Positive Emotions Following Acute Cardiac Events
Massachusetts General Hospital
NCT05412862
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
University of Minnesota
NCT05426083
A Prospective Research Investigation of Ischemia Using MCG
SB Technology
NCT06481943
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Janssen Research & Development
NCT05754957
COmparisoN of High-sensitivity Cardiac TRoponin I and T ASsays Trial
Hennepin Healthcare Research Institute
NCT03214029
MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.
Hennepin Healthcare Research Institute
NCT05853042
LEADERS FREE II: BioFreedom™ Pivotal Study
Biosensors Europe
NCT02843633
Post Acute Cardiac Event Smoking (PACES) Study
Hennepin Healthcare Research Institute
NCT03413423
Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)
Wake Forest University Health Sciences
NCT04617834
Online Tai Chi Plus Fitbit After ACS
Beth Israel Deaconess Medical Center
NCT05699642
Healthy Heart Habits-2
The Miriam Hospital
NCT06440278
OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
Svelte Medical Systems
NCT03716102
A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome
AstraZeneca
NCT00391872
An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00809965
HEART Pathway Implementation
Wake Forest University Health Sciences
NCT02056964
Treatment With Adenosine Diphosphate (ADP) Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome
Eli Lilly and Company
NCT01088503
Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide)
Sanofi
NCT01147250
ECG Methods for the Prompt Identification of Coronary Events
University of Pittsburgh
NCT04237688
GRAVITAS: Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety
Accumetrics
NCT00645918
Safety and Efficacy of TAK-442 in Subjects With Acute Coronary Syndromes
Takeda
NCT00677053
5th Generation cTnT in ED ACS
Columbia University
NCT03590535
Pharmacist Intervention to Decrease Medication Errors in Heart Disease Patients (The PILL-CVD Study)
Vanderbilt University Medical Center
NCT00632021
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
GlaxoSmithKline
NCT00910962
PARA-HEART Pilot Implementation
Wake Forest University Health Sciences
NCT02709135
Safety and Efficacy Iodofiltic Acid I 123 in the Treatment of Acute Coronary Syndrome
Molecular Insight Pharmaceuticals
NCT00514501
Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention
University of Pennsylvania
NCT02508116
Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome
Novartis Pharmaceuticals
NCT04873934
Rule Out Myocardial Infarction by Computer Assisted Tomography
Massachusetts General Hospital
NCT00990262
Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety
Massachusetts General Hospital
NCT03118752
Comparison of Depression Interventions After Acute Coronary Syndrome
Columbia University
NCT01032018
Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain
Wake Forest University Health Sciences
NCT00678639
Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients
Genetesis
NCT03255772
The Effect of Reloading Prasugrel in a Patient Who Has Already Received a Loading Dose (LD) of Clopidogrel
Medstar Health Research Institute
NCT01365221
Mind-body Interventions in Cardiac Patients
Massachusetts General Hospital
NCT01270568
A Study to Evaluate the Effect of Losmapimod on Cardiac Conduction as Compared to Placebo and Moxifloxacin
GlaxoSmithKline
NCT01756495
Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation
CirQuest Labs
NCT03746782
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
University of North Carolina, Chapel Hill
NCT04131816
Healthy Heart Habits
Hennepin Healthcare Research Institute
NCT04158219
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 6 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Acute Coronary Syndrome Trial Landscape
ClinicalTrials.gov lists 41 US studies indexed under Acute Coronary Syndrome, and 6 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Acute Coronary Syndrome shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Acute Coronary Syndrome is led by Hennepin Healthcare Research Institute with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 41 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Acute Coronary Syndrome?
PlainTrial tracks 41 US clinical trials for Acute Coronary Syndrome, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Acute Coronary Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.