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NCT03520400 · ClinicalTrials.gov registry record · NA
PCI Alternative Using Sustained Exercise
A NA study of Cardiovascular Disease, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 51
- Enrollment target
- 1
- Study location
NCT03520400: Completed NA study of Cardiovascular Disease, sponsored by VA Office of Research and Development.
NCT03520400 is a NA study of Cardiovascular Disease that has completed, run by VA Office of Research and Development. The registered enrollment target is 51 participants, below the 2,697-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03520400, a NA study of Cardiovascular Disease, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 51 participants
- Enrollment target
- 1
- Study location
Study Summary
Cardiovascular disease remains the leading cause of morbidity and mortality in the U.S. and is a major cause of disability in Veterans. Most of these deaths are due to coronary artery disease (CAD). The most common treatment for CAD is revascularization, an invasive procedure which usually involves placing a stent inside an artery that is diseased. However, exercise training is often overlooked because clinicians tend to focus on repairing the coronary circulation and the potential need for revascularization. Studies have shown that exercise training can be effective for patients with CAD and that it saves costs. In this study, invasive revascularization will be compared to a structured program of exercise training over one year. Comparisons will be made between groups for symptoms, coronary artery size and function using PET/CTA, and health care cost utilization.
Primary Outcome
Measurement of myocardial blood flow has only been analyzed at baseline at this time. Intravenous 13NH3 will be used as the flow tracer and serial imaging with PET will be performed. Measurements will be performed at baseline, and after pharmacologic stress with dipyridamole. Myocardial blood flow at rest and following dipyridamole infusion will be expressed as ml flow/100 g/min. The myocardial perfusion reserve will be calculated as the ratio of the myocardial blood flow during stress (e.g. aft
Conditions Studied
Interventions
- BEHAVIORAL Exercise Therapy
Study Locations (1)
California
- VA Palo Alto Health Care System, Palo Alto, CA - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2012-10-01 |
| Est. Completion | 2019-09-30 |
| Phase | NA |
What the finished NCT03520400 record still lists
NCT03520400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 2,697-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Cardiovascular Disease appearing as the primary indexed condition, and to 1 intervention - of which Exercise Therapy is the first listed.
NCT03520400 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03520400 about?
NCT03520400 is a clinical study titled "PCI Alternative Using Sustained Exercise". Cardiovascular disease remains the leading cause of morbidity and mortality in the U.S. and is a major cause of disability in Veterans. Most of these deaths are due to coronary artery disease (CAD). The most common treatment for CAD is revascularization, an invasive procedure which usually involves ...
What is the current status of trial NCT03520400?
This trial is currently completed. It is a NA study. The enrollment target is 51 participants. The study started on 2012-10-01. Estimated completion is 2019-09-30.
What conditions does trial NCT03520400 study?
This clinical trial studies the following conditions: Cardiovascular Disease.
What interventions are being tested in trial NCT03520400?
The interventions under investigation include: Exercise Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT03520400?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03520400 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03520400's enrollment target sits among peer trials
51 107th of 137 higher than 31 of 137 other Cardiovascular Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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