Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Breast Cancer: early-phase trial registry
423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1 of 28,707 conditions by registered trial count.
1,251 US clinical trials · 423 currently recruiting · #1 of 28,707 conditions by registered trial count
Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.
Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.
Enrollment posture brief
Registry condition breast-cancer
OPEN 423 | RECR 34% | LATE 120 | EARLY 491 | RANK #1 | SPON 98
Volume-matched condition peers
Nearest open-share peer: Refractory Multiple Myeloma (34% recruiting · 68 trials)
Breast Cancer lists 423 open slots (34% of 1,251 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Breast Cancer is recruiting below its size-band peers.
423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Breast Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.
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Typical Breast Cancer enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.
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Breast Cancer research is mostly interventional.
1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,251 total, page 20 of 26
Evaluation of Breast CT
University of California, Davis
NCT00584233
Nipple Sparing Mastectomy - Cosmetic Outcomes
Wake Forest University Health Sciences
NCT01002014
Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status
Stanford University
NCT00383500
A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors
Pfizer
NCT04672460
Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors
Indiana University
NCT03712813
Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors
University of Vermont
NCT01482702
Protocol for Women at Increased Risk of Developing Breast Cancer
Carol Fabian, MD
NCT00291694
Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer
HealthPartners Institute
NCT00202059
ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases
Angiochem
NCT02048059
Intra-operative Digital vs. Standard Mammography
Massachusetts General Hospital
NCT01766102
A Comprehensive Oncology Rehabilitation and Exercise (CORE) Program Among Breast Cancer Survivors
University of Utah
NCT04594473
A Study of PI3-Kinase Inhibitor GDC-0941 in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole, in Participants With Locally Recurrent or Metastatic Breast Cancer
Genentech
NCT00960960
Phase II Trial of EVEROLIMUS ± Trastuzumab in Hormone-Refractory Metastatic Breast Cancer
Emory University
NCT00912340
A Study of LY353381 (Arzoxifene) for Patients Who Benefitted From This Drug in Other Oncology Trials and Wished to Continue Treatment
Eli Lilly and Company
NCT00190697
Paclitaxel With or Without PSC 833 in Treating Patients With Metastatic Breast Cancer
City of Hope Medical Center
NCT00002937
Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection
GE Healthcare
NCT00918281
Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Breast Cancer
Nektar Therapeutics
NCT00802945
Paclitaxel, Trastuzumab, and Pertuzumab in the Treatment of Metastatic HER2-Positive Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT01276041
Study of Concurrent Paclitaxel and Radiation: Correlation of Tumor Profiles With Pathologic Response
NYU Langone Health
NCT02280252
Nutrition, Physical Activity, and Cognition in Breast Cancer Survivors
Texas State University, San Marcos
NCT02591316
Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab
Abramson Cancer Center at Penn Medicine
NCT04023110
Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
Duke University
NCT03719495
Tissue Procurement Protocol for Patients Undergoing Neoadjuvant Systemic Therapy for Breast Cancer
University of Michigan Rogel Cancer Center
NCT00161265
Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density
NCIC Clinical Trials Group
NCT00238316
Promoting a Healthier Lifestyle Among Breast Cancer Survivors
H. Lee Moffitt Cancer Center and Research Institute
NCT01419613
Development of a Clinical Trial Specific Question Prompt List
Memorial Sloan Kettering Cancer Center
NCT00662324
Effect of Radiotherapy Variables on Circulating Effectors of Immune Response and Local Microbiome
Weill Medical College of Cornell University
NCT03383107
Lapatinib and Trastuzumab With or Without Endocrine Therapy
Baylor Breast Care Center
NCT00548184
Phase II Study of Intra-Operative Electron Irradiation and External Beam Irradiation After Lumpectomy in Patients With T1N0M0 and T2N0M0 Breast Cancer
Mayo Clinic
NCT01215162
Oral STAT3 Inhibitor, TTI-101, in Patients with Advanced Cancers
Tvardi Therapeutics, Incorporated
NCT03195699
Electronic Xoft Intersociety Brachytherapy Trial: Electronic Brachytherapy (EBT) For Treatment of Early Stage Breast Cancer
Xoft
NCT00742222
Electro-acupuncture for the Prevention of Taxane Induced Myalgias and Neuropathy
Columbia University
NCT01163682
Pilot Study of a Pharmacy Intervention for Older Adults With Cancer
Massachusetts General Hospital
NCT02871115
Feasibility of Implementing Acupuncture Into Federally Qualified Health Center Among Breast Cancer Survivors
University of Illinois at Chicago
NCT05615753
Automated Pain Intervention for Underserved Minority Breast Cancer Patients
M.D. Anderson Cancer Center
NCT00881010
Sentinel Lymph Node Biopsy and Primary Tumor Gene Expression Profiling in Finding Axillary Lymph Node Metastases in Women Who Have Received Neoadjuvant Therapy for Stage II, Stage III, or Stage IV Breast Cancer
National Institutes of Health Clinical Center (CC)
NCT00080860
The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function
Carl Ade, M.S., Ph.D.
NCT03062878
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
Mayo Clinic
NCT00436917
Tipifarnib and Combination Chemotherapy in Treating Patients With Stage II or Stage III Breast Cancer
National Cancer Institute (NCI)
NCT00470301
Omega-3 Fatty Acid in Treating Pain in Patients With Breast or Ovarian Cancer Receiving Paclitaxel
New Mexico Cancer Research Alliance
NCT01821833
Computer-Based Comprehensive Geriatric Assessment in Oncology for Individuals 70 or Older With Gastrointestinal Malignancies
Dana-Farber Cancer Institute
NCT00973440
LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer
Alliance for Clinical Trials in Oncology
NCT00006007
Vaccination of High Risk Breast Cancer Patients
University of Arkansas
NCT02229084
DC Vaccine for Patients With Ductal Carcinoma In Situ
Abramson Cancer Center at Penn Medicine
NCT02061332
Acupressure in Treating Nausea in Women Receiving Combination Chemotherapy for Breast Cancer
M.D. Anderson Cancer Center
NCT00046865
Cytoxan, Epirubicin and Capecitabine in Women With Breast Cancer
Craig A. Bunnell, MD, MPH
NCT00146588
Epothilone B in Treating Patients With CNS Metastases From Breast Cancer
David Peereboom, MD
NCT00450866
Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2
National Institutes of Health Clinical Center (CC)
NCT00019812
Treating Cancer-Related Fatigue Through Systematic Light Exposure
Icahn School of Medicine at Mount Sinai
NCT01873794
Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant
Fred Hutchinson Cancer Center
NCT00410657
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 235 |
| Phase 2 | 256 |
| Phase 3 | 100 |
| Phase 4 | 20 |
Top Sponsors
Named interventions
Most-linked intervention names on Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Breast Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Breast Cancer page
1,251 registered trials, 423 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 423 Breast Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Breast Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer condition card totals 1,251 registered trials; most-linked intervention Fulvestrant; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.