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NCT02061332 · ClinicalTrials.gov registry record · Phase 1

DC Vaccine for Patients With Ductal Carcinoma In Situ

A Phase 1 study of Breast Cancer and DCIS, sponsored by Abramson Cancer Center at Penn Medicine.

Completed
Registry status
Phase 1
Development phase
58
Enrollment target
1
Study location

NCT02061332: Completed Phase 1 study of Breast Cancer and DCIS, sponsored by Abramson Cancer Center at Penn Medicine.

NCT02061332 is a Phase 1 study of Breast Cancer and DCIS that has completed, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 58 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02061332, a Phase 1 study of Breast Cancer and DCIS, has completed, sponsored by Abramson Cancer Center at Penn Medicine.

COMPLETED
Registry status
Phase 1
Development phase
58 participants
Enrollment target
1
Study location

Study Summary

Women who are diagnosed with Her-2/neu over-expressing DCIS will receive DC1 vaccines by intranodal, intralesional, or both routes of administration. The primary objective will be safety and administration with secondary objectives of immune activation and clinical response.

Primary Outcome

Blood pressure will be obtained just prior to the vaccination then, every 15 minutes for the first hour after the dose is given.

Conditions Studied

Interventions

  • BIOLOGICAL HER-2 Pulsed Dendritic cell Vaccine

Study Locations (1)

Pennsylvania

  • Hospital of the University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2009-07
Est. Completion 2015-10-07
Phase Phase 1

What the finished NCT02061332 record still lists

NCT02061332 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which HER-2 Pulsed Dendritic cell Vaccine is the first listed.

NCT02061332 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT02061332 about?

NCT02061332 is a clinical study titled "DC Vaccine for Patients With Ductal Carcinoma In Situ". Women who are diagnosed with Her-2/neu over-expressing DCIS will receive DC1 vaccines by intranodal, intralesional, or both routes of administration. The primary objective will be safety and administration with secondary objectives of immune activation and clinical response.

What is the current status of trial NCT02061332?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 58 participants. The study started on 2009-07. Estimated completion is 2015-10-07.

What conditions does trial NCT02061332 study?

This clinical trial studies the following conditions: Breast Cancer, DCIS.

What interventions are being tested in trial NCT02061332?

The interventions under investigation include: HER-2 Pulsed Dendritic cell Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02061332?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02061332 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02061332's enrollment target sits among peer trials

58 761st of 1224 higher than 461 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02061332, the US trial registry maintained by the National Library of Medicine. NCT02061332 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.