Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 423 recruiting now early-phase tilt #1 of 28,963 conditions

Breast Cancer: early-phase trial registry

423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1 of 28,963 conditions by registered trial count.

1,251 US clinical trials · 423 currently recruiting · #1 of 28,963 conditions by registered trial count

Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.

Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.

Open enrollment, early-phase tilt

Breast Cancer has 1,251 registered US clinical trials, 423 of them open to new participants right now, about 34% of the total.

423
recruiting participants now
34%
of trials open to enrollment
120
in Phase 3-4 (later-stage)
98
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #1 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer is recruiting below its size-band peers.

    423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Cancer enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.

  4. Breast Cancer research is mostly interventional.

    1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1235Phase 2256Phase 3100Phase 420

Open and recent trials

1,251 total, page 19 of 26

COMPLETED NA 107 participants

A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer

Memorial Sloan Kettering Cancer Center

NCT00984321

COMPLETED Phase 1 107 participants

Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients

Novartis Pharmaceuticals

NCT01068483

COMPLETED NA 106 participants

Non-Hormonal Vaginal Moisturizer in Hormone-Receptor Positive Postmenopausal Cancer Survivors Experiencing Estrogen Deprivation Symptoms on Vulvovaginal Health

Memorial Sloan Kettering Cancer Center

NCT01738152

COMPLETED Phase 1 105 participants

A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors

Syros Pharmaceuticals

NCT04247126

COMPLETED Phase 1 105 participants

Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast Cancer

Puma Biotechnology

NCT00741260

COMPLETED Phase 2 104 participants

A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Participants With Advanced Breast Cancer

Eisai

NCT00879086

COMPLETED Phase 1 104 participants

Cone Beam Computed Tomography for Breast Imaging

Koning Corporation

NCT00972413

COMPLETED Phase 2 102 participants

Doxorubicin HCI Liposome Injection Versus Weekly Docetaxel in Patients First Relapse Metastatic Breast Cancer

SCRI Development Innovations

NCT00193037

COMPLETED NA 102 participants

Comparing (SIS.NET) to Standard Care in Patients Who Have Completed the Acute Phase of Treatment for Early Breast Cancer

University of California, San Francisco

NCT01308775

COMPLETED NA 101 participants

Promotora Navigator - Culturally Appropriate Patient Navigator

Vanderbilt University Medical Center

NCT03557801

COMPLETED NA 101 participants

Exercise Intervention in Women With Metastatic Breast Cancer

Dana-Farber Cancer Institute

NCT00405782

COMPLETED Phase 1 101 participants

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

Pfizer

NCT01597193

COMPLETED Phase 2 100 participants

Study Assessing the Potential for Reduced Rates of Implant Failure Using Multi-Beam Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer Patients With Implant Reconstructions

Memorial Sloan Kettering Cancer Center

NCT02086578

COMPLETED 100 participants

An Examination of Predictors of Indicators of Response to Celecoxib in Women Who Have a Diagnosis of Early Breast Cancer

University of Kansas

NCT00291122

COMPLETED NA 100 participants

Pilot for The Breast Cancer Endocrine Therapy Adherence (BETA) Trial

Yale University

NCT02256670

COMPLETED Phase 1 100 participants

Intensity Modulated Radiotherapy for Breast Cancer

Washington University School of Medicine

NCT00594477

COMPLETED Phase 1 100 participants

Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers

NYU Langone Health

NCT02883985

COMPLETED NA 100 participants

Improving Adherence to Recommended Surveillance in Breast Cancer Survivors

Duke University

NCT02189278

COMPLETED NA 100 participants

Multi-Reader Multi-Case Controlled Clinical Trial to Assess the Fujifilm FFDM and DBT Reader Training Program

Fujifilm Medical Systems USA

NCT02685566

COMPLETED NA 98 participants

Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer

NCIC Clinical Trials Group

NCT00066586

COMPLETED 98 participants

Inflammation-Induced CNS Glutamate During Breast Cancer Treatment

Emory University

NCT02421978

COMPLETED NA 98 participants

Team Based Psychosocial Care to Promote, Maintain and Restore Wellness of Breast Cancer Patients

Mayo Clinic

NCT03770598

COMPLETED 98 participants

Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy

Mayo Clinic

NCT01777802

COMPLETED 96 participants

Magnetic Resonance Imaging in Patients With Breast Cancer

M.D. Anderson Cancer Center

NCT00610181

COMPLETED Phase 2 95 participants

S0102: Docetaxel, Vinorelbine, and Filgrastim in Treating Women With Stage IV Breast Cancer

SWOG Cancer Research Network

NCT00015938

COMPLETED Phase 1 95 participants

Safety and Efficacy Study of HER2/Neu (E75) Vaccine in Breast Cancer

COL George Peoples, MD, FACS

NCT00854789

COMPLETED Phase 1 92 participants

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Puma Biotechnology

NCT00706030

COMPLETED Phase 3 89 participants

Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery

M.D. Anderson Cancer Center

NCT00542542

COMPLETED Phase 2 89 participants

Adjuvant High-Dose, Sequential Chemotherapy in Treating Patients With Resected Breast Cancer

Yale University

NCT00002679

COMPLETED 89 participants

A Cost-Effective Handheld Breast Scanner for Use in Low Resource Environments: A Validation Study

University of Pennsylvania

NCT02814292

COMPLETED 85 participants

Physician-Patient Communication About Breast Cancer-Related Internet Information and Its Effect on Patient Satisfaction and Anxiety

Memorial Sloan Kettering Cancer Center

NCT00712569

COMPLETED NA 84 participants

A Web-Based Tool to Improve Breast Cancer Survivorship

Northwestern University

NCT03849573

COMPLETED Phase 1 84 participants

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

BBB-Therapeutics B.V.

NCT01386580

COMPLETED NA 84 participants

Acupuncture for Hot Flashes in Hormone Receptor-Positive Breast Cancer, a Randomized Controlled Trial

Dana-Farber Cancer Institute

NCT03783546

COMPLETED Phase 2 83 participants

Eribulin in HER2 Negative Metastatic BrCa

Dana-Farber Cancer Institute

NCT01827787

COMPLETED NA 82 participants

Cytokine Expression During Radiation for Breast Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00836186

COMPLETED Phase 2 82 participants

Carvedilol for the Prevention of Anthracycline/Anti-HER2 Therapy Associated Cardiotoxicity Among Women With HER2-Positive Breast Cancer Using Myocardial Strain Imaging for Early Risk Stratification

Memorial Sloan Kettering Cancer Center

NCT02177175

COMPLETED NA 81 participants

Enhancing Exercise in Breast Cancer Survivors

Duke University

NCT01849978

COMPLETED 81 participants

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

University of California, San Francisco

NCT00755313

COMPLETED NA 80 participants

Mobile Health App to Promote Participation of Black Women in Breast Cancer Clinical Trials

UNC Lineberger Comprehensive Cancer Center

NCT06361056

COMPLETED Phase 2 80 participants

Folate Receptor Alpha Peptide Vaccine With GM-CSF in Patients With Triple Negative Breast Cancer

Marker Therapeutics

NCT02593227

COMPLETED Phase 1 80 participants

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

National Cancer Institute (NCI)

NCT00001302

COMPLETED Phase 2 79 participants

Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer

SCRI Development Innovations

NCT00405938

COMPLETED NA 79 participants

Evaluating and Comparing Two Surgical Methods for Treatment of Early Stage Breast Cancer

Emory University

NCT01271738

COMPLETED NA 78 participants

Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program

Case Comprehensive Cancer Center

NCT04365569

COMPLETED Phase 2 77 participants

Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer

Eisai

NCT01439282

COMPLETED Phase 2 76 participants

Docetaxel With Bevacizumab as First-Line Therapy in Treating Women With Stage IV Breast Cancer

Translational Oncology Research International

NCT00217672

COMPLETED 76 participants

Contrast-Enhanced MRI for the Characterization of Ductal Carcinoma in Situ (DCIS)

University of California, San Francisco

NCT00804128

COMPLETED Phase 2 75 participants

Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer

University of Alabama at Birmingham

NCT00530868

COMPLETED Phase 1 75 participants

A Study of Giredestrant (GDC-9545) in Postmenopausal Women With Stage I-III Operable, Estrogen Receptor-Positive Breast Cancer

Genentech

NCT03916744

← Previous Page 19 of 26 Next →

Phase Distribution

PhaseTrial count
Phase 1 235
Phase 2 256
Phase 3 100
Phase 4 20

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Breast Cancer right now

423 recruiting of 1,251 indexed (34% open).

Phase mix: 120 late (III/IV) vs 491 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (98 trials), 9 others listed. 50 shown below, recruiting first. #1 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer?

PlainTrial tracks 1,251 US clinical trials for Breast Cancer, of which 423 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.