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NCT00019812 · ClinicalTrials.gov registry record · Phase 2
Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2
A Phase 2 study of Breast Cancer, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- Phase 2
- Development phase
- 55
- Enrollment target
- 3
- Study locations
NCT00019812 is a Phase 2 study of Breast Cancer that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 55 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 3 study locations across 3 states.
The verdict
NCT00019812, a Phase 2 study of Breast Cancer, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 55 participants
- Enrollment target
- 3
- Study locations
Study Summary
RATIONALE: Monoclonal antibodies such as trastuzumab can locate tumor cells and deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to make tumor cells stop dividing so they stop growing or die. Combining monoclonal antibody therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of trastuzumab plus paclitaxel in treating patients who have metastatic breast cancer that overexpresses HER2.
Conditions Studied
Interventions
- DRUG paclitaxel
- BIOLOGICAL trastuzumab
Study Locations (3)
Florida
- Holy Cross Hospital - Fort Lauderdale
Maryland
- Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support - Bethesda
West Virginia
- Mary Babb Randolph Center - Morgantown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 1999-08 |
| Est. Completion | 2004-02 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00019812
The ClinicalTrials.gov registry entry for NCT00019812 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The listed sponsor is National Institutes of Health Clinical Center (CC), which has 338 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which paclitaxel is the first listed.
NCT00019812 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Florida, Maryland, West Virginia.
Frequently Asked Questions
What is clinical trial NCT00019812 about?
NCT00019812 is a clinical study titled "Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2". RATIONALE: Monoclonal antibodies such as trastuzumab can locate tumor cells and deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to make tumor cells stop dividing so they stop growing or die. Combining monoclonal antibody therapy wi...
What is the current status of trial NCT00019812?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 1999-08. Estimated completion is 2004-02.
What conditions does trial NCT00019812 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00019812?
The interventions under investigation include: paclitaxel (DRUG), trastuzumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT00019812?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00019812 being conducted?
This trial has 3 study locations across Florida, Maryland, West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.