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Bladder Cancer clinical trials
74 of 179 indexed Bladder Cancer trials are currently recruiting.
179 US clinical trials · 74 currently recruiting
Bladder Cancer is the subject of 179 registered US clinical trials on ClinicalTrials.gov, 74 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 84 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 17 of these trials.
The research picture
Bladder Cancer has 179 registered US clinical trials, 74 of them open to new participants right now, about 41% of the total.
- 74
- recruiting participants now
- 41%
- of trials open to enrollment
- 14
- in Phase 3–4 (later-stage)
- 17
- top sponsor: Memorial Sloan Kettering Cancer Center
Active & Recent Trials
179 total, page 3 of 4
3 Tesla MRI in Patients With Bladder Cancer
University of Cincinnati
NCT00938145
Evaluating Bladder CARE™, a New Non-Invasive Urine Test, for Bladder Cancer Detection in Inconclusive Cases
Pangea Laboratory
NCT06870253
A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors
Memorial Sloan Kettering Cancer Center
NCT03693014
A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer
Memorial Sloan Kettering Cancer Center
NCT02989584
A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy
Memorial Sloan Kettering Cancer Center
NCT03520491
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors
Carisma Therapeutics
NCT04660929
Study of CAbozantinib in Combination with AtezolizumaB for Muscle-Invasive BladdEr Cancer
Deepak Kilari
NCT04289779
Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant
M.D. Anderson Cancer Center
NCT00082706
Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]
Memorial Sloan Kettering Cancer Center
NCT03504163
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
Arcus Biosciences
NCT05891171
Integrated Actionable Aging Assessment for Cancer Patients Pilot
University of Colorado, Denver
NCT05871008
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium
M.D. Anderson Cancer Center
NCT00756639
Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04386746
(CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer
Weill Medical College of Cornell University
NCT03837821
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer
UNC Lineberger Comprehensive Cancer Center
NCT03978624
A Study of Oral Erdafitinib in People With Recurrent Non-Invasive Bladder Cancer
Memorial Sloan Kettering Cancer Center
NCT04917809
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
Brigham and Women's Hospital
NCT04018053
Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT02845323
Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients
University of Kansas Medical Center
NCT04046094
A Phase II Multicenter Study of Chemotherapy Versus Chemotherapy Plus Durvalumab (MEDI 4736) in Patients With Lymph Node Positive Urothelial Carcinoma of the Bladder
M.D. Anderson Cancer Center
NCT05137262
A Window of Opportunity Phase I Study of UGN-201 in Patients With Bladder Cancer Undergoing Radical Cystectomy Protocol #: 2021-0630
M.D. Anderson Cancer Center
NCT05055050
Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment
AstraZeneca
NCT02695121
The New England Bladder Cancer Study
National Cancer Institute (NCI)
NCT00342875
Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-612)
Spectrum Pharmaceuticals
NCT00598806
The Efficacy of the Bladder EpiCheck for Detection of Recurrent Urothelial Cell Carcinoma
Nucleix
NCT02700464
Survivin Urine mRNA Assay Risk of Bladder Cancer Study
Fujirebio Diagnostics
NCT00315653
Bladder Cancer Case Control Study of Arsenic in Water
National Institute of Environmental Health Sciences (NIEHS)
NCT00011518
A Comparison of the Studer Pouch Versus the T-Pouch Orthotopic Neobladder Urinary Diversion in Bladder Cancer Patients
University of Southern California
NCT01008865
Eflornithine in Treating Patients With Bladder Cancer
National Cancer Institute (NCI)
NCT00003814
A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 2)
Hoffmann-La Roche
NCT02108652
UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearch
Matthew Milowsky, MD
NCT02643043
Screening for Bladder Cancer
Baylor College of Medicine
NCT00848627
Fiber-Optic Confocal Microscopy of the Urinary Tract Histopathology
Stanford University
NCT00801762
Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors
Dan Zandberg
NCT04157985
Health-Related Quality of Life in Patients With Bladder Cancer
David Latini
NCT00744744
Vicinium Treatment for Subjects With Non-muscle Invasive Bladder Cancer Previously Treated With BCG
Sesen Bio
NCT02449239
A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1)
Hoffmann-La Roche
NCT02951767
Genetic Susceptibility to Tumor Recurrence and Progression in Patients With Non-Muscle Invasive Bladder Cancer
Memorial Sloan Kettering Cancer Center
NCT00582387
A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer
Bristol-Myers Squibb
NCT04209114
Docetaxel in Treating Patients With Solid Tumors
Alliance for Clinical Trials in Oncology
NCT00003565
PlasmaKinetic (PK) Button Vaporization Electrode for Treatment of Bladder Tumors
Emory University
NCT01567462
Intravesical AD 32 (Valrubicin) in Patients With Carcinoma in Situ (CIS) of the Bladder Who Have Failed or Have Recurrence Following Treatment With Bacillus Calmette-guerin (BCG)
Endo Pharmaceuticals
NCT01316874
Relationship Between Tumor Mutation Burden and Predicted Neo-antigen Burden in Patients With Advanced Melanoma or Bladder Cancer Treated With Nivolumab or Nivolumab Plus Ipilimumab (CA209-260)
Memorial Sloan Kettering Cancer Center
NCT02553642
Using PROMIS as Part of Routine Clinical Care for Racially Diverse Prostate and Bladder Cancer Patients
UNC Lineberger Comprehensive Cancer Center
NCT03156244
A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma
Ikena Oncology
NCT04200963
Chemotherapy in Treating Patients With Early-Stage Bladder Cancer
Eastern Cooperative Oncology Group
NCT00003129
Resiliency in Patients Undergoing Radical Cystectomy for Bladder Cancer
University of Kansas Medical Center
NCT06337305
Physical Therapy in Pre-cystectomy Patients
UNC Lineberger Comprehensive Cancer Center
NCT05978570
FITBIT Study on Mobility and Readmissions After Radical Cystectomy
University of Pennsylvania
NCT04314778
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors
Incyte Corporation
NCT04580485
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 39 |
| Phase 2 | 45 |
| Phase 3 | 14 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Bladder Cancer Trial Landscape
179 indexed Bladder Cancer studies · 74 recruiting (41%).
Phase mix: 14 late (III/IV) vs 84 early (I/II).
Top sponsor: Memorial Sloan Kettering Cancer Center (17 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Bladder Cancer?
PlainTrial tracks 179 US clinical trials for Bladder Cancer, of which 74 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Bladder Cancer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.