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ClinicalTrials.gov 74 recruiting now official registry

Bladder Cancer clinical trials

74 of 179 indexed Bladder Cancer trials are currently recruiting.

179 US clinical trials · 74 currently recruiting

Bladder Cancer is the subject of 179 registered US clinical trials on ClinicalTrials.gov, 74 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 84 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 17 of these trials.

The research picture

Bladder Cancer has 179 registered US clinical trials, 74 of them open to new participants right now, about 41% of the total.

74
recruiting participants now
41%
of trials open to enrollment
14
in Phase 3–4 (later-stage)
17
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 139Phase 245Phase 314

Active & Recent Trials

179 total, page 4 of 4

COMPLETED Phase 2 51 participants

Neoadjuvant Dose Dense Gemcitabine and Cisplatin (DD GC) In Patients With Muscle-Invasive Bladder Cancer

Memorial Sloan Kettering Cancer Center

NCT01589094

COMPLETED Phase 1 48 participants

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Arcus Biosciences

NCT03629756

COMPLETED Phase 1 48 participants

A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)

Celldex Therapeutics

NCT00709462

COMPLETED Phase 2 46 participants

Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium

Eastern Cooperative Oncology Group

NCT00053209

COMPLETED Phase 2 39 participants

Dose-Dense MVAC With Pegfilgrastim Support in Subjects With Muscle-Invasive Urothelial Carcinoma

Dana-Farber Cancer Institute

NCT00808639

COMPLETED Phase 2 34 participants

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Bristol-Myers Squibb

NCT00389155

COMPLETED Phase 2 31 participants

S0031, ZD 1839 in Treating Patients With Advanced Cancer of the Urinary Tract

SWOG Cancer Research Network

NCT00014144

COMPLETED Phase 2 30 participants

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03914794

COMPLETED Phase 2 30 participants

Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer

Memorial Sloan Kettering Cancer Center

NCT00002919

COMPLETED 28 participants

Quality of Life and Symptom Management in Patients With Bladder Cancer

David Latini

NCT00772018

COMPLETED Phase 1 27 participants

Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder Cancer

Halozyme Therapeutics

NCT00318643

COMPLETED Phase 2 27 participants

Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer

UNC Lineberger Comprehensive Cancer Center

NCT00380029

COMPLETED 26 participants

Feasibility Evaluation of Magnetic Resonance Imaging and Positron Emission Tomography for Bladder Cancer Diagnosis and Staging

Memorial Sloan Kettering Cancer Center

NCT00612326

COMPLETED Phase 1 22 participants

Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer

Baylor College of Medicine

NCT02885974

COMPLETED NA 19 participants

Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers

Dartmouth-Hitchcock Medical Center

NCT02648178

COMPLETED Phase 1 18 participants

A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors

Poniard Pharmaceuticals

NCT00465725

COMPLETED Phase 1 18 participants

Avelumab Plus Bacille Calmette-Guerin (BCG) in Patients With Non-muscle Invasive Bladder Cancer

University of Oklahoma

NCT03892642

COMPLETED Phase 2 17 participants

Oral Lenalidomide and Intravesical BCG for Therapy of Bladder Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT01373294

COMPLETED 16 participants

The Impact of Preoperative Urostomy Education on Patients and Families

University of Kansas Medical Center

NCT04334226

COMPLETED Phase 1 15 participants

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Lipac Oncology

NCT03081858

COMPLETED NA 10 participants

Near Infrared Fluorescence Imaging for Bladder Cancer Detection

Edward Messing

NCT03058705

COMPLETED NA 8 participants

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients

University of Utah

NCT06002269

COMPLETED Phase 2 8 participants

Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

National Cancer Institute (NCI)

NCT02788201

COMPLETED Phase 3 8 participants

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

UroGen Pharma

NCT05136898

COMPLETED Phase 1 6 participants

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Nagla Abdel Karim

NCT03023319

COMPLETED Phase 2 5 participants

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Seagen

NCT03245736

COMPLETED Phase 2

Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer

Eastern Cooperative Oncology Group

NCT00004223

COMPLETED Phase 2

AD 32 With or Without BCG After Surgery in Treating Patients With Newly Diagnosed or Recurrent Superficial Bladder Cancer

Anthra Pharmaceuticals

NCT00003759

COMPLETED Phase 2

R115777 in Treating Patients With Advanced Bladder Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT00006376

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Phase Distribution

PhaseTrial count
Phase 1 39
Phase 2 45
Phase 3 14

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Bladder Cancer Trial Landscape

179 indexed Bladder Cancer studies · 74 recruiting (41%).

Phase mix: 14 late (III/IV) vs 84 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (17 trials), 9 others listed. 29 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Bladder Cancer?

PlainTrial tracks 179 US clinical trials for Bladder Cancer, of which 74 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Bladder Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.