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ClinicalTrials.gov 74 recruiting now early-phase tilt #61 of 28,707 conditions

Bladder Cancer: early-phase trial registry

74 of 179 indexed Bladder Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #61 of 28,707 conditions by registered trial count.

179 US clinical trials · 74 currently recruiting · #61 of 28,707 conditions by registered trial count

Bladder Cancer: 179 US clinical trials tracked, 74 recruiting.

Bladder Cancer is the subject of 179 registered US clinical trials on ClinicalTrials.gov, 74 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 84 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 17 of these trials.

Enrollment posture brief

Registry condition bladder-cancer

OPEN 74 | RECR 41% | LATE 14 | EARLY 84 | RANK #61 | SPON 17

Nearest open-share peer: Pediatric Obesity (41% recruiting · 46 trials)

Alcohol Use Disorder58.9%Endometrial Cancer57.4%Malignant Solid Neoplasm53.1%Traumatic Brain Injury43.6%Bladder Cancer (this)41%
Open-enrollment share among volume-matched conditions near Bladder Cancer

Bladder Cancer lists 74 open slots (41% of 179 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Bladder Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Bladder Cancer is recruiting above its size-band peers.

    74 of 179 indexed trials (41.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Bladder Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 17 of 179 trials (9.5%). 92 distinct sponsors appear on at least one study for this condition label.

  3. Typical Bladder Cancer enrolment sits around 98 participants.

    Median target enrolment is 98 among the 176 trials that report a genuine target (sentinel values excluded). 90 of those (51.1%) plan for fewer than 100 participants.

  4. Bladder Cancer research is mostly interventional.

    131 interventional and 48 observational studies make up this index (73.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 139Phase 245Phase 314

Open and recent trials

179 total, page 4 of 4

COMPLETED Phase 2 51 participants

Neoadjuvant Dose Dense Gemcitabine and Cisplatin (DD GC) In Patients With Muscle-Invasive Bladder Cancer

Memorial Sloan Kettering Cancer Center

NCT01589094

COMPLETED Phase 1 48 participants

A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Arcus Biosciences

NCT03629756

COMPLETED Phase 1 48 participants

A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)

Celldex Therapeutics

NCT00709462

COMPLETED Phase 2 46 participants

Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium

Eastern Cooperative Oncology Group

NCT00053209

COMPLETED Phase 2 39 participants

Dose-Dense MVAC With Pegfilgrastim Support in Subjects With Muscle-Invasive Urothelial Carcinoma

Dana-Farber Cancer Institute

NCT00808639

COMPLETED Phase 2 34 participants

First-Line Treatment of Advanced Bladder Cancer Randomized vs. Gemcitabine ± Vinflunine in Patients Ineligible to Receive Cisplatin-Based Therapy

Bristol-Myers Squibb

NCT00389155

COMPLETED Phase 2 31 participants

S0031, ZD 1839 in Treating Patients With Advanced Cancer of the Urinary Tract

SWOG Cancer Research Network

NCT00014144

COMPLETED Phase 2 30 participants

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03914794

COMPLETED Phase 2 30 participants

Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer

Memorial Sloan Kettering Cancer Center

NCT00002919

COMPLETED 28 participants

Quality of Life and Symptom Management in Patients With Bladder Cancer

David Latini

NCT00772018

COMPLETED Phase 1 27 participants

Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder Cancer

Halozyme Therapeutics

NCT00318643

COMPLETED Phase 2 27 participants

Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer

UNC Lineberger Comprehensive Cancer Center

NCT00380029

COMPLETED 26 participants

Feasibility Evaluation of Magnetic Resonance Imaging and Positron Emission Tomography for Bladder Cancer Diagnosis and Staging

Memorial Sloan Kettering Cancer Center

NCT00612326

COMPLETED Phase 1 22 participants

Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer

Baylor College of Medicine

NCT02885974

COMPLETED NA 19 participants

Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers

Dartmouth-Hitchcock Medical Center

NCT02648178

COMPLETED Phase 1 18 participants

A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors

Poniard Pharmaceuticals

NCT00465725

COMPLETED Phase 1 18 participants

Avelumab Plus Bacille Calmette-Guerin (BCG) in Patients With Non-muscle Invasive Bladder Cancer

University of Oklahoma

NCT03892642

COMPLETED Phase 2 17 participants

Oral Lenalidomide and Intravesical BCG for Therapy of Bladder Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT01373294

COMPLETED 16 participants

The Impact of Preoperative Urostomy Education on Patients and Families

University of Kansas Medical Center

NCT04334226

COMPLETED Phase 1 15 participants

Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer

Lipac Oncology

NCT03081858

COMPLETED NA 10 participants

Near Infrared Fluorescence Imaging for Bladder Cancer Detection

Edward Messing

NCT03058705

COMPLETED NA 8 participants

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients

University of Utah

NCT06002269

COMPLETED Phase 2 8 participants

Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

National Cancer Institute (NCI)

NCT02788201

COMPLETED Phase 3 8 participants

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

UroGen Pharma

NCT05136898

COMPLETED Phase 1 6 participants

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Nagla Abdel Karim

NCT03023319

COMPLETED Phase 2 5 participants

Tisotumab Vedotin Continued Treatment in Patients With Solid Tumors.

Seagen

NCT03245736

COMPLETED Phase 2

Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer

Eastern Cooperative Oncology Group

NCT00004223

COMPLETED Phase 2

AD 32 With or Without BCG After Surgery in Treating Patients With Newly Diagnosed or Recurrent Superficial Bladder Cancer

Anthra Pharmaceuticals

NCT00003759

COMPLETED Phase 2

R115777 in Treating Patients With Advanced Bladder Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT00006376

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Phase Distribution

PhaseTrial count
Phase 1 39
Phase 2 45
Phase 3 14

Named interventions

Most-linked intervention names on Bladder Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
10 trials
Cisplatin Drug
7 trials
Atezolizumab Drug
5 trials
Pembrolizumab Drug
5 trials
Pembrolizumab Biological
4 trials
Nivolumab Drug
3 trials
Leucovorin Drug
3 trials
Docetaxel Drug
3 trials

US sites by state

Facility locations filed on Bladder Cancer trials. A trial with sites in several states counts in each.

California 58 trials
New York 52 trials
Texas 48 trials
Maryland 35 trials
Florida 34 trials
Pennsylvania 29 trials
Illinois 25 trials
North Carolina 23 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Bladder Cancer page

179 registered trials, 74 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Bladder Cancer condition card totals 179 registered trials; most-linked intervention Gemcitabine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.