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COMPLETED NA

UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearch

NCT02643043 · View on ClinicalTrials.gov ↗

Study Summary

This comprehensive genomic analysis and biospecimen repository study incorporates Next Generation Sequencing (NGS) of archival tumor tissue from 200 subjects with metastatic urothelial cancer in support of several parallel goals. The immediate goal involves generation of a comprehensive report identifying subject specific genetic mutations and/or alterations based on NGS. Additionally, DNA and RNA extracted from tumor specimens and any remaining blocks/slides from the NGS will be stored for future research. Long-term, the goal of this endeavor is to support collaborative translational research projects in metastatic urothelial cancer by allowing investigators to interrogate abstracted coded clinical data linked to data from any biospecimen studies.

Interventions

  • OTHER Biospecimen Collection

Study Locations (8)

New York

  • Ichan School of Medicine at Mount Sinai — New York
  • Memorial Sloan Kettering Cancer Center — New York

California

  • University of Southern Cailfornia — Los Angeles

Illinois

  • University of Chicago Medical Center — Chicago

Maryland

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center — Baltimore

North Carolina

  • University of North Carolina - Lineberger Comprehensive Cancer Center — Chapel Hill

Pennsylvania

  • Fox Chase Cancer Center — Philadelphia

Washington

  • University of Washignton/Fred Hutchinson Cancer Research Center — Seattle

Trial Details

FieldValue
Enrollment Target 219 participants
Start Date 2017-07-26
Est. Completion 2023-09-13
Phase NA

Sponsor

Matthew Milowsky, MD

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02643043

The ClinicalTrials.gov registry entry for NCT02643043 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 219 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Matthew Milowsky, MD, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Bladder Cancer appearing as the primary indexed condition, and to 1 intervention — of which Biospecimen Collection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02643043 reports 8 study locations spanning 7 distinct geographic areas — top geographies include New York, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02643043 about?

NCT02643043 is a clinical study titled "UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearch". This comprehensive genomic analysis and biospecimen repository study incorporates Next Generation Sequencing (NGS) of archival tumor tissue from 200 subjects with metastatic urothelial cancer in support of several parallel goals. The immediate goal involves generation of a comprehensive report ident...

What is the current status of trial NCT02643043?

This trial is currently completed. It is a NA study. The enrollment target is 219 participants. The study started on 2017-07-26. Estimated completion is 2023-09-13.

What conditions does trial NCT02643043 study?

This clinical trial studies the following conditions: Bladder Cancer, Urothelial Carcinoma, Urethral Cancer, Cancer of the Ureter. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02643043?

The interventions under investigation include: Biospecimen Collection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02643043?

This trial is sponsored by Matthew Milowsky, MD, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02643043 being conducted?

This trial has 8 study locations across California, Illinois, Maryland, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial