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Asthma: full-pipeline trial registry
70 of 378 indexed Asthma trials are currently recruiting.
Corpus placement: #15 of 28,707 conditions by registered trial count.
378 US clinical trials · 70 currently recruiting · #15 of 28,707 conditions by registered trial count
Asthma: 378 US clinical trials tracked, 70 recruiting.
Asthma is the subject of 378 registered US clinical trials on ClinicalTrials.gov, 70 of them currently open to new participants. 89 are in Phase 3-4 (later-stage) and 108 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 24 of these trials.
Enrollment posture brief
Registry condition asthma
OPEN 70 | RECR 19% | LATE 89 | EARLY 108 | RANK #15 | SPON 24
Volume-matched condition peers
Nearest open-share peer: Relapsing Remitting Multiple Sclerosis (19% recruiting · 27 trials)
Asthma lists 70 open slots (19% of 378 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Asthma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Asthma is recruiting below its size-band peers.
70 of 378 indexed trials (18.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Asthma trials is spread across many organizations.
GlaxoSmithKline accounts for 24 of 378 trials (6.3%). 161 distinct sponsors appear on at least one study for this condition label.
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Typical Asthma enrolment sits around 144 participants.
Median target enrolment is 144 among the 375 trials that report a genuine target (sentinel values excluded). 160 of those (42.7%) plan for fewer than 100 participants.
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Asthma research is mostly interventional.
298 interventional and 80 observational studies make up this index (78.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
378 total, page 1 of 8
Personalized Environment and Genes Study
National Institute of Environmental Health Sciences (NIEHS)
NCT00341237
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Sanguine Biosciences
NCT05635266
GRANITE: Airsupra Effectiveness in the Real World
AstraZeneca
NCT07141277
Role of Genetic Factors in the Development of Lung Disease
National Heart, Lung, and Blood Institute (NHLBI)
NCT00001532
Individualizing Treatment for Asthma in Primary Care (Full Study)
DARTNet Institute
NCT07052942
Home Hospital for Suddenly Ill Adults
Brigham and Women's Hospital
NCT03524222
Reducing Overuse of Antibiotics With Decision Support
Vanderbilt University Medical Center
NCT06788093
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
Teva Branded Pharmaceutical Products R&D
NCT06052267
Registry of Asthma Characterization and Recruitment 3 (RACR3)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT05272241
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
Sanofi
NCT05097287
Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma
Sanofi
NCT06676319
Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma.
Sanofi
NCT06609239
Acoustic Waveform Respiratory Evaluation
Indiana University
NCT06512064
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
National Institute of Environmental Health Sciences (NIEHS)
NCT01143480
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
Teva Branded Pharmaceutical Products R&D
NCT06664619
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
AstraZeneca
NCT06932263
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Eli Lilly and Company
NCT07219173
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
AstraZeneca
NCT06307665
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
National Institute of Environmental Health Sciences (NIEHS)
NCT02327897
BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma
Columbia University
NCT05341726
Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care
Kavita Parikh
NCT05991115
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Benjamin Medoff
NCT00595491
Protocol CAUSE-03 / CHEETAH
National Institute of Allergy and Infectious Diseases (NIAID)
NCT06136091
Patient Reported Outcomes for Acute Asthma Care Treatment
Stanford University
NCT04349020
Asthma Symptom Perception Study
Icahn School of Medicine at Mount Sinai
NCT06612294
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
GlaxoSmithKline
NCT05757102
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Mario Castro, MD, MPH
NCT04624490
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Pfizer
NCT06977581
Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma
Regeneron Pharmaceuticals
NCT06572228
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
AstraZeneca
NCT06023589
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
Oregon Health and Science University
NCT06106646
ASTHMAXcel Voice Study
Montefiore Medical Center
NCT06935084
A Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma (DOMINICA)
AstraZeneca
NCT05692180
Asthma and Technology in Emerging African American Adults
University of Michigan
NCT05445583
AeviceMD for Detection of Wheeze in Pediatric and Adult Populations
Aevice Health Pte.
NCT06691971
Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects
Biometry
NCT07228026
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
GlaxoSmithKline
NCT06979323
Inhaler Trainer Efficacy Study
Koronis Biomedical Technologies
NCT06461403
A Study to Evaluate Solriktug in Adult Participants With Asthma
Uniquity One (UNI)
NCT06496607
A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma
Amgen
NCT06637371
Escitalopram in Asthma Patients With Frequent Exacerbation
University of Texas Southwestern Medical Center
NCT06216535
Innate Immunity in Allergic Asthma
University of Central Florida
NCT06068335
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
Johns Hopkins University
NCT06273072
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
Vanderbilt University Medical Center
NCT05254314
Comparison of Microglial Activation in Severe Asthma and Healthy Controls
University of Wisconsin, Madison
NCT06299592
Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)
Sanofi
NCT06191315
Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
University of California, San Francisco
NCT05757583
Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation
University of Colorado, Denver
NCT05259904
Viral Mucosal Reprogramming
The University of Texas Medical Branch, Galveston
NCT05331170
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
Gelb, Arthur F., M.D.
NCT00576069
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 27 |
| Phase 2 | 81 |
| Phase 3 | 51 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Asthma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Asthma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Asthma page
378 registered trials, 70 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 70 Asthma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- GlaxoSmithKline sponsors the most Asthma trials on record, review their full trial history before evaluating a specific study. See GlaxoSmithKline's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Asthma condition card totals 378 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.