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NCT04624490 · ClinicalTrials.gov registry record · Phase 1
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
A Phase 1 study of Asthma and Cystic Fibrosis, sponsored by Mario Castro, MD, MPH.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 260
- Enrollment target
- 1
- Study location
NCT04624490: Recruiting Phase 1 study of Asthma and Cystic Fibrosis, sponsored by Mario Castro, MD, MPH.
NCT04624490 is a Phase 1 study of Asthma and Cystic Fibrosis that is actively recruiting participants, run by Mario Castro, MD, MPH. The registered enrollment target is 260 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04624490, a Phase 1 study of Asthma and Cystic Fibrosis, is actively recruiting participants, sponsored by Mario Castro, MD, MPH.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 260 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
Primary Outcome
Ratio of xenon signal dissolved in RBCs to xenon signal dissolved in Barrier Tissues
Conditions Studied
Interventions
- DRUG Hyperpolarized Xe129
Study Locations (1)
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2020-11-02 |
| Est. Completion | 2026-10-26 |
| Phase | Phase 1 |
What NCT04624490 shows while recruiting
NCT04624490 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (83% lower).
The record links to 7 conditions, with Asthma appearing as the primary indexed condition, and to 1 intervention - of which Hyperpolarized Xe129 is the first listed.
NCT04624490 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT04624490 about?
NCT04624490 is a clinical study titled "Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease". The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
What is the current status of trial NCT04624490?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 260 participants. The study started on 2020-11-02. Estimated completion is 2026-10-26.
What conditions does trial NCT04624490 study?
This clinical trial studies the following conditions: Asthma, Cystic Fibrosis, COPD, Pulmonary Hypertension, Interstitial Lung Disease.
What interventions are being tested in trial NCT04624490?
The interventions under investigation include: Hyperpolarized Xe129 (DRUG).
Who is sponsoring clinical trial NCT04624490?
This trial is sponsored by Mario Castro, MD, MPH, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04624490 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04624490's enrollment target sits among peer trials
260 137th of 374 higher than 238 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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