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Relapsing Remitting Multiple Sclerosis clinical trials
5 of 27 indexed Relapsing Remitting Multiple Sclerosis trials are currently recruiting.
27 US clinical trials · 5 currently recruiting
Relapsing Remitting Multiple Sclerosis is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Biogen, running 3 of these trials.
The research picture
Relapsing Remitting Multiple Sclerosis has 27 registered US clinical trials, 5 of them open to new participants right now, about 19% of the total.
- 5
- recruiting participants now
- 19%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Biogen
Active & Recent Trials
27 total, page 1 of 1
Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis
Hoffmann-La Roche
NCT05949580
Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04047628
Functional Outcomes From Diets in Multiple Sclerosis
University of Alabama at Birmingham
NCT05327322
Exploratory Study on the Timing of Multiple Sclerosis (MS) Symptoms
University of Louisville
NCT00919217
The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
SetPoint Medical Corporation
NCT06796504
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)
Hoffmann-La Roche
NCT05123703
A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
Novartis Pharmaceuticals
NCT05090371
Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis
Terry L. Wahls
NCT04009005
Serum Neurofilament Light in Multiple Sclerosis
Dent Neuroscience Research Center
NCT06282081
Reduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab Treatment
University of Southern California
NCT05171972
WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis
Kessler Foundation
NCT05755061
Efficacy and Safety of Oral BG00012 in Relapsing-Remitting Multiple Sclerosis
Biogen
NCT00420212
Evaluation of Patient Retention of Fingolimod vs. Currently Approved Disease Modifying Therapy in Patients With Relapsing Remitting Multiple Sclerosis.
Novartis Pharmaceuticals
NCT01623596
A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2
Biogen
NCT03093324
Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis
Novartis Pharmaceuticals
NCT00879658
Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis
Contineum Therapeutics
NCT06083753
A Combination Trial of Copaxone Plus Estriol in Relapsing Remitting Multiple Sclerosis (RRMS)
University of California, Los Angeles
NCT00451204
A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
Novartis
NCT06395909
Development of a Motivational Intervention to Improve Treatment Adherence in MS
University of Missouri, Kansas City
NCT01925690
Safety Study of BIIB033 in Subjects With Multiple Sclerosis
Biogen
NCT01244139
Utilization of the Ketogenic Diet in Patient With Relapsing Remitting MS
University of Virginia
NCT03718247
Evaluating the Efficacy and Safety of Transitioning Patients From Natalizumab to Ocrelizumab
Providence Health & Services
NCT03157830
Retrospective Study to Determine Effect of Rebif and Tecfidera on Infections and Lymphocytes
EMD Serono Research & Development Institute
NCT03284970
Melatonin in Patients With Multiple Sclerosis (MS).
Providence Health & Services
NCT03498131
Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS)
OhioHealth
NCT02258217
Glatiramer Acetate for Multiple Sclerosis With Autoimmune Comorbidities
University of Southern California
NCT01456416
Vitamin D Pilot Study in Patients With Multiple Sclerosis
University of Wisconsin, Madison
NCT01257958
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 3 |
| Phase 3 | 4 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Relapsing Remitting Multiple Sclerosis Trial Landscape
27 indexed Relapsing Remitting Multiple Sclerosis studies · 5 recruiting (19%).
Phase mix: 6 late (III/IV) vs 7 early (I/II).
Top sponsor: Biogen (3 trials), 9 others listed. 27 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Relapsing Remitting Multiple Sclerosis?
PlainTrial tracks 27 US clinical trials for Relapsing Remitting Multiple Sclerosis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Relapsing Remitting Multiple Sclerosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.