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ClinicalTrials.gov 5 recruiting now full pipeline

Relapsing Remitting Multiple Sclerosis: full-pipeline trial registry

5 of 27 indexed Relapsing Remitting Multiple Sclerosis trials are currently recruiting.

Corpus placement: #598 of 28,707 conditions by registered trial count.

27 US clinical trials · 5 currently recruiting · #598 of 28,707 conditions by registered trial count

Relapsing Remitting Multiple Sclerosis: 27 US clinical trials tracked, 5 recruiting.

Relapsing Remitting Multiple Sclerosis is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Biogen, running 3 of these trials.

Enrollment posture brief

Registry condition relapsing-remitting-multiple-sclerosis

OPEN 5 | RECR 19% | LATE 6 | EARLY 7 | RANK #598 | SPON 3

Nearest open-share peer: Asthma (19% recruiting · 378 trials)

Alopecia Areata55.6%Acute Ischemic Stroke44.4%Adenocarcinoma25.9%Acne22.2%Relapsing Remitting Mult (th…19%
Open-enrollment share among volume-matched conditions near Relapsing Remitting Multiple Sclerosis

Relapsing Remitting Multiple Sclerosis lists 5 open slots (19% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Relapsing Remitting Multiple Sclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Relapsing Remitting Multiple Sclerosis is recruiting below its size-band peers.

    5 of 27 indexed trials (18.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Relapsing Remitting Multiple Sclerosis trials is spread across many organizations.

    Biogen accounts for 3 of 27 trials (11.1%). 20 distinct sponsors appear on at least one study for this condition label.

  3. Typical Relapsing Remitting Multiple Sclerosis enrolment sits around 80 participants.

    Median target enrolment is 80 among the 26 trials that report a genuine target (sentinel values excluded). 14 of those (53.8%) plan for fewer than 100 participants.

  4. Relapsing Remitting Multiple Sclerosis splits between interventional and observational designs.

    18 interventional and 9 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 23Phase 34Phase 42

Open and recent trials

27 total, page 1 of 1

RECRUITING 500 participants

Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis

Hoffmann-La Roche

NCT05949580

RECRUITING Phase 3 156 participants

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04047628

RECRUITING NA 100 participants

Functional Outcomes From Diets in Multiple Sclerosis

University of Alabama at Birmingham

NCT05327322

RECRUITING 80 participants

Exploratory Study on the Timing of Multiple Sclerosis (MS) Symptoms

University of Louisville

NCT00919217

RECRUITING NA 60 participants

The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

SetPoint Medical Corporation

NCT06796504

ACTIVE NOT RECRUITING Phase 3 188 participants

A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison With Fingolimod in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis (RRMS)

Hoffmann-La Roche

NCT05123703

ACTIVE NOT RECRUITING Phase 4 136 participants

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Novartis Pharmaceuticals

NCT05090371

ACTIVE NOT RECRUITING NA 44 participants

Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis

Terry L. Wahls

NCT04009005

ACTIVE NOT RECRUITING 42 participants

Serum Neurofilament Light in Multiple Sclerosis

Dent Neuroscience Research Center

NCT06282081

ACTIVE NOT RECRUITING 40 participants

Reduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab Treatment

University of Southern California

NCT05171972

ACTIVE NOT RECRUITING Phase 1 31 participants

WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis

Kessler Foundation

NCT05755061

COMPLETED Phase 3 1,234 participants

Efficacy and Safety of Oral BG00012 in Relapsing-Remitting Multiple Sclerosis

Biogen

NCT00420212

COMPLETED Phase 4 881 participants

Evaluation of Patient Retention of Fingolimod vs. Currently Approved Disease Modifying Therapy in Patients With Relapsing Remitting Multiple Sclerosis.

Novartis Pharmaceuticals

NCT01623596

COMPLETED Phase 3 506 participants

A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2

Biogen

NCT03093324

COMPLETED Phase 2 297 participants

Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis

Novartis Pharmaceuticals

NCT00879658

COMPLETED Phase 2 182 participants

Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis

Contineum Therapeutics

NCT06083753

COMPLETED Phase 2 158 participants

A Combination Trial of Copaxone Plus Estriol in Relapsing Remitting Multiple Sclerosis (RRMS)

University of California, Los Angeles

NCT00451204

COMPLETED 113 participants

A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis

Novartis

NCT06395909

COMPLETED NA 80 participants

Development of a Motivational Intervention to Improve Treatment Adherence in MS

University of Missouri, Kansas City

NCT01925690

COMPLETED Phase 1 47 participants

Safety Study of BIIB033 in Subjects With Multiple Sclerosis

Biogen

NCT01244139

COMPLETED 45 participants

Utilization of the Ketogenic Diet in Patient With Relapsing Remitting MS

University of Virginia

NCT03718247

COMPLETED 43 participants

Evaluating the Efficacy and Safety of Transitioning Patients From Natalizumab to Ocrelizumab

Providence Health & Services

NCT03157830

COMPLETED 34 participants

Retrospective Study to Determine Effect of Rebif and Tecfidera on Infections and Lymphocytes

EMD Serono Research & Development Institute

NCT03284970

COMPLETED Early Phase 1 30 participants

Melatonin in Patients With Multiple Sclerosis (MS).

Providence Health & Services

NCT03498131

COMPLETED NA 30 participants

Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS)

OhioHealth

NCT02258217

COMPLETED 10 participants

Glatiramer Acetate for Multiple Sclerosis With Autoimmune Comorbidities

University of Southern California

NCT01456416

COMPLETED Phase 1

Vitamin D Pilot Study in Patients With Multiple Sclerosis

University of Wisconsin, Madison

NCT01257958

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 3
Phase 3 4
Phase 4 2

Named interventions

Most-linked intervention names on Relapsing Remitting Multiple Sclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Ofatumumab Drug
2 trials
Fingolimod Drug
2 trials
Disease Modifying therapy Drug
1 trials
Modified Atkins diet Other
1 trials
PIPE-307 Dose B Drug
1 trials
PIPE-307 Dose A Drug
1 trials
19 nor vitamin d Drug
1 trials

US sites by state

Facility locations filed on Relapsing Remitting Multiple Sclerosis trials. A trial with sites in several states counts in each.

California 11 trials
New Jersey 8 trials
Colorado 8 trials
Missouri 6 trials
Massachusetts 6 trials
Florida 6 trials
Arizona 6 trials
Washington 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Relapsing Remitting Multiple Sclerosis page

27 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Relapsing Remitting Multiple Sclerosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Biogen sponsors the most Relapsing Remitting Multiple Sclerosis trials on record, review their full trial history before evaluating a specific study. See Biogen's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Relapsing Remitting Multiple Sclerosis condition card totals 27 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.