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NCT05331170 · ClinicalTrials.gov registry record · Phase 2
Viral Mucosal Reprogramming
A Phase 2 study of Healthy and Asthma, sponsored by The University of Texas Medical Branch, Galveston.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT05331170: Recruiting Phase 2 study of Healthy and Asthma, sponsored by The University of Texas Medical Branch, Galveston.
NCT05331170 is a Phase 2 study of Healthy and Asthma that is actively recruiting participants, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 75 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05331170, a Phase 2 study of Healthy and Asthma, is actively recruiting participants, sponsored by The University of Texas Medical Branch, Galveston.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (AA) with cat dander allergy. Three groups (HC, AR, and AA) will undergo screening to establish clinical history, will undergo pulmonary function testing (spirometry), and will have blood drawn for clinical characterization (IgE, , ImmunoCAP, CBC and differential), and for assessing the presence of existing neutralizing antibody against RV16. Only those who meet criteria will be permitted to continue into the interventional and run-out phases of the study.
Primary Outcome
Q-PCR
Conditions Studied
Interventions
- BIOLOGICAL Research Grade RG-RV
Study Locations (1)
Texas
- University of Texas Medical Branch - Galveston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2023-04-27 |
| Est. Completion | 2027-05-01 |
| Phase | Phase 2 |
What NCT05331170 shows while recruiting
NCT05331170 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower).
The record links to 4 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Research Grade RG-RV is the first listed.
NCT05331170 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05331170 about?
NCT05331170 is a clinical study titled "Viral Mucosal Reprogramming". This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (A...
What is the current status of trial NCT05331170?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2023-04-27. Estimated completion is 2027-05-01.
What conditions does trial NCT05331170 study?
This clinical trial studies the following conditions: Healthy, Asthma, Allergic Rhinitis, Cat Allergy.
What interventions are being tested in trial NCT05331170?
The interventions under investigation include: Research Grade RG-RV (BIOLOGICAL).
Who is sponsoring clinical trial NCT05331170?
This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05331170 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05331170's enrollment target sits among peer trials
75 300th of 1090 higher than 781 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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