Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Use Disorder: early-phase trial registry
109 of 185 indexed Alcohol Use Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #60 of 28,707 conditions by registered trial count.
185 US clinical trials · 109 currently recruiting · #60 of 28,707 conditions by registered trial count
Alcohol Use Disorder: 185 US clinical trials tracked, 109 recruiting.
Alcohol Use Disorder is the subject of 185 registered US clinical trials on ClinicalTrials.gov, 109 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 75 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 13 of these trials.
Enrollment posture brief
Registry condition alcohol-use-disorder
OPEN 109 | RECR 59% | LATE 8 | EARLY 75 | RANK #60 | SPON 13
Volume-matched condition peers
Nearest open-share peer: Breast Carcinoma (59% recruiting · 107 trials)
Alcohol Use Disorder lists 109 open slots (59% of 185 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcohol Use Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcohol Use Disorder is recruiting above its size-band peers.
109 of 185 indexed trials (58.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Alcohol Use Disorder trials is spread across many organizations.
Yale University accounts for 13 of 185 trials (7%). 91 distinct sponsors appear on at least one study for this condition label.
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Typical Alcohol Use Disorder enrolment sits around 90 participants.
Median target enrolment is 90 among the 185 trials that report a genuine target (sentinel values excluded). 99 of those (53.5%) plan for fewer than 100 participants.
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Alcohol Use Disorder research is mostly interventional.
173 interventional and 12 observational studies make up this index (93.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
185 total, page 3 of 4
Piloting a Deaf Accessible Pre-Treatment for AUD
University of Massachusetts, Worcester
NCT07269119
Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder
University of California, San Francisco
NCT06518785
Enhancing Prospective Thinking in Early Recovery (BEAM)
Indiana University
NCT06283472
Ketone Ester Intervention in Alcohol Use Disorder
University of Pennsylvania
NCT04616781
Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection
Rush University Medical Center
NCT06139224
Spironolactone in Alcohol Use Disorder (SAUD)
National Institute on Drug Abuse (NIDA)
NCT05807139
MDMA for AUD/PTSD Comorbidity
Carolina L Haass-Koffler
NCT05943665
The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration
University of Rochester
NCT06319872
Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study
Wake Forest University Health Sciences
NCT06770556
Behavioral Alcohol Responses (BAR) Study
Carnegie Mellon University
NCT03467191
Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse
Virginia Polytechnic Institute and State University
NCT04788004
TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study
University of New Mexi
NCT06074341
Clinical Course of Alcohol Use Disorder Recovery
University of South Florida
NCT05607290
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Boston University Charles River Campus
NCT04771650
Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 1
Mikhail N Koffarnus
NCT03883126
Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder
Imbrium Therapeutics
NCT06545916
Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use
University of California, San Francisco
NCT05191446
Black Church Treatment Study
NYU Langone Health
NCT04580810
Telehealth Treatment for Alcohol Use Disorder
Ria Health
NCT05747703
Targeting Sleep Homeostasis to Improve Alcohol Use Disorder Treatment Outcomes (M-STAR Study)
University of Michigan
NCT04457674
Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 2
Mikhail N Koffarnus
NCT03942770
Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
Johns Hopkins University
NCT04620759
Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk
NYU Langone Health
NCT05828849
Alcoholic Liver Disease and the Gut Microbiome
University of California, Los Angeles
NCT05007470
EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope
Butler Hospital
NCT05074030
Early Intervention Following Sexual Assault
Medical University of South Carolina
NCT04582695
Improving Care for Unhealthy Alcohol Use in Primary Care
VA Office of Research and Development
NCT04565899
Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder
Louisiana State University Health Sciences Center in New Orleans
NCT05902754
Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC)
Mayo Clinic
NCT06319222
rTMS in Older Adults With MCI and AUD
Medical University of South Carolina
NCT05896332
Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder
Yale University
NCT05223829
Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism
Healing Advocacy Fund
NCT07189988
Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder
Peggy C Nopoulos
NCT05421065
Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Keith Heinzerling
NCT04410913
Diclofenac as a KMO Inhibitor
University of Maryland, Baltimore
NCT06029296
Apremilast for Alcohol Use Disorder Treatment in Women and Men
Yale University
NCT06324435
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
University of Pennsylvania
NCT05885594
Pilot rTMS for AUD+mTBI
VA Office of Research and Development
NCT03995173
Screening and Management of Unhealthy Alcohol Use in Primary Care
Virginia Commonwealth University
NCT04248023
Facilitating Use of the National Suicide Prevention Lifeline in Alcohol Patients (Reach Out)
University of Michigan
NCT04488055
Facilitating Alcohol Screening and Treatment (FAST)
University of Colorado, Denver
NCT04303676
Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19
University of Wisconsin, Madison
NCT05419128
HORIZANT (Gabapentin Enacarbil Extended-Release Tablets) for the Treatment of Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02252536
Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
Medical University of South Carolina
NCT03846505
Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers
New York State Psychiatric Institute
NCT03457077
Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action
Virginia Commonwealth University
NCT02900352
Alcohol and Cannabis Concentrates Co-Administration
University of Colorado, Denver
NCT05999344
Addressing Heavy Alcohol Use Consumption With Kudzu
Glenn-Milo Santos
NCT03709043
CM Treatment for Alcohol Dependence Using New Technology
UConn Health
NCT02143037
Ibudilast for the Treatment of Alcohol Use Disorder
University of California, Los Angeles
NCT03594435
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 26 |
| Phase 2 | 49 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcohol Use Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcohol Use Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcohol Use Disorder page
185 registered trials, 109 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 109 Alcohol Use Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Alcohol Use Disorder trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Use Disorder condition card totals 185 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.