Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03995173 · ClinicalTrials.gov registry record · Phase 2

Pilot rTMS for AUD+mTBI

A Phase 2 study of Post Traumatic Stress Disorder and Alcohol Use Disorder, sponsored by VA Office of Research and Development.

Active
Registry status
Phase 2
Development phase
1
Enrollment target
1
Study location

NCT03995173: Active Phase 2 study of Post Traumatic Stress Disorder and Alcohol Use Disorder, sponsored by VA Office of Research and Development.

NCT03995173 is a Phase 2 study of Post Traumatic Stress Disorder and Alcohol Use Disorder that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 1 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03995173, a Phase 2 study of Post Traumatic Stress Disorder and Alcohol Use Disorder, is active but no longer recruiting, sponsored by VA Office of Research and Development.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
1 participants
Enrollment target
1
Study location

Study Summary

This is a pilot randomized controlled trial (RCT) for Veteran participants with alcohol use disorder co-occurring with mild traumatic brain injury and/or post-traumatic stress disorder. The treatment intervention is repetitive Transcranial Magnetic Stimulation (rTMS) and the goal is to reduce alcohol craving with this treatment. The study will enroll 20 Veteran participants. Half of these participants will receive real rTMS and half of the participants will receive placebo rTMS. rTMS treatment will be provided over 10 sessions that will occur once every weekday for 2 weeks. Veteran participants will then complete follow-up phone calls to further evaluate alcohol craving and other symptoms.

Primary Outcome

5-item self-report measure of alcohol craving and each item is scored on a scale of 0 to 6. The minimum total score is 0 and the maximum is 30, indicating less to more severe alcohol craving, respectively.

Conditions Studied

Post Traumatic Stress Disorder Alcohol Use Disorder Mild Traumatic Brain Injury

Interventions

  • DEVICE repetitive transcranial magnetic stimulation

Study Locations (1)

Illinois

  • Edward Hines Jr. VA Hospital, Hines, IL - Hines

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2019-03-21
Est. Completion 2026-03-31
Phase Phase 2
VA Office of Research and Development

1,668 total trials

What the registry record for NCT03995173 still lists

NCT03995173 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which repetitive transcranial magnetic stimulation is the first listed.

NCT03995173 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT03995173 about?

NCT03995173 is a clinical study titled "Pilot rTMS for AUD+mTBI". This is a pilot randomized controlled trial (RCT) for Veteran participants with alcohol use disorder co-occurring with mild traumatic brain injury and/or post-traumatic stress disorder. The treatment intervention is repetitive Transcranial Magnetic Stimulation (rTMS) and the goal is to reduce alcoho...

What is the current status of trial NCT03995173?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2019-03-21. Estimated completion is 2026-03-31.

What conditions does trial NCT03995173 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Alcohol Use Disorder, Mild Traumatic Brain Injury.

What interventions are being tested in trial NCT03995173?

The interventions under investigation include: repetitive transcranial magnetic stimulation (DEVICE).

Who is sponsoring clinical trial NCT03995173?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03995173 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03995173's enrollment target sits among peer trials

1 263rd of 262 the lowest of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Related registry views

Source: ClinicalTrials.gov NCT03995173, the US trial registry maintained by the National Library of Medicine. NCT03995173 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.