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NCT06770556 · ClinicalTrials.gov registry record · NA

Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

A NA study of Alcohol Use Disorder and Alcohol Dependence, sponsored by Wake Forest University Health Sciences.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT06770556: Recruiting NA study of Alcohol Use Disorder and Alcohol Dependence, sponsored by Wake Forest University Health Sciences.

NCT06770556 is a NA study of Alcohol Use Disorder and Alcohol Dependence that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 10 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06770556, a NA study of Alcohol Use Disorder and Alcohol Dependence, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states. Extensive research has identified the general neural circuitry underlying AUD. There is an exciting opportunity to intervene in AUD using neuromodulation. Transcranial magnetic stimulation (TMS) offers a non-invasive method to modulate brain activity, making it a promising tool for investigating, modulating, and potentially treating AUD. However, the precise effects of TMS on neural circuits involved in AUD and the mechanisms underlying these effects must first be understood. Magnetoencephalography (MEG) is a neuroimaging method that provides direct measurement of brain activity within neural circuits with high temporal resolution. Critically, MEG can measure brain activity in a wide range of frequencies that are consistent with those targeted by TMS. The goal of this proposal is therefore to collect preliminary and feasibility data to support a future NIH grant application that would use MEG to investigate TMS effects in individuals with AUD (iAUD).

Primary Outcome

The number of potential adverse events queried after each TMS session.

Interventions

  • DEVICE Sham iTBS
  • DEVICE Active iTBS
  • DEVICE 10 Hz TMS
  • DEVICE 1 Hz TMS

Study Locations (1)

North Carolina

  • Wake Forest University Health Sciences - Winston-Salem

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-03-21
Est. Completion 2026-06-30
Phase NA
Wake Forest University Health Sciences

1,140 total trials

What NCT06770556 shows while recruiting

NCT06770556 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (97% lower).

The record links to 3 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 4 interventions - of which Sham iTBS is the first listed.

NCT06770556 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT06770556 about?

NCT06770556 is a clinical study titled "Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study". Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states. Extensive research has identified the general neural circuitry underlying AUD. There is an exciting opportunity to intervene in AUD usi...

What is the current status of trial NCT06770556?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-03-21. Estimated completion is 2026-06-30.

What conditions does trial NCT06770556 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Alcohol Dependence, Alcohol Consumption.

What interventions are being tested in trial NCT06770556?

The interventions under investigation include: Sham iTBS (DEVICE), Active iTBS (DEVICE), 10 Hz TMS (DEVICE), 1 Hz TMS (DEVICE).

Who is sponsoring clinical trial NCT06770556?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06770556 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Alcohol Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06770556's enrollment target sits among peer trials

10 181st of 184 higher than 3 of 184 other Alcohol Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06770556, the US trial registry maintained by the National Library of Medicine. NCT06770556 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.