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NCT06770556 · ClinicalTrials.gov registry record · NA

Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

A NA study of Alcohol Use Disorder and Alcohol Dependence, sponsored by Wake Forest University Health Sciences.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT06770556 is a NA study of Alcohol Use Disorder and Alcohol Dependence that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 10 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06770556, a NA study of Alcohol Use Disorder and Alcohol Dependence, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states. Extensive research has identified the general neural circuitry underlying AUD. There is an exciting opportunity to intervene in AUD using neuromodulation. Transcranial magnetic stimulation (TMS) offers a non-invasive method to modulate brain activity, making it a promising tool for investigating, modulating, and potentially treating AUD. However, the precise effects of TMS on neural circuits involved in AUD and the mechanisms underlying these effects must first be understood. Magnetoencephalography (MEG) is a neuroimaging method that provides direct measurement of brain activity within neural circuits with high temporal resolution. Critically, MEG can measure brain activity in a wide range of frequencies that are consistent with those targeted by TMS. The goal of this proposal is therefore to collect preliminary and feasibility data to support a future NIH grant application that would use MEG to investigate TMS effects in individuals with AUD (iAUD).

Interventions

  • DEVICE Sham iTBS
  • DEVICE Active iTBS
  • DEVICE 10 Hz TMS
  • DEVICE 1 Hz TMS

Study Locations (1)

North Carolina

  • Wake Forest University Health Sciences - Winston-Salem

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-03-21
Est. Completion 2026-06-30
Phase NA

Sponsor

Wake Forest University Health Sciences

1,140 total trials

What the Registry Record Tells You About NCT06770556

The ClinicalTrials.gov registry entry for NCT06770556 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (97% lower). The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 4 interventions - of which Sham iTBS is the first listed.

NCT06770556 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT06770556 about?

NCT06770556 is a clinical study titled "Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study". Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states. Extensive research has identified the general neural circuitry underlying AUD. There is an exciting opportunity to intervene in AUD usi...

What is the current status of trial NCT06770556?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-03-21. Estimated completion is 2026-06-30.

What conditions does trial NCT06770556 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Alcohol Dependence, Alcohol Consumption.

What interventions are being tested in trial NCT06770556?

The interventions under investigation include: Sham iTBS (DEVICE), Active iTBS (DEVICE), 10 Hz TMS (DEVICE), 1 Hz TMS (DEVICE).

Who is sponsoring clinical trial NCT06770556?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06770556 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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