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NCT05885594 · ClinicalTrials.gov registry record · Early Phase 1
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
A Early Phase 1 study of Alcohol Use Disorder, sponsored by University of Pennsylvania.
- Active
- Registry status
- Early Phase 1
- Development phase
- 4
- Enrollment target
- 1
- Study location
NCT05885594: Active Early Phase 1 study of Alcohol Use Disorder, sponsored by University of Pennsylvania.
NCT05885594 is a Early Phase 1 study of Alcohol Use Disorder that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 4 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05885594, a Early Phase 1 study of Alcohol Use Disorder, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 4 participants
- Enrollment target
- 1
- Study location
Study Summary
Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30). PET/CT imaging will be used to evaluate brain and whole-body inflammation using the investigational radiotracer \[18F\]NOS. All participants will have one \[18F\]NOS positron emission tomography/ computed tomography (PET/CT) scan performed.
Primary Outcome
The primary outcome measure to be analyzed is a comparisons of AUD subjects and healthy control subjects in the amount of \[18F\]NOS uptake (distribution volume) in brain and heart.
Conditions Studied
Interventions
- DRUG [18F]NOS
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2023-08-08 |
| Est. Completion | 2027-03-15 |
| Phase | Early Phase 1 |
What the registry record for NCT05885594 still lists
NCT05885594 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which [18F]NOS is the first listed.
NCT05885594 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05885594 about?
NCT05885594 is a clinical study titled "Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study". Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30). PET/CT imaging will be used to evaluate brain and whole-body inflammation using the investigational radiotracer \[18F\]NOS. All participants will have...
What is the current status of trial NCT05885594?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 4 participants. The study started on 2023-08-08. Estimated completion is 2027-03-15.
What conditions does trial NCT05885594 study?
This clinical trial studies the following conditions: Alcohol Use Disorder.
What interventions are being tested in trial NCT05885594?
The interventions under investigation include: [18F]NOS (DRUG).
Who is sponsoring clinical trial NCT05885594?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05885594 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05885594's enrollment target sits among peer trials
4 184th of 184 higher than 1 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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