Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05943665 · ClinicalTrials.gov registry record · Phase 2

MDMA for AUD/PTSD Comorbidity

A Phase 2 study of Alcohol Use Disorder and Post Traumatic Stress Disorder, sponsored by Carolina L Haass-Koffler.

Recruiting
Registry status
Phase 2
Development phase
18
Enrollment target
1
Study location

NCT05943665 is a Phase 2 study of Alcohol Use Disorder and Post Traumatic Stress Disorder that is actively recruiting participants, run by Carolina L Haass-Koffler. The registered enrollment target is 18 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05943665, a Phase 2 study of Alcohol Use Disorder and Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Carolina L Haass-Koffler.

RECRUITING
Registry status
Phase 2
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

The study investigators are conducting the first open label pilot trial of MDMA-assisted therapy (MDMA-AT) with a comorbid sample of military veterans with a comorbid diagnosis of Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD). This novel experimental treatment package consists of two once-monthly Experimental Sessions of therapy combined with a divided-dose of MDMA HCl, along with non-drug preparatory and integrative therapy. The Primary Outcome measure, the Timeline Follow-back (TLFB), will evaluate changes in alcohol use over time. Changes in PTSD symptoms will also be evaluated.

Conditions Studied

Alcohol Use Disorder Post Traumatic Stress Disorder

Interventions

  • DRUG MDMA

Study Locations (1)

Rhode Island

  • Brown University - Providence

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2024-02-06
Est. Completion 2026-01-30
Phase Phase 2

Sponsor

Carolina L Haass-Koffler

1 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05943665

The ClinicalTrials.gov registry entry for NCT05943665 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (95% lower). The listed sponsor is Carolina L Haass-Koffler, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which MDMA is the first listed.

NCT05943665 reports 1 study location spanning 1 distinct geographic area - top geographies include Rhode Island.

Frequently Asked Questions

What is clinical trial NCT05943665 about?

NCT05943665 is a clinical study titled "MDMA for AUD/PTSD Comorbidity". The study investigators are conducting the first open label pilot trial of MDMA-assisted therapy (MDMA-AT) with a comorbid sample of military veterans with a comorbid diagnosis of Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD). This novel experimental treatment package consists...

What is the current status of trial NCT05943665?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2024-02-06. Estimated completion is 2026-01-30.

What conditions does trial NCT05943665 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Post Traumatic Stress Disorder.

What interventions are being tested in trial NCT05943665?

The interventions under investigation include: MDMA (DRUG).

Who is sponsoring clinical trial NCT05943665?

This trial is sponsored by Carolina L Haass-Koffler, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05943665 being conducted?

This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Alcohol Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Alcohol Use Disorder

All registered trials for this condition

Post Traumatic Stress Disorder

All registered trials for this condition

Rhode Island

All trials with a study site in Rhode Island

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.