Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Use Disorder: early-phase trial registry
109 of 185 indexed Alcohol Use Disorder trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #60 of 28,707 conditions by registered trial count.
185 US clinical trials · 109 currently recruiting · #60 of 28,707 conditions by registered trial count
Alcohol Use Disorder: 185 US clinical trials tracked, 109 recruiting.
Alcohol Use Disorder is the subject of 185 registered US clinical trials on ClinicalTrials.gov, 109 of them currently open to new participants. 8 are in Phase 3-4 (later-stage) and 75 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 13 of these trials.
Enrollment posture brief
Registry condition alcohol-use-disorder
OPEN 109 | RECR 59% | LATE 8 | EARLY 75 | RANK #60 | SPON 13
Volume-matched condition peers
Nearest open-share peer: Breast Carcinoma (59% recruiting · 107 trials)
Alcohol Use Disorder lists 109 open slots (59% of 185 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Alcohol Use Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Alcohol Use Disorder is recruiting above its size-band peers.
109 of 185 indexed trials (58.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Alcohol Use Disorder trials is spread across many organizations.
Yale University accounts for 13 of 185 trials (7%). 91 distinct sponsors appear on at least one study for this condition label.
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Typical Alcohol Use Disorder enrolment sits around 90 participants.
Median target enrolment is 90 among the 185 trials that report a genuine target (sentinel values excluded). 99 of those (53.5%) plan for fewer than 100 participants.
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Alcohol Use Disorder research is mostly interventional.
173 interventional and 12 observational studies make up this index (93.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
185 total, page 4 of 4
Alcohol Misuse Intervention in Active Duty US Navy Personnel
University of New Mexi
NCT04893044
Cannabidiol as a Treatment for AUD Comorbid With PTSD
NYU Langone Health
NCT03248167
The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders
Yale University
NCT03872128
Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control
Medical University of South Carolina
NCT02949934
Substance Use Treatment and Recovery Team (START)
RAND
NCT04314648
Effect of CBT Microinterventions on Mechanisms of Behavior Change Among Adults With AUD
University of Massachusetts, Worcester
NCT03661853
Orexin Receptor Antagonists as Modulators of Threat Sensitivity in Individuals With Alcohol Use Disorder
Ohio State University
NCT05656534
Dual Reinforcement Contingency Management for Alcohol Use Disorders
UConn Health
NCT04064463
Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder
University of Wisconsin, Madison
NCT04059549
Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies
Kent State University
NCT04286867
Acute Alcohol Response In Bipolar Disorder: a fMRI Study
University of Texas at Austin
NCT04063384
Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics
Medical University of South Carolina
NCT03220776
Medication Development in Alcoholism: Apremilast Versus Placebo
The Scripps Research Institute
NCT03175549
Medication Development for Protracted Abstinence in Alcoholism: CORT118335 Versus Placebo
The Scripps Research Institute
NCT04466215
Semaglutide for Alcohol Use Disorder
University of North Carolina, Chapel Hill
NCT05520775
Human Laboratory Study of Varenicline for Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT03035708
MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study
Boston Medical Center
NCT03718104
CBD for the Treatment of Alcohol Use Disorder
University of Colorado, Denver
NCT04873453
Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in Veterans
VA Office of Research and Development
NCT04574167
Study of Sunobinop on Craving in Alcohol Use Disorder
Imbrium Therapeutics
NCT06545929
Acamprosate Initiated During Alcohol Detoxification
Forest Laboratories
NCT00360594
[C-11]PiB PET Imaging in Alcohol Use Disorders
University of Pittsburgh
NCT03746366
EMPOWER AUD Pivotal Trial
Theranova, L.L.C.
NCT05948605
Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
Seattle Institute for Biomedical and Clinical Research
NCT02322047
Addiction Treatment Outcome Monitoring Study
University of Washington
NCT04155385
Families With Substance Use and Psychosis: A Pilot Study
Mclean Hospital
NCT04284813
Effects of Cannabidiol in Alcohol Use Disorder
NYU Langone Health
NCT03252756
Treatment Parameters for the Empower Neuromodulation System (ENS)
Theranova, L.L.C.
NCT03807544
Phosphatidylethanol-Based Contingency Management for Housing
Washington State University
NCT04038021
Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
University of Massachusetts, Worcester
NCT03845985
Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.
University of Pittsburgh
NCT02185131
Modafinil for the Treatment of Alcohol Use Disorders
The Mind Research Network
NCT03424681
Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
University of Pittsburgh
NCT02646449
Oxytocin and Stress Response in Alcohol Use Disorder
Medical University of South Carolina
NCT03610633
CCTAP: Cognitive Control Training for Treatment of AUD-PTSD
Posit Science Corporation
NCT03200028
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 26 |
| Phase 2 | 49 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Alcohol Use Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Alcohol Use Disorder trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Alcohol Use Disorder page
185 registered trials, 109 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 109 Alcohol Use Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Alcohol Use Disorder trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Alcohol Use Disorder condition card totals 185 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.