Vanderbilt University Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Vanderbilt University Medical Center sits in the top decile of US sponsors by registered trial count (#51 of 15,742 sponsors by registered trial count).

677 total trials 130 currently recruiting 400 completed early-phase tilt top decile by trial count

Vanderbilt University Medical Center: 677 sponsored US clinical trials, 130 recruiting.

Vanderbilt University Medical Center sponsors 677 registered US clinical trials on ClinicalTrials.gov, 130 of them currently recruiting, and 400 completed. 70 of these trials are in Phase 3-4 (later-stage) and 127 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Autonomic Failure, with 9 trials.

Top-decile sponsor footprint

Vanderbilt University Medical Center ranks in the top decile of sponsors by registered trial count (#51 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 54/100

400 of 467 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

677 total, page 4 of 14

ACTIVE NOT RECRUITING

Family History and Cancer Risk Study

NCT05079334

ACTIVE NOT RECRUITING Phase 1

Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

NCT04769206

ACTIVE NOT RECRUITING Phase 2

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

NCT04713982

ACTIVE NOT RECRUITING NA

Competency Based Approaches for Community Health 2

NCT04971044

ACTIVE NOT RECRUITING NA

Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula

NCT04782817

ACTIVE NOT RECRUITING NA

Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

NCT04996173

ACTIVE NOT RECRUITING NA

COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) Study

NCT04889417

ACTIVE NOT RECRUITING Phase 1

Salt-Sensitivity and Immunity Cell Activation

NCT03753204

ACTIVE NOT RECRUITING

Improving Diagnostic Accuracy for Acute Heart Failure

NCT04886128

ACTIVE NOT RECRUITING Early Phase 1

Autonomic Determinants of POTS - Pilot 2

NCT04140721

ACTIVE NOT RECRUITING Phase 2

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

NCT05231798

ACTIVE NOT RECRUITING

Post Acute Sequelae of COVID-19

NCT04964115

ACTIVE NOT RECRUITING NA

Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer

NCT04922307

ACTIVE NOT RECRUITING Phase 4

Cognitive Outcomes in Stable Renal Transplant Patients Switched FromTacrolimus to Envarsus XR™

NCT04838288

ACTIVE NOT RECRUITING Phase 4

Comparison Study of LMX4 Cream Versus J-Tip Needle-Free Injection System With Lidocaine for In-Office PAT for Clubfoot

NCT04766684

ACTIVE NOT RECRUITING

Stroke Prevention in Young Adults With Sickle Cell Anemia

NCT04808778

ACTIVE NOT RECRUITING Phase 2

Dopaminergic Dysfunction in Late-Life Depression

NCT04469959

ACTIVE NOT RECRUITING NA

Functional Electrical Stimulation of the Bilaterally Paralyzed Human Larynx

NCT04028674

ACTIVE NOT RECRUITING Phase 2

High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients

NCT04613206

ACTIVE NOT RECRUITING Phase 2

Omega-3 Fatty Acids for Smoking Cessation in Pregnancy

NCT04417595

ACTIVE NOT RECRUITING

Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction in ICU Survivors, 2nd Study

NCT04305600

ACTIVE NOT RECRUITING Phase 2

Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old

NCT04551170

ACTIVE NOT RECRUITING Early Phase 1

Quantitative Imaging of Brain Glymphatic Function in Humans

NCT04768101

ACTIVE NOT RECRUITING

Combinatorial Single Cell Strategies for a Crohn's Disease Gut Cell Atlas

NCT04113733

ACTIVE NOT RECRUITING

Activity Monitoring in Pulmonary Hypertension

NCT04101630

ACTIVE NOT RECRUITING NA

A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)

NCT03927820

ACTIVE NOT RECRUITING Early Phase 1

Autonomic Determinants of POTS - Pilot1

NCT04050410

ACTIVE NOT RECRUITING

Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers

NCT04036305

ACTIVE NOT RECRUITING

CMV T Cell Immunity in Pediatric Solid Organ Transplant Recipients

NCT03924219

ACTIVE NOT RECRUITING

Addressing Post-Intensive Care Syndrome Among Survivors of COVID (APICS-COVID)

NCT03738774

ACTIVE NOT RECRUITING Phase 2

Theophylline Treatment for Pseudohypoparathyroidism

NCT03029429

ACTIVE NOT RECRUITING Phase 2

Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus

NCT03527472

ACTIVE NOT RECRUITING Early Phase 1

Noninvasive Markers of Functional Nausea in Children

NCT03593811

ACTIVE NOT RECRUITING NA

Surgery for Cancer With Option of Palliative Care Expert

NCT03436290

ACTIVE NOT RECRUITING

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study

NCT03098459

ACTIVE NOT RECRUITING Phase 1

Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

NCT03318094

ACTIVE NOT RECRUITING Phase 1

Vagal Stimulation in POTS

NCT03124355

ACTIVE NOT RECRUITING

The HIV, Adipose Tissue Immunology, and Metabolism Study

NCT04451980

ACTIVE NOT RECRUITING Phase 1

Incidence of Acute Laryngeal Injury Following Endotracheal Intubation

NCT03250975

ACTIVE NOT RECRUITING

POTS NET mRNA Functional Correlation With NET Activity

NCT03218761

ACTIVE NOT RECRUITING

Epidemiology of Silent and Overt Strokes in Sickle Cell Disease

NCT03376893

ACTIVE NOT RECRUITING

Measuring Outcomes of Activity in Intensive Care

NCT03115840

ACTIVE NOT RECRUITING Early Phase 1

Modafinil and Cognitive Function in POTS

NCT01988883

ACTIVE NOT RECRUITING NA

Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

NCT01000350

ACTIVE NOT RECRUITING

ExploR™ Modular Radial Head Data Collection

NCT00521846

ACTIVE NOT RECRUITING

The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors

NCT00392795

ACTIVE NOT RECRUITING

Evaluation of Cerebral Spinal Fluid and Blood in Patients With Subarachnoid Hemorrhage

NCT00593268

ACTIVE NOT RECRUITING

Multicenter Orthopaedics Outcomes Network for ACL Reconstructions

NCT00463099

NOT YET RECRUITING

Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - Cornea

NCT05210478

NOT YET RECRUITING NA

Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing.

NCT07685977

← Previous Page 4 of 14 Next →

Phase Distribution

PhaseTrial count
Phase 1 65
Phase 2 62
Phase 3 14
Phase 4 56

What is open in the Vanderbilt University Medical Center pipeline

130 recruiting of 677 indexed (19% open); 400 completed (59%).

Phase mix: 70 late (III/IV) vs 127 early (I/II) (early-phase heavy).

Top condition: Autonomic Failure (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Vanderbilt University Medical Center: open-pipeline peers nationwide

Peers matched on 677 registered trials and 19% open enrollment, not the therapeutic-area sidebar.

Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 01,0002,0003,000 12%14%16%18%20%22%24% Total trials Recruiting share Vanderbilt University Medical CenterThe Cleveland ClinicUniversity of California, DavisWeill Medical College of Cornell UniversityIcahn School of Medicine at Mount SinaiCalifornia Polytechnic State University-San Luis ObispoPhoenix Children's HospitalMayo ClinicUniversity of South Carolina
Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Vanderbilt University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 677 trials (± recruiting share)

Sponsors near 19% open enrollment (± trial volume)

What to do with this Vanderbilt University Medical Center page

677 registered trials is a research-attention snapshot, not an endorsement of Vanderbilt University Medical Center or any single study.

  • 130 of Vanderbilt University Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Autonomic Failure is the condition Vanderbilt University Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Autonomic Failure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Vanderbilt University Medical Center pipeline card: 677 registered trials from official public datasets.Report a data error.