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NCT04782817 · ClinicalTrials.gov registry record · NA

Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula

A NA study of Intubation and Cardiovascular Surgical Procedure, sponsored by Vanderbilt University Medical Center.

Active
Registry status
NA
Development phase
3,568
Enrollment target
1
Study location

NCT04782817 is a NA study of Intubation and Cardiovascular Surgical Procedure that is active but no longer recruiting, run by Vanderbilt University Medical Center. The registered enrollment target is 3,568 participants, above the 1,990-participant average among 4 other Intubation trials with a reported enrollment target (79% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT04782817, a NA study of Intubation and Cardiovascular Surgical Procedure, is active but no longer recruiting, sponsored by Vanderbilt University Medical Center.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
3,568 participants
Enrollment target
1
Study location

Study Summary

The iCAN trial is a pragmatic randomized controlled trial that aims to test the hypothesis that HFNC versus usual care oxygenation strategies applied immediately after initial extubation after cardiac surgery decreases the all-cause 48-hour reintubation rate (extubation failure within 48 hours of initial extubation).

Interventions

  • OTHER Recommendation for high flow nasal cannula oxygen therapy order set
  • OTHER Provider choice standard care order set

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 3,568 participants
Start Date 2021-11-01
Est. Completion 2026-03
Phase NA

What the Registry Record Tells You About NCT04782817

The ClinicalTrials.gov registry entry for NCT04782817 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 3,568 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,990-participant average among 4 other Intubation trials with a reported enrollment target (79% higher). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Intubation appearing as the primary indexed condition, and to 2 interventions - of which Recommendation for high flow nasal cannula oxygen therapy order set is the first listed.

NCT04782817 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT04782817 about?

NCT04782817 is a clinical study titled "Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula". The iCAN trial is a pragmatic randomized controlled trial that aims to test the hypothesis that HFNC versus usual care oxygenation strategies applied immediately after initial extubation after cardiac surgery decreases the all-cause 48-hour reintubation rate (extubation failure within 48 hours of in...

What is the current status of trial NCT04782817?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 3,568 participants. The study started on 2021-11-01. Estimated completion is 2026-03.

What conditions does trial NCT04782817 study?

This clinical trial studies the following conditions: Intubation, Cardiovascular Surgical Procedure.

What interventions are being tested in trial NCT04782817?

The interventions under investigation include: Recommendation for high flow nasal cannula oxygen therapy order set (OTHER), Provider choice standard care order set (OTHER).

Who is sponsoring clinical trial NCT04782817?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04782817 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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