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NCT03098459 · ClinicalTrials.gov registry record
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
A clinical trial of Traumatic Brain Injury and Cognitive Impairment, sponsored by Vanderbilt University Medical Center.
- Active
- Registry status
- 432
- Enrollment target
- 1
- Study location
NCT03098459: Active study of Traumatic Brain Injury and Cognitive Impairment, sponsored by Vanderbilt University Medical Center.
NCT03098459 is a study of Traumatic Brain Injury and Cognitive Impairment that is active but no longer recruiting, run by Vanderbilt University Medical Center. The registered enrollment target is 432 participants, above the 275-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (57% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03098459, a study of Traumatic Brain Injury and Cognitive Impairment, is active but no longer recruiting, sponsored by Vanderbilt University Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 432 participants
- Enrollment target
- 1
- Study location
Study Summary
Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease, and traumatic brain injury. The INSIGHT-ICU Study (Illuminating Neuropsychological dysfunction and Systemic Inflammatory mechanisms Gleaned after Hospitalization in Trauma-ICU Study) is the first comprehensive and longitudinal long-term cognitive impairment study after traumatic injury. The societal impact of long-term cognitive impairment after trauma is immense given that these patients are young and constitute a large proportion of employable adults.
Primary Outcome
LTCI (Long-term Cognitive Impairment) as measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
Conditions Studied
Interventions
- OTHER Non-interventional observational prospective cohort study
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 432 participants |
| Start Date | 2017-11-02 |
| Est. Completion | 2027-10 |
What the registry record for NCT03098459 still lists
NCT03098459 is an observational study that tracks outcomes without assigning an intervention. The registered 432 participants enrollment target is mid-sized for trials with a published cap, above the 275-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (57% higher).
The record links to 8 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 1 intervention - of which Non-interventional observational prospective cohort study is the first listed.
NCT03098459 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT03098459 about?
NCT03098459 is a clinical study titled "Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study". Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease, and traumatic brain injury. The INSIGHT-ICU Study (Illuminating Neurops...
What is the current status of trial NCT03098459?
This trial is currently active not recruiting. The enrollment target is 432 participants. The study started on 2017-11-02. Estimated completion is 2027-10.
What conditions does trial NCT03098459 study?
This clinical trial studies the following conditions: Traumatic Brain Injury, Cognitive Impairment, Critical Illness, Delirium, Trauma.
What interventions are being tested in trial NCT03098459?
The interventions under investigation include: Non-interventional observational prospective cohort study (OTHER).
Who is sponsoring clinical trial NCT03098459?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03098459 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Traumatic Brain Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03098459's enrollment target sits among peer trials
432 17th of 171 higher than 155 of 171 other Traumatic Brain Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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