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NCT01988883 · ClinicalTrials.gov registry record · Early Phase 1

Modafinil and Cognitive Function in POTS

A Early Phase 1 study of Postural Tachycardia Syndrome, sponsored by Vanderbilt University Medical Center.

Active
Registry status
Early Phase 1
Development phase
20
Enrollment target
1
Study location

NCT01988883 is a Early Phase 1 study of Postural Tachycardia Syndrome that is active but no longer recruiting, run by Vanderbilt University Medical Center. The registered enrollment target is 20 participants, below the 82-participant average among 19 other Postural Tachycardia Syndrome trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01988883, a Early Phase 1 study of Postural Tachycardia Syndrome, is active but no longer recruiting, sponsored by Vanderbilt University Medical Center.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood. The purpose of this study is to better understand the cognitive dysfunction associated POTS, and to determine optimal treatment strategies for this condition. In this study, the investigators will test the hypothesis that acute administration of the psychostimulant drug modafinil can improve seated measures of cognitive function in patients with POTS.

Conditions Studied

Postural Tachycardia Syndrome

Interventions

  • DRUG Placebo
  • DRUG Modafinil
  • DRUG Propranolol

Study Locations (1)

Tennessee

  • Vanderbilt University - Nashville

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2014-10
Est. Completion 2026-12
Phase Early Phase 1

Sponsor

Vanderbilt University Medical Center

677 total trials

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What the Registry Record Tells You About NCT01988883

The ClinicalTrials.gov registry entry for NCT01988883 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 82-participant average among 19 other Postural Tachycardia Syndrome trials with a reported enrollment target (76% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Postural Tachycardia Syndrome appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT01988883 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT01988883 about?

NCT01988883 is a clinical study titled "Modafinil and Cognitive Function in POTS". A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood. The purpose of this study is to better understand the cognitive dysfunction associated POTS, and to determine optimal treatment strategies for t...

What is the current status of trial NCT01988883?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2014-10. Estimated completion is 2026-12.

What conditions does trial NCT01988883 study?

This clinical trial studies the following conditions: Postural Tachycardia Syndrome.

What interventions are being tested in trial NCT01988883?

The interventions under investigation include: Placebo (DRUG), Modafinil (DRUG), Propranolol (DRUG).

Who is sponsoring clinical trial NCT01988883?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01988883 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.