VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 8 of 34

ACTIVE NOT RECRUITING Phase 3

Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

NCT03654053

ACTIVE NOT RECRUITING NA

Collaborative Specialty Care for Gulf War Illness

NCT04403295

ACTIVE NOT RECRUITING

Direct Referral for Apnea Monitoring

NCT05419323

ACTIVE NOT RECRUITING NA

Addressing Sleep Apnea Post-Stroke/TIA

NCT04322162

ACTIVE NOT RECRUITING Phase 1

MitoQ for Fatigue in Multiple Sclerosis (MS)

NCT04267926

ACTIVE NOT RECRUITING NA

Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke

NCT04116671

ACTIVE NOT RECRUITING NA

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

NCT04064086

ACTIVE NOT RECRUITING Phase 2

A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation

NCT04104893

ACTIVE NOT RECRUITING NA

Non-invasive Nerve Stimulation and Sleep

NCT04021537

ACTIVE NOT RECRUITING Phase 4

Pentoxifylline in Diabetic Kidney Disease

NCT03625648

ACTIVE NOT RECRUITING

Imaging to Improve Brain Stimulation

NCT04016402

ACTIVE NOT RECRUITING Phase 4

Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism

NCT03887936

ACTIVE NOT RECRUITING

Improving Brain Stimulation Through Imaging

NCT03851380

ACTIVE NOT RECRUITING NA

Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics

NCT03477435

ACTIVE NOT RECRUITING NA

Exercise Rehabilitation in Veteran Cancer Survivors

NCT03621813

ACTIVE NOT RECRUITING Phase 4

Novel Combination Therapy for Osteoporosis in Men

NCT03994172

ACTIVE NOT RECRUITING

Health Information for Infected Veterans

NCT03190317

ACTIVE NOT RECRUITING NA

Aerobic Exercise and Cerebrovascular Function

NCT03803904

ACTIVE NOT RECRUITING Phase 2

Pilot rTMS for AUD+mTBI

NCT03995173

ACTIVE NOT RECRUITING NA

Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes

NCT03508934

ACTIVE NOT RECRUITING Phase 3

Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests

NCT03539614

ACTIVE NOT RECRUITING NA

A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging

NCT03445559

ACTIVE NOT RECRUITING NA

Mild TBI Assessment & Rehabilitation

NCT02920788

ACTIVE NOT RECRUITING NA

Blood Flow Monitoring to Prevent Post-Polypectomy Induced Ulcer Bleeding

NCT02875353

ACTIVE NOT RECRUITING NA

Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications

NCT02694185

ACTIVE NOT RECRUITING

Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation

NCT03625349

ACTIVE NOT RECRUITING NA

Resistive Training Combined With Nutritional Therapy After Stroke

NCT02347995

ACTIVE NOT RECRUITING NA

Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation

NCT02911805

ACTIVE NOT RECRUITING NA

LED Treatment to Improve Cognition and Promote Recovery in TBI

NCT02404402

ACTIVE NOT RECRUITING

Gulf War Era Cohort and Biorepository

NCT01803854

ACTIVE NOT RECRUITING NA

Improving Autonomic Function and Balance in Diabetic Neuropathy

NCT01864460

ACTIVE NOT RECRUITING NA

Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)

NCT01239082

ACTIVE NOT RECRUITING NA

Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)

NCT01138020

ACTIVE NOT RECRUITING

Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study

NCT00748995

NOT YET RECRUITING Phase 1

Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care

NCT07456150

NOT YET RECRUITING NA

The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans

NCT06746727

NOT YET RECRUITING NA

Perinatal Peer Support for Veterans With Serious Mental Illness

NCT07362576

NOT YET RECRUITING Phase 1

Device for Bladder Control for Men With SCI

NCT07668063

NOT YET RECRUITING NA

Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans

NCT06766331

NOT YET RECRUITING NA

Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury

NCT07217808

NOT YET RECRUITING NA

ACT for Veterans With IBD and Mental Health Challenges

NCT07397195

NOT YET RECRUITING NA

Pilot Randomized Trial of BA-GSH in VA PC-MHI

NCT07541482

NOT YET RECRUITING NA

Behavior Therapy vs Education for Persistent Headache After Mild TBI

NCT07229391

NOT YET RECRUITING NA

Developing and Piloting an Implementation Strategy for a Brief, Motivational Interviewing-based Lethal Means Safety Counseling Intervention in Primary Care Settings

NCT07247916

NOT YET RECRUITING Phase 2

Cognitive Training for Functioning in PTSD

NCT07693686

NOT YET RECRUITING NA

Fall Prevention in Mild Cognitive Impairment

NCT07507812

NOT YET RECRUITING Phase 2

Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator

NCT07414537

NOT YET RECRUITING NA

A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms

NCT06689787

NOT YET RECRUITING NA

Testing a Peer-Support Group for Veterans Who Hear Voices

NCT07555275

NOT YET RECRUITING NA

Implementation of Routine Walking Speed Measurements in Older Veterans

NCT07513805

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.