VA Office of Research and Development
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).
VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.
VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.
Top-decile sponsor footprint
VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
1,668 total, page 8 of 34
Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis
NCT03654053
Collaborative Specialty Care for Gulf War Illness
NCT04403295
Direct Referral for Apnea Monitoring
NCT05419323
Addressing Sleep Apnea Post-Stroke/TIA
NCT04322162
MitoQ for Fatigue in Multiple Sclerosis (MS)
NCT04267926
Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
NCT04116671
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
NCT04064086
A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation
NCT04104893
Non-invasive Nerve Stimulation and Sleep
NCT04021537
Pentoxifylline in Diabetic Kidney Disease
NCT03625648
Imaging to Improve Brain Stimulation
NCT04016402
Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism
NCT03887936
Improving Brain Stimulation Through Imaging
NCT03851380
Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics
NCT03477435
Exercise Rehabilitation in Veteran Cancer Survivors
NCT03621813
Novel Combination Therapy for Osteoporosis in Men
NCT03994172
Health Information for Infected Veterans
NCT03190317
Aerobic Exercise and Cerebrovascular Function
NCT03803904
Pilot rTMS for AUD+mTBI
NCT03995173
Continuous Glucose Monitoring Devices in Hospitalized Veterans With Diabetes
NCT03508934
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
NCT03539614
A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging
NCT03445559
Mild TBI Assessment & Rehabilitation
NCT02920788
Blood Flow Monitoring to Prevent Post-Polypectomy Induced Ulcer Bleeding
NCT02875353
Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications
NCT02694185
Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation
NCT03625349
Resistive Training Combined With Nutritional Therapy After Stroke
NCT02347995
Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation
NCT02911805
LED Treatment to Improve Cognition and Promote Recovery in TBI
NCT02404402
Gulf War Era Cohort and Biorepository
NCT01803854
Improving Autonomic Function and Balance in Diabetic Neuropathy
NCT01864460
Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
NCT01239082
Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)
NCT01138020
Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study
NCT00748995
Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care
NCT07456150
The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans
NCT06746727
Perinatal Peer Support for Veterans With Serious Mental Illness
NCT07362576
Device for Bladder Control for Men With SCI
NCT07668063
Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans
NCT06766331
Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury
NCT07217808
ACT for Veterans With IBD and Mental Health Challenges
NCT07397195
Pilot Randomized Trial of BA-GSH in VA PC-MHI
NCT07541482
Behavior Therapy vs Education for Persistent Headache After Mild TBI
NCT07229391
Developing and Piloting an Implementation Strategy for a Brief, Motivational Interviewing-based Lethal Means Safety Counseling Intervention in Primary Care Settings
NCT07247916
Cognitive Training for Functioning in PTSD
NCT07693686
Fall Prevention in Mild Cognitive Impairment
NCT07507812
Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator
NCT07414537
A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms
NCT06689787
Testing a Peer-Support Group for Veterans Who Hear Voices
NCT07555275
Implementation of Routine Walking Speed Measurements in Older Veterans
NCT07513805
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 89 |
| Phase 2 | 147 |
| Phase 3 | 55 |
| Phase 4 | 69 |
Therapeutic Areas
What is open in the VA Office of Research and Development pipeline
291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).
Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).
Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
VA Office of Research and Development: open-pipeline peers nationwide
Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 1,668 trials (± recruiting share)
- University of California, San Francisco · 1,713 trials · 16% recruiting
- Duke University · 1,725 trials · 11% recruiting
- Stanford University · 1,744 trials · 15% recruiting
- Washington University School of Medicine · 1,502 trials · 14% recruiting
Sponsors near 17% open enrollment (± trial volume)
- University of South Florida · 17% recruiting · 252 trials
- ImmunityBio · 17% recruiting · 46 trials
- Old Dominion University · 17% recruiting · 23 trials
- Texas Tech University · 17% recruiting · 69 trials
Related
What to do with this VA Office of Research and Development page
1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.
- 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.