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ACTIVE NOT RECRUITING Phase 4

Pentoxifylline in Diabetic Kidney Disease

NCT03625648 · View on ClinicalTrials.gov ↗

Study Summary

Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a study to bee conducted in 40 VA hospitals across the nation to determine definitively whether or not PTX can prevent worsening of kidney disease and delay death in patients with diabetic kidney disease.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Pentoxifylline

Study Locations (20)

California

  • VA Loma Linda Healthcare System, Loma Linda, CA — Loma Linda
  • VA Long Beach Healthcare System, Long Beach, CA — Long Beach
  • VA Palo Alto Health Care System, Palo Alto, CA — Palo Alto

Florida

  • Bay Pines VA Healthcare System, Pay Pines, FL — Bay Pines
  • North Florida/South Georgia Veterans Health System, Gainesville, FL — Gainesville
  • James A. Haley Veterans' Hospital, Tampa, FL — Tampa

Missouri

  • Harry S. Truman Memorial, Columbia, MO — Columbia
  • Kansas City VA Medical Center, Kansas City, MO — Kansas City
  • St. Louis VA Medical Center John Cochran Division, St. Louis, MO — St Louis

Arizona

  • Phoenix VA Health Care System, Phoenix, AZ — Phoenix

Arkansas

  • Central Arkansas Veterans Healthcare System, Little Rock, AR — Little Rock

Colorado

  • Rocky Mountain Regional VA Medical Center, Aurora, CO — Aurora

Georgia

  • Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur

Illinois

  • Edward Hines Jr. VA Hospital, Hines, IL — Hines

Trial Details

FieldValue
Enrollment Target 2,376 participants
Start Date 2019-11-18
Est. Completion 2030-07-08
Phase Phase 4

Sponsor

VA Office of Research and Development

1,863 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03625648

The ClinicalTrials.gov registry entry for NCT03625648 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,376 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,863 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Diabetic Kidney Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03625648 reports 20 study locations spanning 14 distinct geographic areas — top geographies include California, Florida, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03625648 about?

NCT03625648 is a clinical study titled "Pentoxifylline in Diabetic Kidney Disease". Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a stud...

What is the current status of trial NCT03625648?

This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 2,376 participants. The study started on 2019-11-18. Estimated completion is 2030-07-08.

What conditions does trial NCT03625648 study?

This clinical trial studies the following conditions: Diabetic Kidney Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03625648?

The interventions under investigation include: Placebo (DRUG), Pentoxifylline (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03625648?

This trial is sponsored by VA Office of Research and Development, which has 1,863 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03625648 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial