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NCT04016402 · ClinicalTrials.gov registry record
Imaging to Improve Brain Stimulation
A clinical trial of Depressive Disorder, sponsored by VA Office of Research and Development.
- Active
- Registry status
- 42
- Enrollment target
- 2
- Study locations
NCT04016402: Active study of Depressive Disorder, sponsored by VA Office of Research and Development.
NCT04016402 is a study of Depressive Disorder that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 42 participants, below the 331-participant average among 47 other Depressive Disorder trials with a reported enrollment target (87% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04016402, a study of Depressive Disorder, is active but no longer recruiting, sponsored by VA Office of Research and Development.
- ACTIVE NOT RECRUITING
- Registry status
- 42 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS). People who receive rTMS will have pictures of their brains and brain activity taken by a magnetic resonance imaging (MRI) scanner before and after their treatment, as well as up to three times during the six-week treatment course. These images will be examined to see if the rTMS is placed correctly to help treat their symptoms, and what changes in brain activity are happening during the rTMS treatment
Primary Outcome
A marker visible on MRI will be placed on the treatment location for the MRI scan after treatment completion. Functional MRI will be used to localize the dorsolateral prefrontal cortex (DLPFC), the brain region targeted by rTMS. The distance between these two points will be calculated for each participant.
Conditions Studied
Interventions
- DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Locations (2)
California
- VA Palo Alto Health Care System, Palo Alto, CA - Palo Alto
Rhode Island
- Providence VA Medical Center, Providence, RI - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2019-10-24 |
| Est. Completion | 2025-12-31 |
What the registry record for NCT04016402 still lists
NCT04016402 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 331-participant average among 47 other Depressive Disorder trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Depressive Disorder appearing as the primary indexed condition, and to 1 intervention - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.
NCT04016402 reports a single indexed study location in California, Rhode Island.
Frequently Asked Questions
What is clinical trial NCT04016402 about?
NCT04016402 is a clinical study titled "Imaging to Improve Brain Stimulation". This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS). People who receive rTMS will have pictures of their brains and brain activity taken by a magnetic resonance imaging (MRI) scanner before and after their tre...
What is the current status of trial NCT04016402?
This trial is currently active not recruiting. The enrollment target is 42 participants. The study started on 2019-10-24. Estimated completion is 2025-12-31.
What conditions does trial NCT04016402 study?
This clinical trial studies the following conditions: Depressive Disorder.
What interventions are being tested in trial NCT04016402?
The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).
Who is sponsoring clinical trial NCT04016402?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04016402 being conducted?
This trial has 2 study locations across California, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depressive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04016402's enrollment target sits among peer trials
42 37th of 47 higher than 11 of 47 other Depressive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depressive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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