VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 9 of 34

NOT YET RECRUITING NA

The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome

NCT06953778

NOT YET RECRUITING Phase 2

Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE)

NCT07649291

NOT YET RECRUITING NA

Maximizing Quality of Life After Cancer Through Rehabilitation

NCT07622407

NOT YET RECRUITING Early Phase 1

PTSD and Alcohol Couples Treatment for Veterans

NCT07388654

NOT YET RECRUITING NA

Peer Support for Whole Health for Veterans

NCT07387692

NOT YET RECRUITING NA

Exercise With and Without Cognitive Training

NCT07447115

NOT YET RECRUITING NA

Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0)

NCT07645274

NOT YET RECRUITING NA

VA Randomized Trial of Surveillance Intervals After Transurethral Resection of High Grade Bladder Tumors

NCT07408830

NOT YET RECRUITING Phase 2

Clinical and Neurocomputational Effects of Behavioral Activation in Veterans With Impaired Social Functioning

NCT07697001

NOT YET RECRUITING NA

De-implementing PreOp Urine Testing

NCT07411209

NOT YET RECRUITING NA

Improving Functioning Among Aging Women Veterans

NCT06580470

NOT YET RECRUITING Phase 3

Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine

NCT07361432

NOT YET RECRUITING NA

PNS to Improve Vascular Function and Limb Health in Veterans

NCT07696988

NOT YET RECRUITING NA

Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers

NCT07207473

NOT YET RECRUITING NA

An Intervention to Impact Cardiovascular Implantable Electronic Device Lead Models Implanted in Veterans

NCT05062434

NOT YET RECRUITING Phase 2

Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

NCT07528690

NOT YET RECRUITING

Development of a Socially Connected Exercise System for Wheelchair Users

NCT07189546

NOT YET RECRUITING NA

Recovery-oriented Group Therapy for Veteran Men With Military Sexual Trauma

NCT06741202

NOT YET RECRUITING NA

Targeting the Hip Abductors to Reduce Falls in Older Veterans Through A Virtual Multimodal Balance Intervention

NCT07109466

NOT YET RECRUITING NA

Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout

NCT06887452

NOT YET RECRUITING NA

Enhancing Mental and Physical Health of Women Veterans 3.0

NCT07356479

NOT YET RECRUITING Phase 4

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

NCT07210606

NOT YET RECRUITING

ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening

NCT06745258

NOT YET RECRUITING NA

Development of a Mobile Health Intervention to Support Functioning of Veterans With Substance Use Disorders

NCT07645131

NOT YET RECRUITING NA

Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation

NCT07648407

NOT YET RECRUITING NA

Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing

NCT07141394

NOT YET RECRUITING Early Phase 1

hCG Treatment for Rehabilitation From a TBI

NCT07557615

NOT YET RECRUITING Phase 2

LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial

NCT07645300

NOT YET RECRUITING NA

Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms

NCT07202325

NOT YET RECRUITING NA

Facilitation to Increase Tobacco Treatment

NCT07455526

NOT YET RECRUITING NA

Rapid Personalization of Safety Plans for Psychiatrically Hospitalized Veterans at High-Risk for Suicide

NCT07507786

NOT YET RECRUITING NA

EVOLV-Rx VA: Evaluating Opportunities to Decrease Low-Value Prescribing in Community Living Centers

NCT07166107

NOT YET RECRUITING NA

Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older Veterans

NCT06963970

NOT YET RECRUITING Phase 2

Allopregnanolone in Chronic Complex Traumatic Brain Injury

NCT04003285

NOT YET RECRUITING NA

Developing an Intervention to Optimize Virtual Care Adoption for COPD Management

NCT05986214

NOT YET RECRUITING NA

A Transdiagnostic Sleep Health Intervention for Veterans With PTSD

NCT06549049

NOT YET RECRUITING Phase 2

Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial

NCT05935761

NOT YET RECRUITING NA

Gamification and Physical Activity in PD

NCT07286994

NOT YET RECRUITING NA

User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems

NCT03494127

NOT YET RECRUITING NA

Veteran Peer Navigators to Promote Shared Decision Making for PSA Screening

NCT06549036

NOT YET RECRUITING NA

Improving Productive Community Integration in Homeless-experienced Veterans

NCT07388641

NOT YET RECRUITING NA

Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care

NCT07549178

NOT YET RECRUITING

Rehabilitating Vision Loss in Veterans With Age-Related Macular Degeneration

NCT05780931

NOT YET RECRUITING Phase 2

Focused Ultrasound for PTSD in Veterans

NCT06820138

NOT YET RECRUITING Phase 3

Basal Cell Carcinoma Chemoprevention Trial

NCT05212246

NOT YET RECRUITING NA

Facilitating Transition to Recommended PTSD Treatment

NCT05165940

NOT YET RECRUITING Phase 2

Vascular Effects of SGLT2i in Non-diabetic CKD

NCT07060417

NOT YET RECRUITING Phase 3

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

NCT07226232

NOT YET RECRUITING Phase 4

Varenicline for Smoking Reduction in Veterans Not Ready To Quit

NCT06966362

NOT YET RECRUITING NA

Algorithm-enabled Goals of Care Communication

NCT07690904

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.