VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 32 of 34

COMPLETED

Evidence Synthesis: Hypertension Medication Adherence & Intensification

NCT00682968

COMPLETED

Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury

NCT00676182

COMPLETED Phase 1

Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)

NCT00714571

COMPLETED NA

The Efficacy of Familiar Voice Stimulation During Coma Recovery

NCT00557076

COMPLETED

Understanding Different Parameters in Locomotor Training (a Type of Walking Training) for Person After a Stroke

NCT00712179

COMPLETED NA

Proteolytic Enzyme Induction Within the Human Myocardial Interstitium

NCT00744211

COMPLETED

Brain Injury Outcomes (BIO) Study

NCT00724607

COMPLETED NA

Pharmacist-led Group Medical Visits to Help With Diabetes Management

NCT00554671

COMPLETED NA

Exercise to Reduce Obesity in Spinal Cord Injury

NCT00270855

COMPLETED NA

Improving Medical Training for the Care of Chronic Conditions

NCT00676208

COMPLETED NA

Do Consumer Providers Enhance Recovery?

NCT00781079

TERMINATED Phase 4

PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation

NCT00645450

COMPLETED NA

Telehealth Outreach for Chronic Back Pain

NCT00608530

COMPLETED

The VA Diabetes Trial Follow-up Study (VADT-FS)

NCT00756613

COMPLETED NA

Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis

NCT00125658

COMPLETED NA

Illness Management and Recovery for Veterans With Severe Mental Illness

NCT00515671

COMPLETED Phase 2

Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms

NCT00475241

COMPLETED NA

Statin Therapy Versus Placebo Prior to Prostatectomy

NCT00572468

COMPLETED NA

Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)

NCT00386243

COMPLETED NA

An Intervention to Improve Function in Severe Cardiopulmonary Illness

NCT00467298

TERMINATED Phase 1

Can Simple and Inexpensive Techniques Enhance Patient Comfort

NCT00747084

TERMINATED Phase 2

Efficacy of Macrolide Immunomodulation in Severe Sepsis.

NCT00708799

COMPLETED

Awareness of Deficit After Combat-related Brain Injury

NCT00478400

COMPLETED NA

Depression and Congestive Heart Failure in Outpatients.

NCT00321269

COMPLETED Phase 4

Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)

NCT00385684

COMPLETED NA

Effects of Training on Central Auditory Function in Multiple Sclerosis

NCT01023074

COMPLETED NA

Central Auditory Processing Disorders Associated With Blast Exposure

NCT00554801

COMPLETED

Regional Anesthesia Military Battlefield Pain Outcomes Study

NCT00431847

TERMINATED NA

PDA+: A Personal Digital Assistant for Obesity Treatment

NCT00371462

COMPLETED

Senior Coordinated Referral Study

NCT00404118

COMPLETED NA

Improving Basic and Social Cognition in Veterans With Schizophrenia

NCT00470106

COMPLETED Phase 4

Methylphenidate for Apathy in Alzheimer's Dementia: A Controlled Study

NCT00495820

COMPLETED

MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care

NCT00400062

COMPLETED

A Biochip for Rapid Diagnosis of Complicated Urinary Tract Infection

NCT00591240

COMPLETED NA

Use of Telehealth In-home Messaging to Improve GI (Gastrointestinal) Endoscopy Completion Rates

NCT00310362

COMPLETED NA

Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)

NCT00137280

COMPLETED

Patient and Provider Attitudes in the Healthcare Context

NCT00404027

COMPLETED NA

The Effect of a Contingency Management Intervention on Substance Use

NCT00252512

TERMINATED NA

Mechanistically-based Optimization of UV Radiation Therapy in Psoriasis

NCT00470392

COMPLETED NA

Exercise and Inflammation in the Elderly

NCT00753363

COMPLETED NA

Use of Subtle Vibration to Improve Walking Ability by Lower Limb Amputees

NCT00985881

COMPLETED NA

Quality Improvement of Patient-Provider Communication For Colorectal Cancer Screening

NCT00324753

COMPLETED

Cardiovascular Disease Study

NCT00857194

COMPLETED NA

HIV Translating Initiatives for Depression Into Effective Solutions

NCT00304915

COMPLETED NA

Financial Incentives to Translate ALLHAT Into Practice: A Randomized Trial

NCT00302718

COMPLETED Phase 2

Development of NIC5-15 in the Treatment of Alzheimer's Disease

NCT00470418

COMPLETED NA

VISN Collaborative for Improving Hypertension Management With ATHENA-HTN

NCT00374452

COMPLETED Phase 2

5-Alpha Reductase and Anabolic Effects of Testosterone

NCT00475501

COMPLETED Phase 2

Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk

NCT00330733

COMPLETED NA

Effects of PPAR Ligands on Ectopic Fat Accumulation and Inflammation

NCT00470262

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.