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NCT00753363 · ClinicalTrials.gov registry record · NA
Exercise and Inflammation in the Elderly
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 119
- Enrollment target
NCT00753363: Completed NA study, sponsored by VA Office of Research and Development.
NCT00753363 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 119 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00753363, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 119 participants
- Enrollment target
Study Summary
Persistent low-grade inflammation and impaired fibrinolysis, are independent predictors of several chronic diseases highly prevalent in the older Veteran population including cardiovascular disease (CVD), stroke, and diabetes. Inflammation is likely to be a causative underlying mechanism of insulin resistance. Lifestyle changes such as weight loss and physical activity are advocated for the treatment of these chronic diseases and endpoints, and data are emerging which suggest that these treatments may be beneficial, in part, due to their anti-inflammatory effects. Identification of effective therapies that reduce chronic inflammation for Veterans is important given the widespread adverse health effects of a chronically elevated inflammatory state.
Primary Outcome
Insulin resistance is defined as a reduction in glucose utilization rate elicited by a given insulin concentration. Glucose utilization is measured during a three hour hyperinsulinemic-euglycemic clamp and is presented as a measure of insulin sensitivity. This is one of the most sophisticated methods to measure insulin sensitivity.
Interventions
- OTHER Aerobic Exercise Training
- OTHER Weight Loss
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2007-04-01 |
| Est. Completion | 2012-11-29 |
| Phase | NA |
What the finished NCT00753363 record still lists
NCT00753363 is an interventional study that assigns participants to a tested intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Aerobic Exercise Training is the first listed.
NCT00753363 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00753363 about?
NCT00753363 is a clinical study titled "Exercise and Inflammation in the Elderly". Persistent low-grade inflammation and impaired fibrinolysis, are independent predictors of several chronic diseases highly prevalent in the older Veteran population including cardiovascular disease (CVD), stroke, and diabetes. Inflammation is likely to be a causative underlying mechanism of insulin ...
What is the current status of trial NCT00753363?
This trial is currently completed. It is a NA study. The enrollment target is 119 participants. The study started on 2007-04-01. Estimated completion is 2012-11-29.
What interventions are being tested in trial NCT00753363?
The interventions under investigation include: Aerobic Exercise Training (OTHER), Weight Loss (OTHER).
Who is sponsoring clinical trial NCT00753363?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00753363's enrollment target sits among peer trials
119 803rd of 2000 higher than 1,198 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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