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NCT00321269 · ClinicalTrials.gov registry record · NA
Depression and Congestive Heart Failure in Outpatients.
A NA study of Depression and Heart Failure, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 134
- Enrollment target
- 2
- Study locations
NCT00321269: Completed NA study of Depression and Heart Failure, sponsored by VA Office of Research and Development.
NCT00321269 is a NA study of Depression and Heart Failure that has completed, run by VA Office of Research and Development. The registered enrollment target is 134 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (83% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00321269, a NA study of Depression and Heart Failure, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 134 participants
- Enrollment target
- 2
- Study locations
Study Summary
Patients with a diagnosis of CHF, NYHA class II, III or IV will be recruited for a study comparing a nursing intervention addressing CHF (SIM group) or CHF and depression (CIM group). Participants in the standard illness management program will receive an 8-week, 8-session intervention designed to help them improve daily weighing, salt-restriction, medication management, etc. This intervention will be conducted in a combination of home visits and phone visits. They will also receive interactive, telephone-based daily monitoring that assesses daily weight, dyspnea, fatigue and medication compliance. Patients in the comorbid illness management program will receive the same illness management program PLUS education and behavioral techniques designed to help them cope emotionally with the illness. The comorbid illness management home monitoring will include a twice-monthly screen for depression. Major Variables: The major outcomes will be depressive symptoms, health-related quality of life, functional status, heart failure symptom severity, and self-care behaviors in heart failure.
Primary Outcome
Depressive Symptoms measured on a Beck Depression Inventory Revised Possible Range 0 to 63. Higher scores indicate greater depression. Effectiveness of treatment indicated by a decline in the BDI-II score.
Conditions Studied
Interventions
- BEHAVIORAL Single Illness Management
- BEHAVIORAL Comorbid Illness Management
Study Locations (2)
Iowa
- Iowa City VA Medical Center - Iowa City
Missouri
- Harry S. Truman Memorial VA Medical Center - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2007-10 |
| Est. Completion | 2010-12 |
| Phase | NA |
What the finished NCT00321269 record still lists
NCT00321269 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Single Illness Management is the first listed.
NCT00321269 reports a single indexed study location in Iowa, Missouri.
Frequently Asked Questions
What is clinical trial NCT00321269 about?
NCT00321269 is a clinical study titled "Depression and Congestive Heart Failure in Outpatients.". Patients with a diagnosis of CHF, NYHA class II, III or IV will be recruited for a study comparing a nursing intervention addressing CHF (SIM group) or CHF and depression (CIM group). Participants in the standard illness management program will receive an 8-week, 8-session intervention designed to h...
What is the current status of trial NCT00321269?
This trial is currently completed. It is a NA study. The enrollment target is 134 participants. The study started on 2007-10. Estimated completion is 2010-12.
What conditions does trial NCT00321269 study?
This clinical trial studies the following conditions: Depression, Heart Failure.
What interventions are being tested in trial NCT00321269?
The interventions under investigation include: Single Illness Management (BEHAVIORAL), Comorbid Illness Management (BEHAVIORAL).
Who is sponsoring clinical trial NCT00321269?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00321269 being conducted?
This trial has 2 study locations across Iowa, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00321269's enrollment target sits among peer trials
134 278th of 679 higher than 400 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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